National Technical University of Athens

About: National Technical University of Athens is a education organization based out in Athens, Attiki, Greece. It is known for research contribution in the topics: Large Hadron Collider & Nonlinear system. The organization has 13445 authors who have published 31259 publications receiving 723504 citations. The organization is also known as: Athens Polytechnic & NTUA.

Mathematical modeling of infectious disease dynamics

Abstract: Over the last years, an intensive worldwide effort is speeding up the developments in the establishment of a global surveillance network for combating pandemics of emergent and re-emergent infectious diseases. Scientists from different fields extending from medicine and molecular biology to computer science and applied mathematics have teamed up for rapid assessment of potentially urgent situations. Toward this aim mathematical modeling plays an important role in efforts that focus on predicting, assessing, and controlling potential outbreaks. To better understand and model the contagious dynamics the impact of numerous variables ranging from the micro host–pathogen level to host-to-host interactions, as well as prevailing ecological, social, economic, and demographic factors across the globe have to be analyzed and thoroughly studied. Here, we present and discuss the main approaches that are used for the surveillance and modeling of infectious disease dynamics. We present the basic concepts underpinning ...

A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy.

Abstract: Purpose To propose a new index (COIN) that can be easily understood and computed to assess high dose rate (HDR) brachytherapy interstitial implant quality and dose specification and is an improvement on existing indexes. Methods and materials The COIN index is based on an extension of dose-volume histograms and employs an analogous concept to that of cost-benefit analysis, which has already been applied to quality-of-life assessments for two alternative treatment protocols. The COIN index calculation methodology is shown for two cases: with and without critical structures. An analysis is given of dose distributions for two planning treatment volumes (PTV) of simple geometrical shape, applying both the rules of the Paris system and that of the "Offenbach" system. 40 patients who have received interstitial implants form the clinical material. With current HDR brachytherapy technology both for dose delivery, using remote afterloaders, and for three-dimensional (3D) treatment planning, it is now possible to relatively easily plan conformal brachytherapy treatments that would have been impossible with manual afterloading techniques and two-dimensional (2D) treatment planning. Results Examples of the use of the COIN index are presented for experimental and clinical data. Conclusions The results show that COIN is a useful and practical index to improve the quality of treatment of interstitial brachytherapy implants. Further work will be undertaken with a larger population of implanted cancer patients and a subdivision of the results by treatment site.

Performance of pile-up mitigation techniques for jets in pp collisions at √s = 8 TeV using the ATLAS detector

Abstract: The large rate of multiple simultaneous protonproton interactions, or pile-up, generated by the Large Hadron Collider in Run 1 required the development of many new techniques to mitigate the advers ...

Dijet cross sections and parton densities in diffractive DIS at HERA

Abstract: Differential dijet cross sections in diffractive deep-inelastic scattering are measured with the H1 detector at HERA using an integrated luminosity of 51.5 pb−1. The selected events are of the type ep → eXY , where the system X contains at least two jets and is well separated in rapidity from the low mass proton dissociation system Y . The dijet data are compared with QCD predictions at next-to-leading order based on diffractive parton distribution functions previously extracted from measurements of inclusive diffractive deepinelastic scattering. The prediction describes the dijet data well at low and intermediate zIP (the fraction of the momentum of the diffractive exchange carried by the parton entering the hard interaction) where the gluon density is well determined from the inclusive diffractive data, supporting QCD factorisation. A new set of diffractive parton distribution functions is obtained through a simultaneous fit to the diffractive inclusive and dijet cross sections. This allows for a precise determination of both the diffractive quark and gluon distributions in the range 0.05 < zIP < 0.9. In particular, the precision on the gluon density at high momentum fractions is improved compared to previous extractions.