Showing papers in "Journal of Orthopaedic Research in 2006"

TL;DR: The knee ligaments, particularly those of the posterior lateral corner, provided stability to the knee at certain periods of the stance phase, when activity of the important stabilizing muscles was low.

TL;DR: A wound healing response does occur at the healing rotator cuff insertion site, however, the characteristics of the tendon after healing differ significantly from the uninjured tendon insertion site at the longest time‐point studied.

TL;DR: The altered pre‐IC peroneus longus IEMG and increased inversion of the ankle joint observed in FI subjects could help to explain why subjects with FI may suffer from inversion injury to their ankle joint when subjected to an unanticipated ground contact.

TL;DR: The ranges of motion required to perform the activities studied are greater than that provided by most currently available joint prostheses, demonstrating the need for high range of motion implant design.

TL;DR: Delivery of chondrocytes in the form of cartilage tissue fragments in conjunction with appropriate polymeric scaffolds provides a novel intraoperative approach for cell‐based cartilage repair.

TL;DR: The ability of SIS‐ECM to recruit a population of marrow‐derived cells to the remodeling site may alter the default mechanism of tendon healing and explain in part the process of site specific constructive remodeling as opposed to scar tissue formation when the ECM is used as a biologic scaffold for tendon reconstruction.

TL;DR: The results of this study confirm that ESWT administered with the Dornier Epos Ultra is a safe and effective treatment for recalcitrant plantar fasciitis.

TL;DR: It is hypothesize that a beneficial biologic repair response can be induced by placing a collagen‐platelet rich plasma (collagen‐PRP) material into a central ACL defect.

TL;DR: As hip flexion had an impact on the nerves around the ankle and foot but not on the plantar fascia, the modified SLR may be a useful test to differentially diagnose plantar heel pain.

TL;DR: Significantly better performance of an osteoinduction ceramic in a critical‐sized orthotopic defect in a large animal model in comparison to a nonosteoinductive ceramic suggests osteoInduction to be clinically relevant.

TL;DR: This is believed to be the first set of patellar tracking data obtained in both flexion and extension motion while the patella was acted on by a full set of quadriceps muscle tensions acting in physiological directions.

TL;DR: A three‐dimensional finite element model of the human tibiofemoral joint was performed to examine the effect of lateral meniscectomy on knee biomechanics and found that under axial femoral compressive loads, the peak contact stress and maximum shear stress in the articular cartilage increased 200% more after a lateral than a medial menisicectomy.

TL;DR: This article showed that aggrecan is constitutively expressed by mesenchymal stem cells and that type X collagen is expressed as an early event, whereas the latter was expressed before type II collagen in some cases.

TL;DR: It is concluded that Poisson's ratio of articular cartilage is primarily controlled by the content and organization of the collagen network.

TL;DR: The relatively small differences in growth‐rate sensitivity to stress for a diverse set of growth plates suggest that these results might be generalized to other growth plates, including human, and may be applicable to planning the management of progressive deformities in patients having residual growth.

TL;DR: 6 degrees‐of‐freedom (DOF) in vivo kinematics of the human AJC is investigated using a combined dual‐orthogonal fluoroscopic and magnetic resonance imaging (MRI) technique to add quantitative data to an in vivo database of normals that can be used in clinical diagnosis, treatment, and evaluation of the AJC after injuries.

TL;DR: It is demonstrated that once S. aureus is established intracellularly for 12 h, the bacteria are less sensitive to antibiotics capable of eukaryotic cell penetration (statistically significant) and could be due in part to the observed structural changes.

TL;DR: This study corroborates the mechanoregulatory algorithms proposed to control tissue differentiation during bone healing with more extensive in vivo bone healing data from animal experiments to resolve the issue of which reflects the actual mechanobiological processes the best.

TL;DR: It is confirmed that controlled, noninvasive cyclic loading can improve the strength of healing callus, however, application of load immediately after fracture appears to be detrimental to healing.

TL;DR: Dexamethasone reduces both cell number and collagen synthesis in tenocyte cultures in a concentration‐dependent manner by both direct effects on tenocyte proliferation and collagen accumulation, and also by modulating the recruitment of tendon progenitor cells.

TL;DR: It can be concluded that disc degeneration generally results in a decrease of disc height and volume as well as a less convex disc shape in the absence of disc degenerations, however, age tends to result in an inverse relationship on disc height, volume, and shape.

TL;DR: The goal of this study was to determine the mechanical cause of early collagen damage in articular cartilage after mechanical overloading, and found that damage to the collagen network is an early event in cartilage degeneration.

TL;DR: It is demonstrated that the rabbitPBMSCs possessed multidifferentiation potential comparable with BMMSCs, and allogenic PBMSCs seeded onto porous calcium phosphate resorbable substitutes enhanced bone regeneration in the rabbit ulna critical‐sized bone defect model, suggesting allogenic MBMSCs may be a new source of circulating osteogenic stem cells for bone regeneration and tissue engineering.

TL;DR: The motions and moments in the hip and knee in female patients on the waiting list for knee prosthesis surgery with medial or lateral osteoarthritis were compared with a control group and an association between presence of lateral OA of the knee and the biomechanics of the hip joint was found.

TL;DR: Measurements of anteroposterior translation of the femoral component over the tibial base‐plate against joint flexion during daily living activities are essential for the assessment of the in vivo performance of current prosthesis designs.

TL;DR: The results of this investigation demonstrate that the adult environment is not an impediment to scarless repair and that this capability is intrinsic to the fetal tendon itself.

TL;DR: The current results demonstrate the feasibility of quantitative MRI, particularly T2 mapping, to reflect the mechanical properties of human patellar cartilage at both field strengths.

TL;DR: The results of this study indicate that the assembly load and the environment both play a role in the initial stability of modular hip taper connections.

TL;DR: It is hypothesized that cell surface integrins play a role in this mechanotransduction process, and as such respond to application of cyclic tensile load in ACL fibroblasts.

TL;DR: To identify gender differences in hip motion and kinetics during a single leg bidirectional deceleration maneuver, collegiate soccer players were instructed to start the maneuver balancing on one foot, to hop through an agility‐speed ladder on the same leg and then up one and hold it.