University of the Philippines Manila

About: University of the Philippines Manila is a education organization based out in Manila, Philippines. It is known for research contribution in the topics: Population & Medicine. The organization has 2218 authors who have published 2357 publications receiving 88781 citations. The organization is also known as: UPM.

Coordination of international multicenter studies: governance and administrative structure

Abstract: A well-conducted multicenter study needs to assure standardization, uniformity of procedures, high data quality, and collaboration across sites. This manuscript describes the organization and dynamics of multicenter studies, focusing on governance and administrative structures among countries of diverse cultures. The organizational structure of a multicenter study is described, and a system for oversight and coordination, along with roles and responsibilities of participants in the multicenter study, are presented. The elements of a governance document are also reviewed, along with guidelines and policies for effective collaboration. The experience of an ongoing multi-country collaboration, the World Studies of Abuse in the Family Environment (WorldSAFE), illustrates the implementation of these guidelines. It is essential that multicenter studies have an objective coordinating center and that the investigators jointly develop a written governance document to enable collaboration and preserve collegiality among participating investigators.

Corrigendum to “Systematic Review of Oncological Outcomes Following Surgical Management of Localised Renal Cancer” [Eur Urol 2012;61:972–93]

Abstract: Steven MacLennan , Mari Imamura , Marie C. Lapitan , Muhammad Imran Omar , Thomas B.L. Lam , Ana M. Hilvano-Cabungcal , Pam Royle , Fiona Stewart , Graeme MacLennan , Sara J. MacLennan , Steven E. Canfield , Sam McClinton , T.R. Leyshon Griffiths , Börje Ljungberg , James N’Dow *, UCAN Systematic Review Reference Group and the EAU Renal Cancer Guideline Panel a Academic Urology Unit, University of Aberdeen, Aberdeen, UK; b University of the Philippines-Manila, Manila, Philippines; c Department of Urology, Aberdeen Royal Infirmary, Aberdeen, UK; d Department of Public Health, University of Aberdeen, UK; e Health Services Research Unit, University of Aberdeen, UK; f Division of Urology, University of Texas Medical School at Houston, Houston, TX, USA; g Department of Urology, University Hospitals of Leicester NHS Trust, Leicester General Hospital, Leicester, UK; h Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå, University, Umeå, Sweden

Genotype Analysis of Hepatitis C Virus among Blood Donors and Inmates in Metro Manila, The Philippines

Abstract: Antibodies against hepatitis C virus (HCV) were detected in 18 (2.3%) of 800 sera from commercial blood donors and 23 (4.6%) of 502 sera from inmates in Metro Manila, the Philippines. The difference in the antibody prevalence between the two groups was statistically significant (P<0.05). HCV RNA was detected in 14 (78%) of the 18 antibody-positive sera from blood donors and 19 (83%) of the 23 antibody-positive sera from inmates. Genotype analysis revealed that HCV-1b (50%) was most common among blood donors, followed by HCV-1a (36%) and HCV-2a (7%). Among inmates, on the other hand, HCV-1a (68%) was most common, followed by HCV-1b (11%), HCV-2a (5%) and HCV-2b (5%). Overall, HCV-1a and HCV-1b appeared to be predominant among them. Thus, the genotype prevalence in the Philippines was distinct from those in other Southeast Asian countries such as Thailand, Vietnam and Indonesia, and also distinct from those in the Far East including Taiwan, Mainland China and Japan.