Institution
University of Health and Allied Sciences
Education•Ho, Ghana•
About: University of Health and Allied Sciences is a education organization based out in Ho, Ghana. It is known for research contribution in the topics: Population & Public health. The organization has 637 authors who have published 1063 publications receiving 9380 citations. The organization is also known as: UHAS & IAU-024335.
Papers
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TL;DR: Empirical evidence abounds that immune system modulation by estrogen protect females from severe inflammation and for that matter severe COVID-19, and possible therapeutic avenues including androgen deprivation therapy (ADT), estrogen-based therapy, and ACE inhibitors for consideration in the fight against CO VID-19 are explored.
34 citations
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TL;DR: The findings suggest that there is the need to examine the mental health of women living with breast cancer as part of the routine healthcare, and social support ties should be strengthened to improve their quality of life.
Abstract: Depression and anxiety are common mental health comorbidities found among women living with breast cancer. The presence of these mental health comorbidities results in decreased quality of life among patients. However, the indirect effects of depression and anxiety on quality of life have not been fully established. This study therefore examined the direct and indirect effects of depression and anxiety on quality of life through social support and religiosity. Using a cross-sectional survey, 205 purposively selected participants were administered measures of depression and anxiety, social support, religiosity and quality of life. The statistical package for the social sciences (SPSS) with PROCESS Macro was used for mediation analyses. Findings showed that there were significant direct negative effects of depression and anxiety on quality of life. Whereas depression had a significant negative indirect effect on quality of life through social support (b = − 0.247, 95% CI = − 0.482 to − 0.071), anxiety had a significant positive indirect effect on quality of life through social support (b = 0.142, 95%CI = 0.011 to 0.324). However, depression and anxiety did not have any significant indirect effect on quality of life through religiosity. These findings suggest that there is the need to examine the mental health of women living with breast cancer as part of the routine healthcare, and social support ties should be strengthened to improve their quality of life.
33 citations
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TL;DR: The findings suggest that the study region is of intermediate to high endemicity with hepatitis B infection, and generally, females are more likely to be HBsAg positive than males.
Abstract: The prevalence of transfusion associated hepatitis B virus infection varies across different geographical populations. Establishing the sero-prevalence of the disease is important to informing the direction of preventive and control strategies. We sought to estimate the sero-prevalence of hepatitis B surface antigen among blood donors in Ho Municipal Hospital, Ghana. This was a retrospective study which involved reviewing of blood donation records for the year 2014 in Ho Municipal Hospital. The records were analysed to determine the prevalence of hepatitis B virus among blood donors. Data analysis was done using STATA statistical package. A total of 576 blood donors were screened in 2014, out of which 520 (90%) were males and the rest females. The overall sero-prevalence of hepatitis B virus was 7.5% (95% CI 5.6–9.9%). The prevalence was highest (8.9%; 95% CI 5.6–14.0) among donors between 30 and 39 years old and among females (14.3%; 95% CI 7.4–25.7). Females were about 2.5 times more likely to be HBsAg positive compared with males (p < 0.05). The findings suggest that the study region is of intermediate to high endemicity with hepatitis B infection. Generally, females are more likely to be HBsAg positive than males. Planning more extensive screening and vaccination campaigns and educational programmes would help reduce the transmission of the infection among the general population.
33 citations
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University of London1, Makerere University2, Bandim Health Project3, Statens Serum Institut4, Aarhus University5, University of Gondar6, Kwame Nkrumah University of Science and Technology7, University of Health and Allied Sciences8, International Centre for Diarrhoeal Disease Research, Bangladesh9, Umeå University10, Centers for Disease Control and Prevention11
TL;DR: This large-scale study is the first randomised comparison of FBH+ and FPH to measure pregnancy outcomes in a household survey in five selected INDEPTH Network sites in Africa and South Asia to inform strategies to improve health and demographic surveillance capture of neonatal/child mortality and pregnancy outcomes.
Abstract: Background: Under-five and maternal mortality were halved in the Millennium Development Goals (MDG) era, with slower reductions for 2.6 million neonatal deaths and 2.6 million stillbirths. The Ever ...
33 citations
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TL;DR: Increased prenatal HAP exposure reduces CBMC mtDNAcn, suggesting cumulative prenatal oxidative stress injury, and an LPG stove intervention may reverse this effect.
Abstract: Background: Associations between prenatal household air pollution (HAP) exposure or cookstove intervention to reduce HAP and cord blood mononuclear cell (CBMC) mitochondrial deoxyribonucleic acid copy number (mtDNAcn), an oxidative stress biomarker, are unknown. Materials and Methods: Pregnant women were recruited and randomized to one of two cookstove interventions, including a clean-burning liquefied petroleum gas (LPG) stove, or control. Prenatal HAP exposure was determined by serial, personal carbon monoxide (CO) measurements. CBMC mtDNAcn was measured by quantitative polymerase chain reaction. Multivariable linear regression determined associations between prenatal CO and cookstove arm on mtDNAcn. Associations between mtDNAcn and birth outcomes and effect modification by infant sex were explored. Results: LPG users had the lowest CO exposures (p = 0.02 by ANOVA). In boys only, average prenatal CO was inversely associated with mtDNAcn (β = -14.84, SE = 6.41, p = 0.03, per 1ppm increase in CO). When examined by study arm, LPG cookstove had the opposite effect in all children (LPG β = 19.34, SE = 9.72, p = 0.049), but especially boys (β = 30.65, SE = 14.46, p = 0.04), as compared to Control. Increased mtDNAcn was associated with improved birth outcomes. Conclusions: Increased prenatal HAP exposure reduces CBMC mtDNAcn, suggesting cumulative prenatal oxidative stress injury. An LPG stove intervention may reverse this effect. Boys appear most susceptible.
32 citations
Authors
Showing all 642 results
Name | H-index | Papers | Citations |
---|---|---|---|
Christopher J L Murray | 209 | 754 | 310329 |
Fred Binka | 55 | 178 | 9536 |
Seth Owusu-Agyei | 52 | 276 | 10805 |
John O. Gyapong | 50 | 145 | 7813 |
Sake J. de Vlas | 50 | 226 | 8740 |
Mehdi Ahmadi | 48 | ||
Wim Groot | 47 | 377 | 8993 |
Abraham Hodgson | 46 | 131 | 6871 |
Milena Pavlova | 40 | 246 | 5372 |
Irene Akua Agyepong | 36 | 115 | 5006 |
Margaret Gyapong | 35 | 115 | 3307 |
Abraham Oduro | 35 | 155 | 3539 |
Said Aboud | 35 | 184 | 3819 |
David Guwatudde | 28 | 96 | 2789 |
Billy Ngasala | 27 | 68 | 2552 |