Sharda University

About: Sharda University is a education organization based out in Greater Noida, Uttar Pradesh, India. It is known for research contribution in the topics: Computer science & Medicine. The organization has 1276 authors who have published 2012 publications receiving 16188 citations.

Waste plastics derived graphene nanosheets for supercapacitor application

Abstract: Given the non-biodegradable nature of plastic, its recycling and upcycling are critical to ensure effective waste management and resource conservation, with a cradle-to-cradle approach. Herewith, w...

Scavenging Properties of Plant-Derived Natural Biomolecule Para-Coumaric Acid in the Prevention of Oxidative Stress-Induced Diseases

Abstract: Para-coumaric acid (p-CA) is a plant derived secondary metabolite belonging to the phenolic compounds. It is widely distributed in the plant kingdom and found mainly in fruits, vegetables, and cereals. Various in vivo and in vitro studies have revealed its scavenging and antioxidative properties in the reduction of oxidative stress and inflammatory reactions. This evidence-based review focuses on the protective role of p-CA including its therapeutic potential. p-CA and its conjugates possesses various bioactivities such as antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, and anti-melanogenic properties. Due to its potent free radical scavenging activity, it can mitigate the ill effects of various diseases including arthritis, neurological disorders, and cardio-vascular diseases. Recent studies have revealed that p-CA can ameliorate the harmful effects associated with oxidative stress in the reproductive system, also by inhibiting enzymes linked with erectile function.

Road accident prediction and model interpretation using a hybrid K-means and random forest algorithm approach

Abstract: Road accident severity is a major concern of the world, particularly in underdeveloped countries. Understanding the primary and contributing factors may combat road traffic accident severity. This study identified insights and the most significant target specific contributing factors for road accident severity. To get the most determinant road accident variables, a hybrid K-means and random forest (RF) approaches developed. K-means extract hidden information from road accident data and creates a new feature in the training set. The distance between each cluster and the joining line of k1 and k9 calculated and selected maximum value as k. k is an optimal value for the partition of the training set. RF employed to classify severity prediction. After comparing with other classification techniques, the result revealed that among classification techniques, the proposed approach disclosed an accuracy of 99.86%. The target-specific model interpretation result showed that driver experience and day, light condition, driver age, and service year of the vehicle were the strong contributing factors for serious injury, light injury, and fatal severity, respectively. The outcome demonstrates the predictive supremacy of the approach in road accident prediction. Road transport and insurance agencies will be benefited from the study to develop road safety strategies.

Hairy Root Culture an Alternative for Bioactive Compound Production from Medicinal Plants.

Abstract: Medicinal plants produce a diverse group of phytocompounds like anthraquinones, alkaloids, anthocyanins, flavonoids, saponins, and terpenes which are used in pharmaceutical, perfume, cosmetics, dye and flavor industries. Commercial source of these metabolites is field-grown plants, which are generally influenced by seasonal changes. Biotechnology possesses a significant role in production of high-value secondary metabolites. By incorporating biotechnological methods, it is feasible to manage biosynthetic pathways of the plant to enhance phytocompound production that is of pharmaceutical interest. Plant cell suspension, shoot, adventitious root and hairy root culture are considered as alternative methods for important bioactive compound production. These methods are controllable, sustainable and overcome several inconveniences for large scale secondary metabolites production. At present research on hairy root culture for valuable bioactive compound production has gained a lot of attention. Agrobacterium rhizogenes is an agent which causes hairy root disease in a plant and this leads to the neoplastic growth of root which is characterized by higher growth rate and genetic stability. Various studies explore the hairy root culture for production of a wide range of bioactive compounds. Scale-up of hairy root culture using bioreactors has provided an opportunity to enhance bioactive compound production at the commercial level. The present review discusses the role of hairy root culture in the production of valuable bioactive compounds, the effect of culture parameters on bioactive compound production and bioreactor applications.

Effect of variation of average pore size and specific surface area of ZnO electrode (WE) on efficiency of dye-sensitized solar cells

Abstract: Mesoporous ZnO nanoparticles have been synthesized with tremendous increase in specific surface area of up to 578 m2/g which was 5.54 m2/g in previous reports (J. Phys. Chem. C 113:14676-14680, 2009). Different mesoporous ZnO nanoparticles with average pore sizes ranging from 7.22 to 13.43 nm and specific surface area ranging from 50.41 to 578 m2/g were prepared through the sol-gel method via a simple evaporation-induced self-assembly process. The hydrolysis rate of zinc acetate was varied using different concentrations of sodium hydroxide. Morphology, crystallinity, porosity, and J-V characteristics of the materials have been studied using transmission electron microscopy (TEM), X-ray diffraction (XRD), BET nitrogen adsorption/desorption, and Keithley instruments.