Institution
University of Health and Allied Sciences
Education•Ho, Ghana•
About: University of Health and Allied Sciences is a education organization based out in Ho, Ghana. It is known for research contribution in the topics: Population & Public health. The organization has 637 authors who have published 1063 publications receiving 9380 citations. The organization is also known as: UHAS & IAU-024335.
Papers
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International Institute for Population Sciences1, World Health Organization2, University of Minnesota3, University of Oregon4, Vassar College5, University of Ghana6, Russian Academy7, Centers for Disease Control and Prevention8, University of Cape Town9, Northwestern University10, University of Health and Allied Sciences11, University of Notre Dame12, Umeå University13, University of Sydney14, Capital Medical University15, University of Newcastle16, National Research Council17
TL;DR: Algorithm/measured test-based prevalence of NCDs was much higher than self-reported prevalence in all 6 countries, indicating underestimation of NCS prevalence in low- and middle-income countries and highlighting the inadequacies in diagnosis and management of N CDs in local health-care systems.
Abstract: In this paper, we examine patterns of self-reported diagnosis of noncommunicable diseases (NCDs) and prevalences of algorithm/measured test-based, undiagnosed, and untreated NCDs in China, Ghana, India, Mexico, Russia, and South Africa. Nationally representative samples of older adults aged ≥50 years were analyzed from wave 1 of the World Health Organization's Study on Global Ageing and Adult Health (2007-2010; n = 34,149). Analyses focused on 6 conditions: angina, arthritis, asthma, chronic lung disease, depression, and hypertension. Outcomes for these NCDs were: 1) self-reported disease, 2) algorithm/measured test-based disease, 3) undiagnosed disease, and 4) untreated disease. Algorithm/measured test-based prevalence of NCDs was much higher than self-reported prevalence in all 6 countries, indicating underestimation of NCD prevalence in low- and middle-income countries. Undiagnosed prevalence of NCDs was highest for hypertension, ranging from 19.7% (95% confidence interval (CI): 18.1, 21.3) in India to 49.6% (95% CI: 46.2, 53.0) in South Africa. The proportion untreated among all diseases was highest for depression, ranging from 69.5% (95% CI: 57.1, 81.9) in South Africa to 93.2% (95% CI: 90.1, 95.7) in India. Higher levels of education and wealth significantly reduced the odds of an undiagnosed condition and untreated morbidity. A high prevalence of undiagnosed NCDs and an even higher proportion of untreated NCDs highlights the inadequacies in diagnosis and management of NCDs in local health-care systems.
139 citations
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Lagos State University1, University of Pretoria2, Healthcare Improvement Scotland3, University of Glasgow4, University of Belgrade5, University of Botswana6, University of Adelaide7, University of Bamenda8, Memorial Hospital of South Bend9, University of Ghana10, University of Health and Allied Sciences11, University of Nairobi12, University of KwaZulu-Natal13, University of Malawi14, University of Namibia15, Ekiti State University16, University of Pittsburgh17, Sefako Makgatho Health Sciences University18, Qassim University19, University of Khartoum20, Egerton University21, University of Zambia22, College of Health Sciences, Bahrain23, University of Zimbabwe24, University of London25, University of Liverpool26, University of Verona27, Jagiellonian University Medical College28, Hawler Medical University29, Strathclyde Institute of Pharmacy and Biomedical Sciences30, University of Manchester31, RMIT University32, Hanoi University33
TL;DR: There are multiple activities across Africa to reduce the spread of COVID-19 and address misinformation, which can have catastrophic consequences, assisted by the WHO and others, which appear to be working in a number of countries.
Abstract: Background The COVID-19 pandemic has already claimed considerable lives. There are major concerns in Africa due to existing high prevalence rates for both infectious and non-infectious diseases and limited resources in terms of personnel, beds and equipment. Alongside this, concerns that lockdown and other measures will have on prevention and management of other infectious diseases and non-communicable diseases (NCDs). NCDs are an increasing issue with rising morbidity and mortality rates. The World Health Organization (WHO) warns that a lack of nets and treatment could result in up to 18 million additional cases of malaria and up to 30,000 additional deaths in sub-Saharan Africa. Objective Document current prevalence and mortality rates from COVID-19 alongside economic and other measures to reduce its spread and impact across Africa. In addition, suggested ways forward among all key stakeholder groups. Our approach Contextualise the findings from a wide range of publications including internet-based publications coupled with input from senior-level personnel. Ongoing activities Prevalence and mortality rates are currently lower in Africa than among several Western countries and the USA. This could be due to a number of factors including early instigation of lockdown and border closures, the younger age of the population, lack of robust reporting systems and as yet unidentified genetic and other factors. Innovation is accelerating to address concerns with available equipment. There are ongoing steps to address the level of misinformation and its consequences including fines. There are also ongoing initiatives across Africa to start addressing the unintended consequences of COVID-19 activities including lockdown measures and their impact on NCDs including the likely rise in mental health disorders, exacerbated by increasing stigma associated with COVID-19. Strategies include extending prescription lengths, telemedicine and encouraging vaccination. However, these need to be accelerated to prevent increased morbidity and mortality. Conclusion There are multiple activities across Africa to reduce the spread of COVID-19 and address misinformation, which can have catastrophic consequences, assisted by the WHO and others, which appear to be working in a number of countries. Research is ongoing to clarify the unintended consequences given ongoing concerns to guide future activities. Countries are learning from each other.
137 citations
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TL;DR: The Navrongo health and demographic surveillance system (NHDSS) as mentioned in this paper is one of the three research centres of the Ghana health service, which is used for collaborative research.
Abstract: Located in the Kassena-Nankana districts of northern Ghana, the Navrongo health and demographic surveillance system (NHDSS) was established in 1992 by the Navrongo health research centre (NHRC). The NHRC is one of three research centres of the Ghana health service. The activities and potential of the NHDSS for collaborative research are described. The NHDSS monitors health and demographic dynamics of the two Kassena-Nankana districts of northern Ghana and facilitates evaluation of the morbidity and mortality impact of health and social interventions. The total population currently under surveillance is 152 000 residing in 32 000 households. Events monitored routinely include pregnancies, births, morbidity, deaths, migration, marriages and vaccination coverage. Data updates are done every 4 months by trained fieldworkers. The NHRC also undertakes biomedical and socio-economic studies. Additional features of the NHDSS include the community key informant system where trained volunteers routinely report key events, such as births and deaths as they occur in their locality and the verbal autopsy (VA) system for determining the probable causes of deaths that occur at the community level. Data from the NHDSS are shared with funders and collaborators and partners in the INDEPTH Network. The Director of the NHDSS is the contact person for potential collaboration with the NHDSS and the use of its data.
127 citations
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TL;DR: Skin microfilarial loads are lower after moxidECTin treatment than after ivermectin treatment, and Moxidectin would be expected to reduce parasite transmission between treatment rounds more than iverMectin could, thus accelerating progress towards elimination.
124 citations
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Imperial College London1, Swiss Tropical and Public Health Institute2, University of Basel3, University of London4, Karolinska Institutet5, University of Notre Dame6, Walter and Eliza Hall Institute of Medical Research7, University of Melbourne8, Pasteur Institute9, Radboud University Nijmegen10, Addis Ababa University11, PATH12, Wellcome Trust Centre for Human Genetics13, University of Oxford14, University of Health and Allied Sciences15, University of Paris16, University of the Sciences17, University of Ghana18, Centers for Disease Control and Prevention19, National Institute for Medical Research20, University of California, San Francisco21, Dar es Salaam University College of Education22, University of Edinburgh23, Mahidol University24
TL;DR: Results indicate that subpatent infections contribute to the infectious reservoir, may be long lasting, and require more sensitive diagnostics to detect them in lower transmission settings.
Abstract: Malaria infections occurring below the limit of detection of standard diagnostics are common in all endemic settings. However, key questions remain surrounding their contribution to sustaining transmission and whether they need to be detected and targeted to achieve malaria elimination. In this study we analyse a range of malaria datasets to quantify the density, detectability, course of infection and infectiousness of subpatent infections. Asymptomatically infected individuals have lower parasite densities on average in low transmission settings compared to individuals in higher transmission settings. In cohort studies, subpatent infections are found to be predictive of future periods of patent infection and in membrane feeding studies, individuals infected with subpatent asexual parasite densities are found to be approximately a third as infectious to mosquitoes as individuals with patent (asexual parasite) infection. These results indicate that subpatent infections contribute to the infectious reservoir, may be long lasting, and require more sensitive diagnostics to detect them in lower transmission settings.
121 citations
Authors
Showing all 642 results
Name | H-index | Papers | Citations |
---|---|---|---|
Christopher J L Murray | 209 | 754 | 310329 |
Fred Binka | 55 | 178 | 9536 |
Seth Owusu-Agyei | 52 | 276 | 10805 |
John O. Gyapong | 50 | 145 | 7813 |
Sake J. de Vlas | 50 | 226 | 8740 |
Mehdi Ahmadi | 48 | ||
Wim Groot | 47 | 377 | 8993 |
Abraham Hodgson | 46 | 131 | 6871 |
Milena Pavlova | 40 | 246 | 5372 |
Irene Akua Agyepong | 36 | 115 | 5006 |
Margaret Gyapong | 35 | 115 | 3307 |
Abraham Oduro | 35 | 155 | 3539 |
Said Aboud | 35 | 184 | 3819 |
David Guwatudde | 28 | 96 | 2789 |
Billy Ngasala | 27 | 68 | 2552 |