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Institution

Universidad del Desarrollo

EducationSantiago, Chile
About: Universidad del Desarrollo is a education organization based out in Santiago, Chile. It is known for research contribution in the topics: Population & Entrepreneurship. The organization has 2695 authors who have published 3578 publications receiving 52302 citations.


Papers
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Journal ArticleDOI
TL;DR: A learning curve was present, as most of the complications happened in the initial cases, and this is the largest reported series of proximal closing wedge osteotomy for hallux valgus deformities.
Abstract: Background:The proximal oblique sliding closing wedge osteotomy (POSCOW) technique was developed to address moderate to severe hallux valgus deformity. We present a retrospective multicenter study to analyze the midterm radiological and clinical outcomes of patients treated with this type of proximal osteotomy fixed with plates.Materials and Methods:One hundred and forty-four patients (187 feet) were operated on between May 2005 and June 2010 in 2 separate centers. Inclusion criteria were symptomatic moderate to severe incongruent hallux valgus deformity, no significant restriction in the first metatarsophalangeal joint movement, none to minimal degenerative changes in the first metatarsophalangeal or the tarsometatarsal joints, and no hypermobility. The median age was 60 years. The preoperative hallux valgus angle (HV) was 35.6 degrees, intermetatarsal angle (IM) was 15.3 degrees, AOFAS score was 53 points. The median follow-up was 35 months (range, 12-73). A POSCOW osteotomy was performed in all patient...

24 citations

Journal ArticleDOI
TL;DR: In this article, an econometric model is presented that identifies the main variables explaining evasion of fare payment on a public transport system using a cointegration approach, and the model parameters are estimated using data from the Santiago (Chile) bus system, where evasion has been measured at approximately 28%.
Abstract: An econometric model is presented that identifies the main variables explaining evasion of fare payment on a public transport system. The model uses a cointegration approach. The model parameters are estimated using data from the Santiago (Chile) bus system, where evasion has been measured at approximately 28%. The main results of the model are that (i) a 10% increase in the fare raises evasion by 2 percentage points and (ii) a 10% increase in inspections lowers evasion by 0.8 percentage points. An increase in unemployment, the third explanatory variable in the model, tends to induce a decrease in evasion, and vice versa. This counterintuitive finding may be explained by the fact that those most vulnerable to job loss, and more likely to evade than the average user due to economic necessity, tend to reduce their use of the bus system when unemployment rises and increase it when unemployment falls. Our results suggest a revision of the evasion control policy in Santiago to improve its effectiveness, and to link inspection efforts to fare increases or to decreases in unemployment.

24 citations

Journal ArticleDOI
TL;DR: Infiltrating syringomatous adenoma of the nipple is a rare, benign, locally invasive tumor with recurrence potential, showing sweat duct differentiation, which can clinically, radiologically and pathologically mimic cancer.
Abstract: Infiltrating syringomatous adenoma of the nipple is a rare, benign, locally invasive tumor with recurrence potential, showing sweat duct differentiation. It can clinically, radiologically and pathologically mimic cancer. Histopathologically, it must be distinguished from florid papillomatosis, adenosquamous carcinoma, adenoid cystic carcinoma and sclerosing syringomatous carcinoma. A 44-year-old woman presented with pain on the right nipple for 7 days. On physical exam there was an irregular nodule on nipple area with edema. The skin was intact. The ultrasound showed a hypoechoic irregular nodule measuring 7.5 mm in the nipple area. The mammography was unspecific. The lesion was surgically removed and histopathologically, the tumor was composed of ducts and tubules lined with a double-layered epithelial cells. The lining cells were small, cuboidal with a central nuclei and eosinophilic nuclei. The stroma was dense with lymphocytes and plasma cells, and compressed many of the ducts that contained a comma or tadpole-shape, giving an impression of a syringoma. Some ducts were slightly dilated with squamous metaplasia. Some of these cysts were connected with the overlying epidermis. Mitotic figures were rare and no pleomorfism or hyperchromasia was observed. At the periphery, the ducts invaded muscular fibers of the nipple. The surgical margins were free of neoplastic involvement. Patient has no signs of progression of disease in 1 year of follow-up.

24 citations

Journal ArticleDOI
12 Jan 2016-PLOS ONE
TL;DR: This is the first study analysing the spatial distribution of socioeconomic deprivation among international immigrants and the total population in a Latin American country and it showed that socioeconomically deprived immigrants tended to be concentrated in counties in the northern and central area of Chile.
Abstract: Introduction and Purpose of the Study Immigrants in Chile have diverse characteristics and include socioeconomically deprived populations. The location of socioeconomically deprived immigrants is important for the development of public policy intelligence at the local and national levels but their areas of residence have not been mapped in Chile. This study explored the spatial distribution of socioeconomic deprivation among immigrants in Chile, 1992–2012, and compared it to the total population. Material and Methods Areas with socioeconomically deprived populations were identified with a deprivation index which we developed modelled upon the Index of Multiple Deprivation (IMD) for England. Our IMD was based upon the indicators of unemployment, low educational level (primary) and disability from Census data at county level for the three decades 1992, 2002 and 2012, for 332, 339 and 343 counties respectively. We developed two versions of the IMD one based on disadvantage among the total population and another focused upon the circumstances of immigrants only. We generated a spatial representation of the IMD using GIS, for the overall IMD score and for each dimension of the index, separately. We also compared the immigrants´ IMD to the total population´s IMD using Pearson´s correlation test. Results Results showed that socioeconomically deprived immigrants tended to be concentrated in counties in the northern and central area of Chile, in particular within the Metropolitan Region of Santiago. These were the same counties where there was the greatest concentration of socioeconomic deprivation for the total population during the same time periods. Since 1992 there have been significant change in the location of the socioeconomically deprived populations within the Metropolitan Region of Santiago with the highest IMD scores for both the total population and immigrants becoming increasingly concentrated in the central and eastern counties of the Region. Conclusion This is the first study analysing the spatial distribution of socioeconomic deprivation among international immigrants and the total population in a Latin American country. Findings could inform policy makers about location of areas of higher need of social protection in Chile, for both immigrants and the total resident population in the country.

24 citations

Journal ArticleDOI
TL;DR: Because this class of autoantibody causes myelin sheath destruction in multiple sclerosis (MS), it is hypothesized that a similar pathological role for them in ASD is similar.

23 citations


Authors

Showing all 2724 results

NameH-indexPapersCitations
Joseph P. Broderick13050472779
Craig S. Anderson10165049331
Pierre Amarenco9741535259
Cynthia S. Crowson8845229703
Heinrich Mattle8440527581
Jaana Suvisaari7142431878
Charles S. Rabkin5917316858
Catterina Ferreccio5818921407
Julien Labreuche5217610553
José Mario Martínez5126314041
Kurt A. Schalper491488836
Cesar A. Arias482479344
Pablo M. Lavados3813520707
Carlo Giupponi372174621
Carlos Eyzaguirre351234625
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202312
202233
2021467
2020458
2019345
2018291