Sharda University

About: Sharda University is a education organization based out in Greater Noida, Uttar Pradesh, India. It is known for research contribution in the topics: Computer science & Medicine. The organization has 1276 authors who have published 2012 publications receiving 16188 citations.

Characterization of Fe3+-doped silver phosphate glasses

Abstract: The relationship among the composition, structure and selected properties for five series of silver phosphate glasses containing 0, 5, 10, 15 and 20 wt% Fe2O3 has been investigated. The synthesized glasses have been characterized using different experimental techniques. X-ray diffraction studies revealed that the glasses are amorphous in nature. IR spectral studies have shown the presence of characteristic P–O–P linkages of linear phosphate chains, presence of O–P–O units in the phosphate tetrahedral and the formation of P–O–Fe bonds in the doped glass. It is also confirmed that due to doping of Fe2O3, loosening of glassy structure occurred and the glass became more disordered. Differential scanning calorimetric (DSC) studies revealed that glass transition temperature increased with Fe2O3 concentration. Scanning electron microscopic studies have shown that Fe2O3 doping modifies the microstructures of the glass and at lower concentration of dopant, a nanostructure is obtained. Electrical conductivity measurements from 303 to 373 K in a frequency range from 100 Hz to 5 MHz have indicated that all glasses are ionic conductors with Ag+ ions as the charge carrier. Fe2O3 doping in silver phosphate glass increased the electrical conductivities. Results have shown that dielectric constants increased with the increase of temperature at all the frequencies; a.c. and d.c. conductivities have been separated and a Cole–Cole plot is also drawn. Dielectric losses in all the glasses decreased with frequency at a particular temperature. It is found that Ag2O–P2O5 glass doped with 5 wt% Fe2O3 gives high OCV value and the doped glass can be used as an electrolyte for solid-state batteries.

Environmental factors-induced oxidative stress: Hormonal and molecular pathway disruptions in hypogonadism and erectile dysfunction

Abstract: Hypogonadism is an endocrine disorder characterized by inadequate serum testosterone production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic-pituitary-gonadal axis. Erectile dysfunction (ED) is another common disorder in men that involves an alteration in erectile response-organic, relational, or psychological. The incidence of hypogonadism and ED is common in men aged over 40 years. Hypogonadism (including late-onset hypogonadism) and ED may be linked to several environmental factors-induced oxidative stresses. The factors mainly include exposure to pesticides, radiation, air pollution, heavy metals and other endocrine-disrupting chemicals. These environmental risk factors may induce oxidative stress and lead to hormonal dysfunctions. To better understand the subject, the study used many keywords, including "hypogonadism", "late-onset hypogonadism", "testosterone", "erectile dysfunction", "reactive oxygen species", "oxidative stress", and "environmental pollution" in major online databases, such as SCOPUS and PUBMED to extract relevant scientific information. Based on these parameters, this review summarizes a comprehensive insight into the important environmental issues that may have a direct or indirect association with hypogonadism and ED in men. The study concludes that environmental factors-induced oxidative stress may cause infertility in men. The hypothesis and outcomes were reviewed critically, and the mechanistic approaches are applied through oxidant-sensitive pathways. This study also provides reccomendations on future therapeutic interventions and protective measures against such adverse environmental factors-induced hypogonadism and ED.

A sustainable process for adsorptive removal of methylene blue onto a food grade mucilage: kinetics, thermodynamics, and equilibrium evaluation

Abstract: Adsorption of dyes onto natural materials like polysaccharides is considered a green chemistry approach for remediation of wastewater. In this work, the polysaccharide isolated from the cor...

Synthesis, Characterization, and Detailed Studies on Plasticized Poly(ethyl methacrylate): NH4I Polymer Electrolyte

Abstract: Polymer electrolyte films of poly(ethyl methacrylate) (PEMA) with ethylene carbonate (EC) as a plasticizer and ammonium iodide (NH4I) as an ion-donating salt have been prepared using the solution-cast technique. The electrical characterization of the films was performed by impedance spectroscopy. The highest obtained ionic conductivity at room temperature was 1.16 × 10−5 S/cm with the composition of PEMA: NH4I (60:40) + 10% EC. The ionic transference number of the mobile ions estimated by the dc polarization method, and the H+ ionic transference number was found to be ∼0.85, which revealed that the conductivity species are predominantly ions. Likewise, the micrographs of the films were analyzed under an optical microscope. In addition, the charge carrier density (n) of the individual films was calculated on the basis of the dielectric constant study.

Structure, function and role of CD44 in neoplasia.

Abstract: CD44 is a group of protein molecules which perform a variety of functions. Their wide range of functions are mainly based on their multiple variations in their molecular structure. Furthermore, they are distributed in various tissues of the human body. They have a unique property of cell adhesion, which can lead to interaction between two different cells or a cell and its pericellular matrix. CD44 as a cell surface adhesive molecule helps in aggregation and migration of tumor cells. CD44 plays an important role in cancer of bladder, liver, lungs, pancreas, etc. Expression profile of CD44 has been seen in the epithelia of the lip, tongue, gingiva, hard palate, floor of the mouth, buccal mucosa and pharynx. The relationship between the expression of CD44 v6 and regional lymph node metastasis has been studied immunohistochemically. The expression of CD44 v6 was apparently downregulated in oral squamous cell carcinoma, but not in normal oral mucosa. Carcinomas expressing lower levels of CD44 v6 exhibited more frequent regional lymph node metastasis. No significant relation was found between the expression of CD44 v6 in primary and metastatic lesions. Still, the precise function of CD44 in the metastatic process and the degree of involvement in human malignancies is yet to be established.