Showing papers in "Biomacromolecules in 2016"

TL;DR: Optically transparent wood with transmittance as high as 85% and haze of 71% was obtained using a delignified nanoporous wood template using refractive-index-matched prepolymerized methyl methacrylate (MMA).

TL;DR: It is shown that Ca(2+) ions in general facilitate chain aggregation and gelation, however, aggregation is predominantly affected by alginate monomer composition, which is found to correlate with chain stiffness under certain solution conditions.

TL;DR: In vitro and in vivo experiments suggest that these mussel-inspired, antifouling, antibacterial hydrogels have great potential for use in wound healing applications.

TL;DR: Halloysite clay is an aluminosilicate nanotube formed by rolling flat sheets of kaolinite clay used for loading, storage, and controlled release of active chemical agents, including anticorrosions, biocides, and drugs.

TL;DR: Using several phase contrast variations, the neutron wave vector (Q) dependence with the intensity showed that CNCs are in contact with the oil phase only via the surface of the CNC and not immersed in oil since the Porod behavior is observed over the whole Q-range revealing no deformation of the oil surface at a nanometer scale.

TL;DR: This Review summarizes the recent progress in rheological studies on CNF aqueous suspensions using rotational rheometry and discusses linear viscoelastic properties, i.e., frequency-dependent storage and loss moduli; shear flow behavior; local flow characteristics, etc.

TL;DR: Nanostructured SRHs with more structural similarity to natural ECM up-regulate cell-material interactions for faster tissue repair and more controlled stimuli-response to environmental changes.

TL;DR: The demonstrated acidic DES method exhibits certain advantages over previously reported CNC productions, namely, milder processing conditions and easily obtainable and relatively inexpensive biodegradable solvents with low toxicity.

TL;DR: In situ-gelling nanocomposite hydrogels based on poly(oligoethylene glycol methacrylate) and rigid rod-like cellulose nanocrystals (CNCs) that can overcome the challenge of weak mechanical properties and results in dramatic enhancements in mechanical properties coupled with faster gelation rates, decreased swelling ratios, and increased stability versus hydrolysis.

TL;DR: The high porosity of the scaffolds, high phosphate buffered saline (PBS) uptake, and cytocompatibility toward mesenchymal stem cells (MSCs) are confirmed and considered beneficial for use as a substitute for cartilage.

TL;DR: It is shown that unidirectional freezing of nanocellulose dispersions produces cellular foams with high alignment of the rod-like nanoparticles in the freezing direction, and the formed hydrogels were birefringent and displayed anisotropic laser diffraction patterns, suggesting preserved nano cellulose alignment and cellular structure.

TL;DR: The structural and mechanical characterizations of the silk films demonstrated the silk film prepared at RH 97% realized both crystallinity and ductility simultaneously, indicating the thermal stability, mechanical, and other properties of silk materials are regulated by their water content and crystallinity.

TL;DR: These discussions emphasize the importance of considering not only the catalytic system but also the monomer size and structure relations to thermodynamic equilibrium behavior, which offers an additional layer of complexity to the molecular toolbox.

TL;DR: A new, innovative cell-printing process, supplemented with a core-sheath nozzle and an aerosol cross-linking method, is suggested to obtain multilayered cell-laden mesh structure and a newly considered collagen-basedcell-laden bioink, which could lead to an efficient way to achieve 3D cell-lad mesh structures that mimic the anatomical architecture of a patient's defective region.

TL;DR: Utilization of these polymers provides significant benefits compared to heparin, including enhancing therapeutic efficacy and reducing side effects as a result of fine-tuning heparIn-binding motifs and other molecular characteristics.

TL;DR: A surface-initiated photoiniferter-mediated polymerization (SI-PIMP) strategy of constructing a "cleaning" zwitterionic outer layer on apolycationic bactericidal background layer to physically hinder the availability of polycationic moieties for mammalian cells in aqueous service shows great advantages in the infection-resistant applications.

TL;DR: The feasibility of using bioinspired HA-CA hydrogels as functional biomaterials for improved tissue regeneration in critical tissue defects is proved.

TL;DR: A hypoxia-responsive, diblock copolymer poly(lactic acid)-azobenzene-poly(ethylene glycol), which self-assembles to form polymersomes in an aqueous medium has potential for future applications in imaging and treatment of hypoxic tumors.

TL;DR: Direct evidence is provided for the antibacterial mechanism of polypeptide-based micelles and a strategy for synthesizing biodegradable antibacterial nanomaterials without antibiotic resistance is provided.

TL;DR: Results indicated that these biodegradable nanoparticles, as a class of effective pH-responsive and visible nanocarriers, have the potential to improve smart drug delivery and enhance the antitumor efficacy for biomedical applications.

TL;DR: A novel combination of M10P10 with HAMA forms an interesting class of hydrogels for cartilage bioprinting, which improved printability and resulted in three-dimensional constructs with excellent cell viability.

TL;DR: In this paper, a micellar supramolecular hydrogel was constructed using a low-molecular-weight methoxy poly(ethylene glycol) block polymer and α-cyclodextrin (α-CD) for topical ocular drug delivery.

TL;DR: Microencapsulated nanogels released from this platform were capable of inducing potent knockdown of secreted TNF-α levels in murine macrophages, further validating the potential for this approach to be used for the treatment of IBD.

TL;DR: The rheological properties and the penetration of differently sized carboxylated nanoparticles in pig pulmonary mucus, on different distance and time scales are investigated, suggesting the presence of smaller pores at the air-mucus interface compared to within mucus.

TL;DR: In this paper, the authors used Silk sericin (SS) to enhance fibroblast proliferation and improved wound healing process and improved extracellular matrix production, accelerating wound healing.

TL;DR: The reduction in Tg of PLA with improvement in elongation at break and multifold reduction in oxygen permeability offers this bionanocomposite films, a promising candidate for stringent food packaging applications.

TL;DR: Results unambiguously demonstrated that polyampholytes cryopreserve cells by strongly interacting with cell membrane, with hydrophobicity increasing the affinity for membrane interaction, which enables it to protect the membrane from various freezing-induced damages.

TL;DR: This work demonstrates that functional sustainable nanomaterials can be used for small scale oil-water separations, particularly for oil droplet transportation and harvesting of lipophilic compounds.

TL;DR: Flow cytometry and confocal laser scanning microscopy results demonstrated that HPAEG-AS1411 nanoparticles could be internalized into tumor cells via aptamer-mediated endocytosis and exhibited a high tumor cellular proliferation inhibition rate and low cytotoxicity to normal cells.

TL;DR: Collective in vivo data show that controlled release of FGF2 to the wounds by the coacervate significantly accelerates the wound healing by promoting cell proliferation, stimulating the secretion of vascular endothelial growth factor for re-epithelization, collagen deposition, and granulation tissue formation, and enhancing the expression of platelet endothelial cell adhesion molecule.