Primary Children's Hospital

About: Primary Children's Hospital is a healthcare organization based out in Salt Lake City, Utah, United States. It is known for research contribution in the topics: Population & Health care. The organization has 1770 authors who have published 2594 publications receiving 107857 citations. The organization is also known as: Intermountain Primary Children's Medical Center & Intermountain Primary Children's Hospital.

Parents' perceptions of a pediatric palliative program.

Abstract: Reports of family satisfaction with pediatric palliative care have been limited. This knowledge is critical for both program development and furthering understanding of needs. The purpose of this study was to assess parents' perceptions about whether a pediatric palliative care program was providing key elements of pediatric palliative care as described in the literature and to assess parental satisfaction with services. Data were collected from 65 parents, using a tool developed for the project, whose children died while receiving services from Rainbow Kids Palliative Care, a program of Primary Children's Medical Center, and the Department of Pediatrics, University of Utah, Salt Lake City, Utah. Respondents reported that the Rainbow Kids team had provided emotional support, helped with decision making and communication, and that their children's symptoms were managed. Furthermore, parent respondents expressed high levels of satisfaction with services from the Rainbow Kids team.

Pediatric Laboratory MedicineCurrent Challenges and Future Opportunities

Abstract: The practice of pediatric laboratory medicine involves unique challenges related to development, nutrition, growth, and diseases during different periods of infancy, childhood, and adolescence. This article discusses key aspects of pediatric laboratory medicine faced by clinical pathologists, clinical laboratory scientists, and clinicians, including point-of-care testing, preanalytic variables, analytic factors, age-specific reference intervals, esoteric laboratory tests, clinical impact, and future opportunities. Although challenging, pediatric laboratory testing offers many opportunities for improved patient care, clinical- and laboratory-based research, and education.

Granulocyte transfusion in septic canine neonates.

Abstract: Summary: Newborn dogs were inoculated intratracheally with 0.5–1.0 x 108 Staphylococcus aureus/g body weight. Neutropenia (490 ± 280 neutrophils/mm3 versus 8,390 ± 490 control, ± S.E., P< 0.001), and depletion of the marrow neutrophil storage pool (3 ± 1% versus 27 ± 2% storage neutrophils P < 0.001) occurred 5–6 h following the inoculation. All animals died at 6–10 h. Additional inoculated pups were selected at random to receive transfusions of either granulocytes, plasma or red blood cells. Granulocyte transfusions (3x109 neutrophils/kg) improved survival (P < 0.005), but plasma and red blood cells did not. Speculation: Previous reports have shown that certain neonates with bacterial sepsis utilize neutrophils more rapidly than they are replaced by the marrow mitotic neutrophil pool. The quantitative neutrophil deficiency thus produced, results in blood neutropenia, reduced neutrophil availability to affected tissues and high mortality. In this study, neonatal dogs were infected experimentally and found to develop neutropenia, depletion of neutrophil reserves, and death. Granulocyte transfusions improved the survival of these animals while plasma or packed red blood cell transfusions did not. Thus, granulocyte transfusion may present a useful therapeutic modality in those septic neonates who are found to have neutropenia and a depleted neutrophil supply.