Institution
Tabriz University of Medical Sciences
Education•Tabriz, Iran•
About: Tabriz University of Medical Sciences is a education organization based out in Tabriz, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 11499 authors who have published 17525 publications receiving 241099 citations.
Topics: Population, Cancer, Medicine, Solubility, Randomized controlled trial
Papers published on a yearly basis
Papers
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TL;DR: Results revealed that both ethosome and transfersome formulations can act as drug reservoir in skin and extend the pharmacologic effects of Diclofenac sodium.
Abstract: The aim of this study was to improve the transdermal permeation of Diclofenac sodium, a poorly water-soluble drug, employing conventional liposomes, ethosomes, and transfersomes. The prepared formulations had been characterized for the loaded drug amount and vesicle size. The prepared vesicular systems were incorporated into 1% Carbopol 914 gel, and a survey of in vitro drug release and drug retention into rat skin has been done on them using a modified Franz diffusion cell. The cumulative amount of drug permeated after 24 h, flux, and permeability coefficient were assessed. Stability studies were performed for three months. The size of vesicles ranged from 145 to 202 nm, and the encapsulation efficiency of the Diclofenac sodium was obtained between 42.61% and 51.72%. The transfersomes and ethosomes provided a significantly higher amount of cumulative permeation, steady state flux, permeability coefficient, and residual drug into skin compared to the conventional liposomes, conventional gel, or hydroethanolic solution. The in vitro release data of all vesicular systems were well fit into Higuchi model (RSD > 0.99). Stability tests indicated that the vesicular formulations were stable over three months. Results revealed that both ethosome and transfersome formulations can act as drug reservoir in skin and extend the pharmacologic effects of Diclofenac sodium.
165 citations
TL;DR: Understanding molecular mechanisms behind extracellular vesicles related COVID-19 virus infection may provide us with an avenue to identify its entry, replication, spreading, and infection to overcome its adverse effects.
164 citations
TL;DR: There is a methodological issue regarding the study discussed in this letter, which affects the quality of the study and should be considered for publication.
Abstract: Dear editor,
We read with great interest the review entitled ‘Paracetamol vs other analgesia in adult patients with minor musculoskeletal injuries: a systematic review’,1 published in the Emergency Medicine Journal . Although the authors have stated that they followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, there is a methodological issue regarding the study discussed in this letter, which …
164 citations
TL;DR: Most studies have been in favor of the probiotics in the prevention or treatment of BV, and no adverse effects have been reported, so it may be helpful to recommend daily consumption of probiotic products to improve public health among women.
Abstract: ObjectiveBacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint
164 citations
TL;DR: Nano-curcumin, as an anti-inflammatory herbal based agent, may be able to modulate the increased rate of inflammatory cytokines especially IL-1β and IL-6 mRNA expression and cytokine secretion in COVID-19 patients, which may cause an improvement in clinical manifestation and overall recovery.
162 citations
Authors
Showing all 11569 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Theo Vos | 156 | 502 | 186409 |
| Derrick A Bennett | 90 | 233 | 120764 |
| Mohammad Abdollahi | 90 | 1045 | 35531 |
| Albert Gjedde | 85 | 548 | 28653 |
| Nassim Kamar | 73 | 628 | 20442 |
| Nima Rezaei | 72 | 1215 | 26295 |
| Alireza Khataee | 68 | 525 | 20805 |
| William E. Acree | 66 | 958 | 21196 |
| Mohammad Athar | 63 | 329 | 14384 |
| Amir H. Mohammadi | 62 | 698 | 16044 |
| Ali Montazeri | 61 | 625 | 17494 |
| Ali Nokhodchi | 55 | 322 | 9087 |
| Muhammad Naveed | 54 | 346 | 10376 |
| Behrooz Z. Alizadeh | 52 | 189 | 13793 |
| Mohammad Reza Zali | 51 | 804 | 12541 |