Showing papers in "Journal of Infection in 2010"

TL;DR: Procalcitonin (PCT) seems to be the most helpful laboratory marker for the differentiation of causes of fever, particularly in autoimmune, autoinflammatory and malignant diseases.

TL;DR: The most important finding is that higher mortality is associated with advanced age, being 13.5% in patients over 80 years and proposed minimum standards for reporting mortality in future studies.

TL;DR: CD64 expression on PMNs could be a useful diagnostic cell-based parameter of bacterial infections, however, published studies about this topic showed a low methodological quality.

TL;DR: Fusariosis, although uncommon, continues to have poor prognosis in neutropenic leukemic patients who present with fungemia, and was the only risk factor independently associated with 12-week mortality.

TL;DR: The wide range of causative organisms and degree of resistance to commonly used anti-microbials supports the importance of extensive intra-operative sampling and provides important information to guide clinicians' choice of empirical antibiotics.

TL;DR: The value of traditional and newer diagnostic tests is focused on and European networks are needed to define the best diagnostic and treatment strategies in order to reduce future challenge posed by PJIs.

TL;DR: MCFG was as effective as VRCZ and significantly safer than as an initial treatment of CPA and the safety of both drugs as initial treatment in Japan was significantly safer.

TL;DR: All returning travellers and migrants with eosinophilia should be investigated with concentrated stool microscopy and strongyloides serology, in addition to tests specific to the region they have visited, the British Infection Society guidelines group says.

TL;DR: Following surgery for treatment of PJI, antibiotic therapy appears able to be limited to a 6-week course, with one week of intravenous administration, with confirmation in randomized trials needed.

TL;DR: SCA screening has a substantial role for the early detection of cryptococcal infection in HIV-infected patients with low CD4 cell counts and routine screening with SCA should be performed in patients with CD4 < 100 cells/mm(3).

TL;DR: O Ongoing high-quality laboratory-based surveillance of IPD in all age groups is essential, and the impact of 7-valent pneumococcal conjugate vaccines, introduced in September 2006, provides a baseline for evaluating the impact.

TL;DR: The results demonstrate the variability of the virulence between strains, and suggest that bacterial proliferation is not the only virulence factor responsible for the pathogenesis in A. baumannii pneumonia.

TL;DR: The burden of sequelae due to pneumococcal meningitis remains high in the reviewed studies, as well as the influence of co-factors such as study design, study population and treatment on this risk.

TL;DR: The clinical features of the hospitalized pneumonia patients with 2009 H1N1 influenza in Taiwan were characterized and Clinicians could apply the three predictors at admission to identify the high-risk pneumonic patients for developing respiratory failure.

TL;DR: 2009 H1N1 Influenza caused mild symptoms in most patients with cancer and/or HSCT and may not be a substantial risk for poor outcome, however further studies are needed to validate the results.

TL;DR: CTX-M beta-lactamases may spread extensively amongst family members in the home, with both intra- and inter-household transmission.

TL;DR: The incubation period in this outbreak was significantly shorter than previously reported, a fact that may be due to the high number of ingested bacteria, as do treatment with antibiotics effective against L. monocytogenes in at-risk populations.

TL;DR: This study found vancomycin MIC creep among blood MRSA isolates over time, and clinical laboratories should adopt methods with the required precision to accurately determine MICs.

TL;DR: Public health bodies should consider the implementation of a mandatory vaccination policy for HCWs for future pandemics, in order to prevent nosocomial transmission and to protect patients at high-risk for influenza-related complications and death, and to assure the continuity of the essential health-care infrastructure.

TL;DR: Automated rep-PCR assays on the DiversiLab system were used for MRSA, A. baumannii and for the first time ESBL-producing Klebsiella spp.

TL;DR: The linear trend of increasing antimicrobial resistance among gram-negative isolates should be considered when empiric therapy is selected.

TL;DR: In this article, the distribution of virulence determinants and phylogenetic groups among community-onset, ciprofloxacin-resistant E. coli isolates causing urinary tract infections (UTIs) in Korea were investigated.

TL;DR: The data indicate that a low PCT value in a critically ill septic patient is more likely to be related to candidemia than to bacteremia, and this role in fungal infections is less defined than in patients with candidemia.

TL;DR: Enterococcal bacteremia was diagnosed in 1887 patients during the study period and was caused by non-faecalis and non-Faecium enterococci in 182 of these patients, showing that immunocompromised status is the only risk factor for the all cause mortality.

TL;DR: Treatment with piperacillin-tazobactam or ampicillin-sulbactam was associated with false-positive BAL GM results, and the BAL GM assay appears promising for the diagnosis of IPA.

TL;DR: The data suggests that this novel identified surface protein may be involved in leptospiral pathogenesis of Leptospira interrogans and Lyme borreliosis.

TL;DR: These findings confirm that mutations of gyrA codons 90, 91 and 94 constitute the primary mechanism of FQ resistance in MTB and indicate that the regional investigations are necessary for the comprehensive understanding of F Q resistance of MTB.

TL;DR: The proposed non-contact infection screening system appears promising for application in accurate screening for influenza patients at places of mass gathering.

TL;DR: An important, but probably underappreciated cross-reactivity with other Alphavirus like Chikungunya virus is present, which may become of clinical importance in the event the various Alphaviruses will have overlapping geographical distributions and in seroprevalence studies.

TL;DR: Bacteremia due to USA300 MRSA strains was associated with increased mortality, suggesting that USA300 strains may be more virulent.