Institution
Tabriz University of Medical Sciences
Education•Tabriz, Iran•
About: Tabriz University of Medical Sciences is a education organization based out in Tabriz, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 11499 authors who have published 17525 publications receiving 241099 citations.
Topics: Population, Cancer, Medicine, Solubility, Randomized controlled trial
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the effects of hypoxia on tumor biology and the possible strategiesto manage the hypoxic tumor microenvironment (TME), highlighting the potential use of cancer stem cells in tumor treatment.
Abstract: Hypoxia is a common feature of solid tumors, and develops because of the rapid growth of the tumor that outstrips the oxygen supply, and impaired blood flow due to the formation of abnormal blood vessels supplying the tumor. It has been reported that tumor hypoxia can: activate angiogenesis, thereby enhancing invasiveness and risk of metastasis; increase survival of tumor, as well as suppress anti-tumor immunity and hamper the therapeutic response. Hypoxia mediates these effects by several potential mechanisms: altering gene expression, the activation of oncogenes, inactivation of suppressor genes, reducing genomic stability and clonal selection. We have reviewed the effects of hypoxia on tumor biology and the possible strategiesto manage the hypoxic tumor microenvironment (TME), highlighting the potential use of cancer stem cells in tumor treatment.
192 citations
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TL;DR: The role of NPs in treating cancer among different drug delivery methods for cancer therapy is discussed and a wide range of nanomaterials based on organic, inorganic, lipid, or glycan compounds, as well as on synthetic polymers has been utilized for the development of new cancer therapeutics.
Abstract: Rapid growth in nanotechnology toward the development of nanomedicine agents holds massive promise to improve therapeutic approaches against cancer. Nanomedicine products represent an opportunity to achieve sophisticated targeting strategies and multifunctionality. Nowadays, nanoparticles (NPs) have multiple applications in different branches of science. In recent years, NPs have repetitively been reported to play a significant role in modern medicine. They have been analyzed for different clinical applications, such as drug carriers, gene delivery to tumors, and contrast agents in imaging. A wide range of nanomaterials based on organic, inorganic, lipid, or glycan compounds, as well as on synthetic polymers has been utilized for the development and improvement of new cancer therapeutics. In this study, we discuss the role of NPs in treating cancer among different drug delivery methods for cancer therapy.
192 citations
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TL;DR: Analysis of the frequency of isolated bacteria according to the age of the patients revealed that Klebsiella infections are more prevalent in the older age groups and Pseudomonas infections aremore prevalent in children and the elderly.
191 citations
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26 Jul 2015TL;DR: Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress n eeds to be re-evaluated by experts.
Abstract: Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress n eeds to be re-evaluated by experts.
187 citations
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TL;DR: The possible effects of melatonin on diabetic retinopathy are reviewed, focusing on its ability to regulate autophagy processes, to determine its role in initiation and exacerbation of DR.
186 citations
Authors
Showing all 11569 results
Name | H-index | Papers | Citations |
---|---|---|---|
Theo Vos | 156 | 502 | 186409 |
Derrick A Bennett | 90 | 233 | 120764 |
Mohammad Abdollahi | 90 | 1045 | 35531 |
Albert Gjedde | 85 | 548 | 28653 |
Nassim Kamar | 73 | 628 | 20442 |
Nima Rezaei | 72 | 1215 | 26295 |
Alireza Khataee | 68 | 525 | 20805 |
William E. Acree | 66 | 958 | 21196 |
Mohammad Athar | 63 | 329 | 14384 |
Amir H. Mohammadi | 62 | 698 | 16044 |
Ali Montazeri | 61 | 625 | 17494 |
Ali Nokhodchi | 55 | 322 | 9087 |
Muhammad Naveed | 54 | 346 | 10376 |
Behrooz Z. Alizadeh | 52 | 189 | 13793 |
Mohammad Reza Zali | 51 | 804 | 12541 |