Institution
Primary Children's Hospital
Healthcare•Salt Lake City, Utah, United States•
About: Primary Children's Hospital is a healthcare organization based out in Salt Lake City, Utah, United States. It is known for research contribution in the topics: Population & Health care. The organization has 1770 authors who have published 2594 publications receiving 107857 citations. The organization is also known as: Intermountain Primary Children's Medical Center & Intermountain Primary Children's Hospital.
Topics: Population, Health care, Transplantation, Poison control, Medicine
Papers published on a yearly basis
Papers
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TL;DR: An investigation on the immune systems of patients with autism has revealed several immune-system abnormalities, including reduced responsiveness in the lymphocyte blastogenesis assay to phytohemagglutinin, concanavalin A, and pokeweed mitogen; decreased numbers of T lymphocytes; and an altered ratio of helper to suppressor T cells.
Abstract: We have begun an investigation on the immune systems of patients with autism in attempt to determine if immune mechanisms are involved in the development of this severe developmental disorder. A study of 31 autistic patients has revealed several immune-system abnormalities, including reduced responsiveness in the lymphocyte blastogenesis assay to phytohemagglutinin, concanavalin A, and pokeweed mitogen; decreased numbers of T lymphocytes; and an altered ratio of helper to suppressor T cells. Immune-system abnormalities may be directly related to underlying biologic processes of autism, or these changes may be an indirect reflection of the actual pathologic mechanism.
203 citations
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TL;DR: Technical variant techniques expand the pediatric donor pool and reduce time from listing to transplant, but they are associated with increased morbidity and mortality.
Abstract: Objective:To examine the outcome of technical variant liver transplant techniques relative to whole organ liver transplantation in pediatric liver transplant recipients.Background:Technical variant liver transplant techniques comprising split, reduced, and live-donor liver transplantation evolved to
202 citations
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TL;DR: In an effort to reduce the ventriculoperitoneal shunt infection rate, a standardized protocol was developed and implemented at 4 centers of the Hydrocephalus Clinical Research Network (HCRN) as mentioned in this paper.
Abstract: Object Quality improvement techniques are being implemented in many areas of medicine. In an effort to reduce the ventriculoperitoneal shunt infection rate, a standardized protocol was developed and implemented at 4 centers of the Hydrocephalus Clinical Research Network (HCRN). Methods The protocol was developed sequentially by HCRN members using the current literature and prior institutional experience until consensus was obtained. The protocol was prospectively applied at each HCRN center to all children undergoing a shunt insertion or revision procedure. Infections were defined on the basis of CSF, wound, or pseudocyst cultures; wound breakdown; abdominal pseudocyst; or positive blood cultures in the presence of a ventriculoatrial shunt. Procedures and infections were measured before and after protocol implementation. Results Twenty-one surgeons at 4 centers performed 1571 procedures between June 1, 2007, and February 28, 2009. The minimum follow-up was 6 months. The Network infection rate decreased fr...
199 citations
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TL;DR: Haplotype analyses indicate that a gene causing DCM associated with rhythm and conduction abnormalities is located on chromosome 3p, and represent the first step toward disease gene identification.
Abstract: Dilated cardiomyopathy (DCM) is a common disorder characterized by cardiac dilation and reduced systolic function. To identify a cardiomyopathy gene, we studied a family with DCM associated with sinus node dysfunction, supraventricular tachyarrhythmias, conduction delay, and stroke. A general linkage approach was used to localize the disease gene in this family. Linkage to D3S2303 was identified with a two-point lod score of 6.09 at a recombination fraction of 0.00. Haplotype analyses mapped this locus to a 30 cM region of chromosome 3p22-p25, excluding candidate genes encoding a G-protein (GNAI2), calcium channel (CACNL1A2), sodium channel (SCN5A), and inositol triphosphate receptor (ITPR1). These data indicate that a gene causing DCM associated with rhythm and conduction abnormalities is located on chromosome 3p, and represent the first step toward disease gene identification.
198 citations
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Freeman Hospital1, University of Toronto2, Stanford University3, Columbia University Medical Center4, Great Ormond Street Hospital5, Boston Children's Hospital6, Primary Children's Hospital7, Cincinnati Children's Hospital Medical Center8, Children's Memorial Hospital9, Children's Hospital of Philadelphia10
TL;DR: From the Freeman Hospital, Newcastle upon Tyne, United Kingdom, the Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada, Stanford University, Stanford, California, and the Royal Melbourne Children’s Hospital, Melbourne, Victoria, Australia.
Abstract: From the Freeman Hospital, Newcastle upon Tyne, United Kingdom; Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; Stanford University, Stanford, California; Columbia University Medical Center, New York, New York; Great Ormond Street Hospital, London, United Kingdom; Joe DiMaggio Children’s Hospital, Hollywood, Florida; Primary Children’s Medical Center, Salt Lake City, Utah; C.S. Mott Children’s Hospital, Ann Arbor, Michigan; Children’s Hospital, Denver, Colorado; Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; Ann & Robert H Lurie Children’s Hospital, Chicago, Illinois; Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania; and the Royal Melbourne Children’s Hospital, Melbourne, Victoria, Australia.
196 citations
Authors
Showing all 1777 results
Name | H-index | Papers | Citations |
---|---|---|---|
Scott Thomas | 131 | 1219 | 85507 |
Michael R. Bristow | 113 | 508 | 60747 |
Ikuo Ueda | 106 | 1053 | 48642 |
David Robinson | 101 | 757 | 38372 |
Pedram Argani | 97 | 372 | 35607 |
Glenn D. Prestwich | 88 | 690 | 42758 |
Melvin M. Scheinman | 86 | 531 | 25883 |
John M. Opitz | 85 | 1193 | 40257 |
George R. Saade | 82 | 872 | 30325 |
James Neil Weinstein | 81 | 325 | 24918 |
Michael Charlton | 79 | 333 | 28494 |
James M. Ford | 79 | 314 | 20750 |
Michael W. Varner | 74 | 405 | 19346 |
Murray D. Mitchell | 74 | 540 | 20408 |
Jeffrey L. Anderson | 73 | 300 | 25916 |