Showing papers by "Yonsei University published in 1993"
TL;DR: The results showed that the mineral trioxide aggregate had significantly less leakage than IRM or amalgam (p < 0.05) while IRM showed the least underfilling tendency.
847 citations
TL;DR: T careful preoperative planning is recommended, with the use of a contemporary cemented technique when a satisfactory fit cannot be obtained, for primary total hip arthroplasty using an uncemented porous-coated anatomic hip.
Abstract: We studied 108 patients (116 hips) who were followed for a minimum of six years (73 to 89 months) after primary total hip arthroplasty using an uncemented porous-coated anatomic hip. The average age of the patients at operation was 48.4 years, and the diagnosis was avascular necrosis of the femoral head in 46 hips, neglected femoral neck fracture in 27, osteoarthritis secondary to childhood pyogenic arthritis in 24 and to childhood tuberculous arthritis in five, and miscellaneous in 14. The average preoperative Harris hip score was 55, which improved to 91 at latest follow-up. All patients with loose femoral components or disabling thigh pain had received prostheses which were undersized in the coronal or the sagittal plane, or in both. No patient with a satisfactory fit in both coronal and sagittal planes had loosening of the femoral component or disabling thigh pain. Three acetabular components showed aseptic loosening and 20 showed excessive wear (5 to 11 mm) of the polyethylene liner. Excessive wear was related to young age, but not to body-weight, gender, primary diagnosis, hip score, or range of hip movement. There was a high incidence of osteolysis (38 of 116 hips, 33%). We recommend careful preoperative planning, with the use of a contemporary cemented technique when a satisfactory fit cannot be obtained. The high incidence of excessive wear and of osteolysis needs further investigation.
266 citations
TL;DR: In this article, a new formulation of QCD sum rules at finite temperature (T) is developed, where all the soft dynamics including the effect of finite T in the hadronic phase is taken into account in the thermal average of local operators.
150 citations
TL;DR: The histologic features and diagnostic pitfalls are discussed, as well as the need to consider the clinical, radiographic, and microscopic features in arriving at a final diagnosis.
146 citations
TL;DR: In this paper, the authors investigated the possibility of speculation having caused the prices of land and housing to deviate from their given long-run equilibrium levels in Korea and Japan, and they modeled speculation by incorporating the expected future price into the demand equation.
Abstract: This article investigates the possibility of speculation having caused the prices of land and housing to deviate from their given long-run equilibrium levels in Korea and Japan. We modeled speculation by incorporating the expected future price into the demand equation. The existence of growing rational bubbles was tested on Korean and Japanese data using the standard econometric technique for estimating linear rational expectations models. Our analysis of the Korean annual data suggests that a growing rationale bubble existed during the 1974–1989 period, nominal or real. Estimation results of the same model using Japanese annual data also confirmed the existence of a bubble in land price. Contrary to our analysis of land price data, the evidence of the bubble was much less obvious in Korean annual housing price data. We therefore estimated the model using quarterly data and found that the existence of a bubble could not be established in housing prices. This finding was also consistent with the trend of the rent-to-value ratio series in apartment units. Our results need to be taken with caution because our approach suffers from the common econometric problem of possible mis-specification of the model and because of the small size of the sample.
89 citations
TL;DR: It is felt that a more extensive resection procedure than cartilage shaving should be considered, even in patients with superficial tracheal invasion, to increase the diseasefree survival rate.
Abstract: This study was carried out to ascertain whether the cartilage-shaving procedure is appropriate to control thyroid carcinoma with tracheal cartilage invasion. Of 432 thyroid carcinoma patients treated between 1979 and 1988, 16 had tracheal cartilage invasion only. This patient population was made up of 3 men and 13 women, with a mean age of 55.8 years. Fourteen were diagnosed histologically as having papillary carcinoma and the remaining two as having follicular carcinoma. Cartilage shaving was the primary treatment in all the patients, and subsequent radioactive iodine (131I) or external-beam radiotherapy was administered to control any possible residual disease. Lifelong thyroid hormone replacement was instituted in all patients, and the follow-up period averaged 70.7 months. Only four of the 16 patients remained disease free; the disease was not controlled in the other 12, and seven of this latter group eventually died of their disease. We feel that a more extensive resection procedure than cartilage shaving should be considered, even in patients with superficial tracheal invasion, to increase the disease-free survival rate.
81 citations
TL;DR: In this article, lead magnesium niobate (Pb(Mg1/3Nb2/3)O3, PMN) was prepared by a molten salt synthesis method and powder characteristics were greatly influenced by the processing parameters, such as amount of salt, species of salt and the presence of excess PbO.
Abstract: Lead magnesium niobate (Pb(Mg1/3Nb2/3)O3, PMN) was prepared by a molten salt synthesis method. Powder characteristics were greatly influenced by the processing parameters, such as amount of salt, species of salt, and the presence of excess PbO. Grown in sulfate salts, PMN crystallites showed faceted morphology with a bimodal particle-size distribution in which the smaller particles were in the submicrometer range. The presence of excess PbO in the sulfate salts greatly influenced the faceted morphology and resulted in rounded PMN crystallites. The possible origin of particle morphology changes due to the processing parameters is discussed.
77 citations
TL;DR: It is demonstrated that the combined serotonin 5-HT2 and dopamine-D2 antagonist risperidone is an antipsychotic as potent as haloperidol and is better tolerated than haloperodol.
Abstract: A parallel group double-blind comparative trial was conducted to study the efficacy and safety of risperidone compared with haloperidol. After a one-week wash-out, 35 chronic schizophrenic patients (17 males, 18 females) were randomly assigned to one of two groups for eight weeks of double-blind treatment. The patients' psychopathology was assessed by means of the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) and the Clinical Global Impression (CGI). Safety assessments included the Extrapyramidal Symptom Rating Scale (ESRS), the UKU Side Effect Rating Scale, vital signs, body weight, ECG and laboratory screening. Thirty-two patients completed the trial: there were 3 dropouts in the risperidone group. The results on the PANSS and CGI indicate that the mean changes from baseline on the total PANSS score and on the total BPRS score were comparable in both treatment groups. The number of patients where a clinical improvement at least 20% reduction in baseline score was also similar in both treatment groups. Risperidone caused less extrapyramidal symptoms and less side effects in UKU scale than haloperidol. No significant ECG changes were induced, no relevant changes in blood pressure or clinical laboratory parameters were observed. This study has demonstrated that the combined serotonin 5-HT2 and dopamine-D2 antagonist risperidone is an antipsychotic as potent as haloperidol. Risperidone causes less extrapyramidal symptoms, and is better tolerated than haloperidol.
73 citations
TL;DR: In this paper, the occurrence of sidechains of pectins in the plant cell walls is discussed in conjunction with their structural features with respect to chemical constituents and distribution, with particular emphasis on gelling and rheological properties.
64 citations
TL;DR: Transdermal dihydrotestosterone therapy is an effective and relatively safe modality in the treatment of microphallus and responses were noted in 4 patients who had failed testosterone therapy for microPHallus.
63 citations
TL;DR: In this paper, the movement of the Co-rich binder phase and its interaction with growing diamond particles during deposition were investigated by repeated observations of the same site on a WC-Co substrate surface.
TL;DR: Early instability of the femoral component measured by radiographs was correlated with and predictive of late radiographic loosening of the Femoral component of the PCA hip system.
Abstract: Primary total hip arthroplasties were performed in 108 patients (116 hips) using a porous coated anatomic (PCA) hip system. Nineteen (22 hips) of 108 patients (116 hips) who had a subsidence of a PCA femoral stem more than 3 mm were studied for the time onset, the amount of stem subsidence, and outcomes. A minimum follow-up period was seven years. The average age of the patients at operation was 37.4 years. The operative diagnosis was avascular necrosis of femoral head in seven hips; osteoarthrosis secondary to childhood septic hip joint in six; fracture of femoral neck in three; and miscellaneous in six hips. The average preoperative Harris hip score was 57 points, which improved to 82 points at the seven-year follow-up examination. Overall, there was a 79% prevalence of thigh pain (15 patients). Six patients had occasional, nondisabling, activity-related thigh pain. The remaining nine patients had persistent and disabling thigh pain at the final follow-up examination. All stems had an undersized component in one or both planes. One hip was stabilized by bone ingrowth. Twelve hips were fixed by fibrous tissue ingrowth and had occasional clinical symptoms. Nine hips had component loosening at the final follow-up examination, of which four were revised and five were pending revision. Early instability of the femoral component measured by radiographs was correlated with and predictive of late radiographic loosening of the femoral component.
01 Dec 1993
TL;DR: In this article, a jet stream entering a crossflow was investigated for injection through a single hole and an array of holes for blowing rates of 0.2 to 2.2.
Abstract: A jet stream entering a crossflow is investigated for injection through a single hole and an array of holes for blowing rates of 0.2 to 2.2. The naphthalene sublimation technique has been employed to study the local mass (heat) transfer in the injection hold and in the vicinity of the hole entrance. The Sherwood number is fairly uniform along the circumference of the inside hole surface even at the low blowing rate considered. This is quite different from the case without injection (zero blowing rate), when the Sherwood number is highly nonuniform. The transfer rate in the hole is weakly influenced by the crossflow and the zone, which is directly affected, is confined close to the hole exit (about 0.15 hole diameter in depth). The average Sherwood number is similar to that in the absence of crossflow except at low blowing rates. The Sherwood numbers on the hole entrance surface (backside) are the same as when there is no crossflow. Thus, the Sherwood numbers inside the hole and on the back surface can be closely approximated from experiments without crossflow.
TL;DR: PCR seemed to have an advantage over microscopic examination in detecting M. leprae in biopsy specimens negative for acid-fast bacilli, and even a sample with only one organism gave a PCR positive result.
Abstract: Biopsy specimens were obtained from 102 leprosy patients before chemotherapy and examined by polymerase chain reaction (PCR) using the primers amplifying the 372-bp DNA of a repetitive sequence of Mycobacterium leprae. The PCR results were then compared with bacterial indices (BI) of slit-skin smears and biopsy specimens. The intensities of DNA bands were in general correlated with the numbers of acid-fast bacilli, and even a sample with only one organism gave a PCR positive result. Ten 5-micron sections from each frozen tissue sample were pooled and processed for DNA preparation. PCR was positive for 11 (73.3%) of 15 biopsy specimens with BI of 0 determined for the paraffin sections from the same biopsy samples. PCR also gave positive results for 84 (96.6%) of 87 BI positive biopsy samples. Although the difference in overall results between the two methods was not statistically significant, PCR seemed to have an advantage over microscopic examination in detecting M. leprae in biopsy specimens negative for acid-fast bacilli. Further evaluation of PCR using more specimens from leprosy patients who are bacteriologically negative is warranted to ensure PCR's advantage over the conventional microscopic examination for the diagnosis of leprosy.
TL;DR: The International Organization for Standardization (ISO) developed an international size labelling system as discussed by the authors, which was used in several countries. But the way of labelling garment sizes has varied from one sizing system to another; most of the sizing systems classified figure types by height and drop value (the difference between hip girth and bust girth measurements), and the manner of classifying garments and the key dimensions of garment types in each system was slightly different.
Abstract: Reviews the sizing systems developed in several countries — the USA, Austria, England, Germany, Hungary, Japan and South Korea. A comparison of these systems shows that: the way of labelling garment sizes has varied from one sizing system to another; most of the sizing systems classified figure types by height and drop value (the difference between hip girth and bust girth measurements), and the way of classifying garments and the key dimensions of garment types in each system was slightly different. Recognizing the need for greater uniformity, the International Organization for Standardization (ISO) developed an international size labelling system. Many countries, including England, Japan, South Korea and Hungary, revised their size labelling systems by adopting the ISO system.
TL;DR: A systematic study of different exons of the PBGD gene from a large number of unrelated patients found a single base mutation, C to T, at position 346 of the sequence coding for PBGD was observed in 15 Dutch families but in only 1 French family.
Abstract: Acute intermittent porphyria (AIP) is an autosomal dominant disease characterized by a deficiency of porphobilinogen deaminase (PBGD). Up to now 14 different mutations have been described. In an effort to investigate the molecular epidemiology of AIP we have undertaken a systematic study of different exons of the PBGD gene from a large number of unrelated patients. Here, exon 8 from 82 unrelated Dutch and French AIP patients was examined using single strand confirmation polymorphism analysis (SSCP) after polymerase chain reaction (PCR) amplification. A single base mutation, C to T, at position 346 of the sequence coding for PBGD was observed in 15 Dutch families but in only 1 French family. A simple PCR assay is described to facilitate the diagnosis of this common mutation at the DNA level.
TL;DR: The hypothesis that a decrease in the antibody-mediated cytotoxicity against melanocytes may play a role in the improvement of vitiliginous lesions after systemic steroid treatment is supported.
TL;DR: There seemed to be a significant correlation between the cerebral white matter changes in the initial CT scan and the development of delayed neurologic sequelae after acute CO poisoning, particularly in middle age or older patients, but no correlation betweenThe CT findings and the clinical outcome of delayed neurological sequelae.
Abstract: Of 129 patients with carbon monoxide (CO) poisoning, 62(48.0%) had characteristic computed tomographic (CT) findings. The most common finding, seen in 42 patients, was low-density in the cerebral white matter, and the second characteristic feature, seen in 33 patients, was low-density in both globus pallidi. Abnormal CT findings tended to increase in accordance with the duration of unconsciousness during acute CO poisoning, but such findings occurred even when the mental state was clear during acute illness. The prognosis of acute CO poisoning depended on low-density lesions of the cerebral white matter rather than those of the globus pallidus. There also seemed to be a significant correlation between the cerebral white matter changes in the initial CT scan and the development of delayed neurologic sequelae after acute CO poisoning, particularly in middle age or older patients, but no correlation between the CT findings and the clinical outcome of delayed neurologic sequelae.
TL;DR: It is deemed that the endurance and strength of the upper body and the cardiac fitness for spinal cord-injured paraplegics may be improved by the wheelchair ergometer exercise.
Abstract: The purpose of this study was to investigate the effect of wheelchair ergometer training on spinal cord-injured paraplegics. Eleven male paraplegics with a mean age of 30.9 years (range, 20 to 49 years) participated in the wheelchair ergometer training for the period of 5 weeks. The mean peak heart rate, the mean peak systolic blood pressure and the mean time required for 100m wheelchair propelling at resistance level 1 were significantly decreased at the end of 5 weeks of training as compared with those at pre-training. There was no statistically significant difference in pulmonary function test at pre- and post-training. The peak torque of shoulder flexor and the total work of shoulder flexor and extensor at 180 degrees/sec after training were increased more significantly than those prior to the training. In accordance with the findings as revealed above, it is deemed that the endurance and strength of the upper body and the cardiac fitness for spinal cord-injured paraplegics may be improved by the wheelchair ergometer exercise.
TL;DR: In this article, a series of samples in the Gd1-xSrxCoO3-y (x = 0.00, 0.25 and 1.00) system with perovskite-type oxide have been prepared at 1200°C under an atmosphere with and without oxygen gas flow.
TL;DR: Results show that plasma levels of ethanol are lower when the ethanol is administered orally with ginseng than when it is administered alone, but that orally administered gins Fengseng has no effect on plasma Levels of ethanol administered intraperitoneally.
Abstract: The effect of red ginseng extract on the disposition of ethanol was studied in male Fischer 344 rats. Blood was drawn from the tail vein before and at 0.5, 1, 2, 3, 4, and 5 hours after dosing rats orally with aqueous ginseng (200 mg/kg), or an equivalent volume of water, followed immediately by 50% ethanol orally (3.2 g/kg) or intraperitoneally (1.5 g/kg). When the ethanol was administered orally, the mean area under the plasma concentration-time curve (0-->5 h) of ethanol was 21.0% less in the ginseng-treated rats than in the control rats. When the ethanol was administered intraperitoneally, there was no significant difference between ginseng-treated and control rats in area under the plasma concentration-time curve. The results show that plasma levels of ethanol are lower when the ethanol is administered orally with ginseng than when it is administered alone, but that orally administered ginseng has no effect on plasma levels of ethanol administered intraperitoneally.
TL;DR: The purpose of the investigation was to assess peripheral lymphocyte subpopulations in Koreans with actively spreading vitiligo.
Abstract: Background. An immune-mediated destruction of melanocytes is the most popular current theory of vitiligo. There have been a few published reports on the assessment of lymphocyte population in vitiligo, and they showed mixed results. The purpose of our investigation was to assess peripheral lymphocyte subpopulations in Koreans with actively spreading vitiligo.
Methods. Fifty patients with actively spreading vitiligo and 30 normal persons were studied for peripheral blood lymphocyte imbalance using flow cytometry. The percentages of total T-lymphocytes, B-lymphocytes, helper T cells, suppressor T cells, and natural killer cells were evaluated with the use of CD3, CD19, CD4, CD8, and CD16 monoclonal antibodies, respectively.
Results. The mean value of helper T cells showed a significant difference between the two groups with the value being 38.2% in patients and 43.5% in control subjects. Seventeen of the 50 patients showed reversed helper/suppressor T cell ratio, whereas only 1 of 30 control subjects showed reversed ratio. There was a statistically significant difference in the mean percentage of helper T cells and suppressor T cells between generalized vitiligo patients and control subjects. The percentage of B cells in patients with recent onset less than 1 year was higher than control subjects and patients with late onset. The mean percentage of natural killer cells was increased significantly in patients with negative autoantibody test.
Conclusions. The present data show that immunologic abnormalities, both cellular and humoral, are involved in the pathogenesis of vitiligo.
TL;DR: In this article, a food drying process in tunnel dryer was modeled from Keey's drying model and experimental drying curve, and optimized in operating conditions consisting of inlet air temperature, air recycle ratio and air flow rate.
Abstract: Food drying process in tunnel dryer was modeled from Keey's drying model and experimental drying curve, and optimized in operating conditions consisting of inlet air temperature, air recycle ratio and air flow rate. Radish was chosen as a typical food material to be dried, because it has a typical drying characteristics of food and quality indexes of ascorbic acid destruction and browning in the drying. Stricter quality retention constraint required higher energy consumption in minimizing the objective function of energy consumption under constraints of dried food quality. Optimization results of cocurrent and counter current tunnel drying showed higher inlet air temperature, lower recycle ratio and higher air flow rate with shorter total drying time. Compared with cocurrent operation counter current drying used lower air temperature, lower recycle ratio and lower air flow rate, and appeared to be more efficient in energy usage. Most of consumed energy was analyzed to be used for air heating and ...
TL;DR: Both direct and indirect immunofluorescence (the latter was performed on two occasions) were negative for all immunoreactants.
Abstract: Siu, In October 1991, a 4(i-year-old Cauca.sian woman took norfloxacin 400 mg twice daily for 7 days, lor a urinary tract infection. As she completed the course of treatment she noticed an itchy rash on her back and abdomen. The rash consisted of profuse, clustered vesicles on an inflanimiitory base, predominantly localized to the lower back, infraniammary areas and abdomen. There were no bucca! iesion,s. Two weeks after its onset the eruption changed in character and became pustular. Histopathology showed intraepidermal bullae with acantholysis. and a mixed perivascular infiltrate of lymphocytes, histiocytes and neutrophils (Fig, 1), Both direct and indirect immunofluorescence (the latter was performed on two occasions) were negative for all immunoreactants.
TL;DR: Despite diagnostic and therapeutic advances in the management of liver abscess, the prognosis has not improved in the 1980s as compared to the 1970s and may reflect an increase in the incidence of Liver abscess in old aged patients and patients with diabetes mellitus or underlying malignancy in the1980s.
Abstract: The diagnostic and treatment modalities of liver abscess have developed rapidly over the past few years but morbidity and mortality has not been markedly reduced. A total of 482 cases of liver abscess admitted to the Yonsei Medical Center over the past 20 years (Jan. 1971-Dec. 1990) were divided into 261 cases from the 1970s and 221 cases from the 1980s and the clinical and laboratory parameters were analyzed comparatively to determine if the clinical features, therapies and prognosis of liver abscess had changed. The proportion of amebic relative to pyogenic liver abscess decreased. Transbiliary infections increased in pyogenic liver abscess of the 1980s. Clinical signs such as jaundice and hepatomegaly and symptom duration before admission decreased. Abnormal laboratory features including hypoalbuminemia and elevation of alkaline phosphatase decreased and increased, respectively, in the 1980s. Ultrasonically guided percutaneous aspiration was the choice of treatment instead of surgical drainage in the 1980s. Despite diagnostic and therapeutic advances in the management of liver abscess, the prognosis has not improved in the 1980s as compared to the 1970s. This may reflect an increase in the incidence of liver abscess in old aged patients and patients with diabetes mellitus or underlying malignancy in the 1980s.
TL;DR: Cimetidine is an H2‐receptor antagonist which is mainly used to treat gastrointestinal diseases and has suggested that cimetidine has the ability to reverse acquired tolerance to dinitrochlorobenzene (DNCB).
Abstract: Cimetidine is an H2-receptor antagonist which is mainly used to treat gastrointestinal diseases. Recently, many authors have suggested that cimetidine has the ability to reverse acquired tolerance to dinitrochlorobenzene (DNCB).
We have used cimetidine in six patients with verruca plana who showed no therapeutic response to DNCB. Four of them responded and showed complete disappearance of the verruca plana. The mean duration of oral cimetidine administration (1.2 g/day) was 4 weeks until the disappearance. Therefore, we suggest that oral cimetidine can be used as an effective and safe adjunctive modality for the treatment of verruca plana.
TL;DR: The experience with 189 scrub typhus patients seen at a civilian outpatient clinic in Chinhae, Republic of Korea from 1985 through 1990 is reported, and the accuracy of clinical diagnosis by serologic tests is verified.
Abstract: Scrub typhus became a well recognized infectious disease threat to military operations in the Pacific Theater during World War II. Early diagnosis and treatment with tetracycline or chloramphenicol dramatically reduces the mortality and morbidity of this disease. Korea is a newly recognized scrub typhus endemic country. We report our experience with 189 scrub typhus patients seen at a civilian outpatient clinic in Chinhae, Republic of Korea, from 1985 through 1990, and verify the accuracy of clinical diagnosis by serologic tests.
TL;DR: In this paper, a comparison of the growth hormone response to l-dopa with or without pyridostigmine (inhibitor of acetylcholinesterase) pretreatment and insulin response to oral glucose tolerance test in patients with polycystic ovarian syndrome (PCOS) and matched controls was performed.