Institution
Rovira i Virgili University
Education•Tarragona, Spain•
About: Rovira i Virgili University is a education organization based out in Tarragona, Spain. It is known for research contribution in the topics: Population & Catalysis. The organization has 4247 authors who have published 9141 publications receiving 236256 citations.
Topics: Population, Catalysis, Laser, Context (language use), Slope efficiency
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Procyanidins have insulin-like effects in insulin-sensitive cells that could help to explain their antihyperglycemic effect in vivo, which was significantly increased if PE administration was accompanied by a low insulin dose.
Abstract: Flavonoids are functional constituents of many fruits and vegetables. Some flavonoids have antidiabetic properties because they improve altered glucose and oxidative metabolisms of diabetic states. Procyanidins are flavonoids with an oligomeric structure, and it has been shown that they can improve the pathological oxidative state of a diabetic situation. To evaluate their effects on glucose metabolism, we administered an extract of grape seed procyanidins (PE) orally to streptozotocin-induced diabetic rats. This had an antihyperglycemic effect, which was significantly increased if PE administration was accompanied by a low insulin dose. The antihyperglycemic effect of PE may be partially due to the insulinomimetic activity of procyanidins on insulin-sensitive cell lines. PE stimulated glucose uptake in L6E9 myotubes and 3T3-L1 adipocytes in a dose-dependent manner. Like insulin action, the effect of PE on glucose uptake was sensitive to wortmannin, an inhibitor of phosphoinositol 3-kinase and to SB203580, an inhibitor of p38 MAPK. PE action also stimulated glucose transporter-4 translocation to the plasma membrane. In summary, procyanidins have insulin-like effects in insulin-sensitive cells that could help to explain their antihyperglycemic effect in vivo. These effects must be added to their antioxidant activity to explain why they can improve diabetic situations.
365 citations
••
TL;DR: In this article, the authors analyzed 14 marine species for the concentrations of omega-3 fatty acids, as well as a number of metals and organic pollutants, and calculated the monthly fish consumption limits for human health endpoints based on the intake of these chemical contaminants.
362 citations
••
TL;DR: This paper survey and classify most of the ontology-based approaches developed in order to evaluate their advantages and limitations and compare their expected performance both from theoretical and practical points of view, and presents a new ontological-based measure relying on the exploitation of taxonomical features.
Abstract: Estimation of the semantic likeness between words is of great importance in many applications dealing with textual data such as natural language processing, knowledge acquisition and information retrieval. Semantic similarity measures exploit knowledge sources as the base to perform the estimations. In recent years, ontologies have grown in interest thanks to global initiatives such as the Semantic Web, offering an structured knowledge representation. Thanks to the possibilities that ontologies enable regarding semantic interpretation of terms many ontology-based similarity measures have been developed. According to the principle in which those measures base the similarity assessment and the way in which ontologies are exploited or complemented with other sources several families of measures can be identified. In this paper, we survey and classify most of the ontology-based approaches developed in order to evaluate their advantages and limitations and compare their expected performance both from theoretical and practical points of view. We also present a new ontology-based measure relying on the exploitation of taxonomical features. The evaluation and comparison of our approach's results against those reported by related works under a common framework suggest that our measure provides a high accuracy without some of the limitations observed in other works.
361 citations
••
TL;DR: This paper has reviewed the main research studies that have been made of gas sensors that use nanomaterials and made a critical review of the possible advantages and drawbacks of these nanostructured material-based sensors.
Abstract: Gas detection is important for controlling industrial and vehicle emissions, household security and environmental monitoring. In recent decades many devices have been developed for detecting CO2, CO, SO2, O2, O3, H2, Ar, N2, NH3, H2O and several organic vapours. However, the low selectivity or the high operation temperatures required when most gas sensors are used have prompted the study of new materials and the new properties that come about from using traditional materials in a nanostructured mode. In this paper, we have reviewed the main research studies that have been made of gas sensors that use nanomaterials. The main quality characteristics of these new sensing devices have enabled us to make a critical review of the possible advantages and drawbacks of these nanostructured material-based sensors.
360 citations
••
TL;DR: The accumulation of different PFASs in samples of various human tissues from the same subjects is reported for the very first time and may be of high importance for the validation of physiologically based pharmacokinetic models, which are being developed for humans.
360 citations
Authors
Showing all 4370 results
Name | H-index | Papers | Citations |
---|---|---|---|
Steven P. Nolan | 110 | 744 | 47671 |
Jordi Rello | 103 | 694 | 35994 |
Jordi Salas-Salvadó | 90 | 624 | 33980 |
Vikas Kumar | 89 | 859 | 39185 |
José L. Domingo | 83 | 715 | 27914 |
Josep Guarro | 78 | 687 | 24875 |
Lei Zhang | 78 | 1485 | 30058 |
Josep Font | 78 | 355 | 24356 |
Richard G. Wunderink | 72 | 368 | 26892 |
Andrés Rodríguez-Pose | 68 | 296 | 16331 |
Alex Arenas | 67 | 325 | 28262 |
Rosa Maria Marcé | 66 | 250 | 12665 |
Antonio M. Echavarren | 65 | 370 | 20141 |
Gheorghe Paun | 65 | 399 | 18513 |
Ramon A. Alvarez-Puebla | 63 | 199 | 13457 |