Showing papers in "Hormones and Behavior in 2019"

TL;DR: The evidence that EDCs affect developing hypothalamic neuroendocrine systems, and change behavioral outcomes in juvenile, adolescent, and adult life in exposed individuals, and even in their descendants is reviewed.

TL;DR: It is found that youth with greater insulin resistance had higher levels of anhedonia and more food seeking behaviors, reduced hippocampal and ACC volumes, and greater levels of ACC and hippocampal dysconnectivity to fronto‐limbic reward networks at rest.

TL;DR: The ability to efficiently generate targeted mutations in the prairie vole genome will greatly expand the utility of this model organism for discovering the genetic and circuit mechanisms underlying complex social behaviors, and serves as a proof of principle for expanding this approach to other non-traditional model organisms.

TL;DR: This is the first review of sex differences in cognitive deficits induced by sleep loss and how neuroendocrine mediators influence cognitive impairment induced by SD in both human and animal studies.

TL;DR: Results from p‐curve suggest that published studies have only 16% power to detect effects, while the own data show no robust interactions between testosterone and cortisol in predicting status‐striving personality features, and the implications for the Dual Hormone hypothesis are discussed.

TL;DR: The emergence of habitual same-sex sexual behavior may have been an important step in the evolution of cooperation outside of kinship and pair-bonds in one of the authors' closest phylogenetic relatives.

TL;DR: Examination of the effects of social isolation on vasopressin (AVP) V1a, oxytocin (OT) and serotonin (5-HT)1a receptor binding within the neural circuit controlling social behavior provides substantial new support for the proposition that the social environment can have a substantial impact on the structural and neurochemical mechanisms regulating social behavior.

TL;DR: Taurine prevents anxiety/fear‐like behaviors and protein carbonylation and dampens the cortisol response following acute stress in zebrafish, demonstrating a protective role of taurine against stress‐induced behavioral and biochemical changes.

TL;DR: What is currently known about prolactin and avian parental care is reviewed, a new hypothesis is proposed, and gaps in current understanding of prol actin's role in parental care are highlighted.

TL;DR: It is found that nanoparticle formulation increased BBB transport both in vitro and in vivo, and nanoparticle‐encapsulated oxytocin administered intranasally exhibited greater pro‐social effects both acutely and 3days after administration, in mouse social‐interaction experiments.

TL;DR: It is found that socially dominant males had significantly higher OTR binding in the nucleus accumbens core than subordinate animals and V1aRbinding in the rostral lateral septum and lateral preoptic area compared to subordinates.

TL;DR: The importance of the robust circadian dynamics of allostatic mediators, with a focus on the hypothalamic-pituitary-adrenal (HPA) axis, for the optimal regulation of host physiology and in enabling organisms to adequately respond and adapt to physiological stressors is highlighted.

TL;DR: Evidence is synthesized from different clinical populations including natural menopause, surgical menophere, women on chemotherapy, and preclinical stroke models to dissect the role of ovarian hormones and stroke risk and outcomes.

TL;DR: These data are the first to demonstrate cycle- and hormone-dependent effects on the motivational response to a food cue, and the only studies to date to determine how individual susceptibility to obesity influences NAc excitability, cue-triggered food-seeking, and differences in the regulation of these neurobehavioral responses by the estrous cycle.

TL;DR: The conclusion that mate relationships are rewarding for prairie voles is supported, despite selectivity of preferences for familiar individuals in partner preference tests, which suggests important differences in the pathways underlying these relationship types, even within species.

TL;DR: A better understanding of how changes in daytime light intensity impinge upon the neural substrates involved in affect and cognition will lead to novel preventive and therapeutic strategies for seasonal affective disorder, as well as for non-seasonal emotional or cognitive impairments associated with light deficiency.

TL;DR: The need for integration studies that combine multiple measures covering a broad range of social behaviors and link these to genetic and epigenetic profiles is advocated, as well as possible explanations how alterations affect the biological pathways underlying the aberrant social behavior.

TL;DR: The data suggest that DH-synthesized E2 and androgen receptor activation may work in concert to mediate memory consolidation in intact males, such that androgens receptor activation protects against memory impairments caused by aromatase inhibition.

TL;DR: For example, this paper found that mothers had significantly higher preferences for beards when judging fathering than all other women and mothers also judged beards as more masculine and older, but less attractive, than non-contractive and contraceptive users.

TL;DR: It is suggested that both compensatory maternal care and juvenile enrichment can reduce the impact of a low security environment, and how utilizing diverse models of resource (in)stability can reveal mechanisms that confer vulnerability and resilience to early life stress is highlighted.

TL;DR: This review addresses day-length dependent variation in physiology and behavior, and presents the current understanding of the mechanisms supporting selective social relationships in meadow voles, with connections to lessons from other species.

TL;DR: The results indicate androgen signaling is necessary for social ascent and hormonal signaling and social experience may shape the full suite of DOM‐typical behavioral patterns.

TL;DR: Downy woodpeckers are used as a model to evaluate how the machinery underlying androgen action can evolve to accommodate this bird's main territorial signal, the drum, and modifications to androgenic mechanisms in the primary neck muscle that actuates the hammering movements underlying this signal are evaluated.

TL;DR: Test for reproductive state-dependent plasticity in the eye of the cichlid fish Astatotilapia burtoni using behavioral, gene expression, neural activation, and electrophysiology techniques provide crucial evidence linking endocrine modulation of visual plasticity to mate choice behaviors in females.

TL;DR: The ability of Ago to alleviate behavioral symptoms and concomitant neuropathological events observed in a model of sporadic ADs suggests that this melatonin alternative can be considered a promising adjuvant in this disease.

TL;DR: State‐level anger intensity is associated with psychological and/or psychiatric vulnerability, but not exogenous testosterone therapy or serum testosterone levels in transgender people, even in presence of psychological/psychiatric vulnerability.

TL;DR: The Challenge Hypothesis is extended to potentially all endocrine systems, and not only control of secretion, but also transport mechanisms and how target cells are able to adjust their responsiveness to circulating levels of hormones independently of other tissues are explored.

TL;DR: The pubertal development of hypothalamic E2-facilitated progesterone synthesis appears to be one of the neural switches facilitating reproductive maturation, and this study hypothesized that a critical step in estrogen positive feedback was the ability for estradiol-induced neuroP synthesis.

TL;DR: The present study found that fathers initiated more paternal behavior and the virgin male showed more infanticide, and indicated that OT plays a key role in the modulation of paternal behavior via the medial preoptic area of the MPOA.

TL;DR: These findings provide important evidences that physical activity, exposure to EE, and the SP treatment during adolescent period can protect against adolescent stress induced behavioral, biochemical and neuroanatomical impairments in adulthood.