Institution
Primary Children's Hospital
Healthcare•Salt Lake City, Utah, United States•
About: Primary Children's Hospital is a healthcare organization based out in Salt Lake City, Utah, United States. It is known for research contribution in the topics: Population & Health care. The organization has 1770 authors who have published 2594 publications receiving 107857 citations. The organization is also known as: Intermountain Primary Children's Medical Center & Intermountain Primary Children's Hospital.
Topics: Population, Health care, Transplantation, Poison control, Medicine
Papers published on a yearly basis
Papers
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TL;DR: The case of a 12-year-old boy who had severe Crohn's disease and a nasal septal perforation is reported and this complication is discussed in the context of its otolaryngologic manifestations.
Abstract: Nasal manifestations of Crohn's disease are quite rare. They are typified by chronic mucosal inflammation, obstruction, bleeding, and occasionally septal perforation--signs and symptoms that are common to many disease states of the nose. Nasal findings, much like oral lesions, can precede the more typical gastroenterologic manifestations of Crohn's disease. Otolaryngologists should be aware of such an association and consider the diagnosis of Crohn's disease in atypical cases of nasal disease. We report the case of a 12-year-old boy who had severe Crohn's disease and a nasal septal perforation, and we discuss this complication in the context of its otolaryngologic manifestations.
38 citations
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Cincinnati Children's Hospital Medical Center1, University of Southern California2, Children's Hospital of Philadelphia3, Baylor College of Medicine4, Primary Children's Hospital5, Johns Hopkins University6, Children's Oncology Group7, St. Jude Children's Research Hospital8, New York University9, University of Colorado Boulder10, University of California, San Francisco11
TL;DR: This single arm phase 2 trial enrolled pts age 1-21 years with CD22-positive B-ALL in >2nd relapse, refractory to 2 prior induction regimens, any relapse after HSCT, or 1st relapse with Down syndrome, and evaluated InO for response/toxicity.
38 citations
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TL;DR: In four children with communicating Hydrocephalus the development of the hydrocephalus appears to be related to the use of bilateral jugular catheters inserted for total parenteral nutrition.
38 citations
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University of Toronto1, University of Michigan2, Duke University3, Medical University of South Carolina4, Children's Hospital of Philadelphia5, Columbia University6, Children's Hospital Los Angeles7, Boston Children's Hospital8, Cincinnati Children's Hospital Medical Center9, Alfred I. duPont Hospital for Children10, All Children's Hospital11, Primary Children's Hospital12, Emory University13, Children's Hospital of Wisconsin14
TL;DR: Nonelective stage 2 procedure, moderate or greater AVV regurgitation, and need for AVV repair are among the risk factors for death in Norwood LOS, but not shunt type, is independently associated with longer LOS.
38 citations
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University of Pennsylvania1, University of Michigan2, University of Utah3, Boston Children's Hospital4, University of Toronto5, University of Southern California6, Primary Children's Hospital7, Children's National Medical Center8, Washington University in St. Louis9, University of Texas Southwestern Medical Center10, Columbia University11, Duke University12, Children's Memorial Hospital13, University of Pittsburgh14, Children's Hospital Oakland Research Institute15, University of Rochester16, University of Louisville17, Medical College of Wisconsin18, University of California, Los Angeles19, University of California, Irvine20, University of Minnesota21, Cincinnati Children's Hospital Medical Center22, Johns Hopkins University23, Nationwide Children's Hospital24, Loma Linda University25, University of Tennessee Health Science Center26, University of Texas Health Science Center at San Antonio27, University of Arkansas for Medical Sciences28, National Institutes of Health29
TL;DR: Early post–cardiac arrest hypotension was associated with lower odds of discharge survival, even after adjusting for covariates of interest, in the THAPCA trial.
Abstract: Importance Out-of-hospital cardiac arrest (OHCA) occurs in more than 6000 children each year in the United States, with survival rates of less than 10% and severe neurologic morbidity in many survivors. Post-cardiac arrest hypotension can occur, but its frequency and association with survival have not been well described during targeted temperature management. Objective To determine whether hypotension is associated with survival to discharge in children and adolescents after resuscitation from OHCA. Design, setting, and participants This post hoc secondary analysis of the Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) trial included 292 pediatric patients older than 48 hours and younger than 18 years treated in 36 pediatric intensive care units from September 1, 2009, through December 31, 2012. Participants underwent therapeutic hypothermia (33.0°C) vs therapeutic normothermia (36.8°C) for 48 hours. All participants had hourly systolic blood pressure measurements documented during the initial 6 hours of temperature intervention. Hourly blood pressures beginning at the time of temperature intervention (time 0) were normalized for age, sex, and height. Early hypotension was defined as a systolic blood pressure less than the fifth percentile during the first 6 hours after temperature intervention. With use of forward stepwise logistic regression, covariates of interest (age, sex, initial cardiac rhythm, any preexisting condition, estimated duration of cardiopulmonary resuscitation [CPR], primary cause of cardiac arrest, temperature intervention group, night or weekend cardiac arrest, witnessed status, and bystander CPR) were evaluated in the final model. Data were analyzed from February 5, 2016, through June 13, 2017. Exposures Hypotension. Main outcomes and measure Survival to hospital discharge. Results Of 292 children (194 boys [66.4%] and 98 girls [33.6%]; median age, 23.0 months [interquartile range, 5.0-105.0 months]), 78 (26.7%) had at least 1 episode of early hypotension. No difference was observed between the therapeutic hypothermia and therapeutic normothermia groups in the prevalence of hypotension during induction and maintenance (73 of 153 [47.7%] vs 72 of 139 [51.8%]; P = .50) or rewarming (35 of 118 [29.7%] vs 19 of 95 [20.0%]; P = .10) during the first 72 hours. Participants who had early hypotension were less likely to survive to hospital discharge (20 of 78 [25.6%] vs 93 of 214 [43.5%]; adjusted odds ratio, 0.39; 95% CI, 0.20-0.74). Conclusions and relevance In this post hoc secondary analysis of the THAPCA trial, 26.7% of participants had hypotension within 6 hours after temperature intervention. Early post-cardiac arrest hypotension was associated with lower odds of discharge survival, even after adjusting for covariates of interest.
38 citations
Authors
Showing all 1777 results
Name | H-index | Papers | Citations |
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Scott Thomas | 131 | 1219 | 85507 |
Michael R. Bristow | 113 | 508 | 60747 |
Ikuo Ueda | 106 | 1053 | 48642 |
David Robinson | 101 | 757 | 38372 |
Pedram Argani | 97 | 372 | 35607 |
Glenn D. Prestwich | 88 | 690 | 42758 |
Melvin M. Scheinman | 86 | 531 | 25883 |
John M. Opitz | 85 | 1193 | 40257 |
George R. Saade | 82 | 872 | 30325 |
James Neil Weinstein | 81 | 325 | 24918 |
Michael Charlton | 79 | 333 | 28494 |
James M. Ford | 79 | 314 | 20750 |
Michael W. Varner | 74 | 405 | 19346 |
Murray D. Mitchell | 74 | 540 | 20408 |
Jeffrey L. Anderson | 73 | 300 | 25916 |