Showing papers in "Maturitas in 2018"

TL;DR: Studies using nanoparticles of other materials suggest that toxicity could potentially affect the central nervous system and the reproductive system, although this would be unlikely unless exposure levels were very high and absorption was increased by physiological factors.

TL;DR: Electronic healthcare technology is prevalent around the world and creates huge potential to improve clinical outcomes and transform care delivery, however, there are increasing concerns relating to the security of healthcare data and devices.

TL;DR: The results suggest that the differences in the composition of gut microbiota between genders and between women of different hormonal status may be related to the sexual dimorphism observed in the incidence of metabolic diseases and their co-morbidities.

TL;DR: The aggregated evidence supports the assertion that olive oil consumption is beneficial for human health, and particularly for the prevention of cardiovascular diseases, breast cancer, and type 2 diabetes mellitus.

TL;DR: An overview of the common challenges facing WT and an A-Z guide is presented, focusing on key terms, aiming to provide a grounded and broad understanding of current WT developments in healthcare.

TL;DR: An increased risk of incident dementia with hearing impairment is found in both the novel data and the meta-analysis, which is an important finding, particularly in light of recent suggestions that mid-life hearing loss may account for up to 9.1% of dementia cases worldwide.

TL;DR: Different types of interventions to reduce or prevent social isolation in later life, including one-to-one, group, service provision, technology-based, neighbourhood, and structural interventions are reviewed, highlighting the opportunities and the constraints associated with these different approaches.

TL;DR: In older, community-dwelling adults, consumer wearables accurately measure step count and activity duration, as confirmed by reference devices and validation methods Further research is required to understand how co-morbidities, gait and activity levels interact with monitoring in free-living environments.

TL;DR: This review summarizes study findings, where increased cortical activity appears to be required for older adults and further for participants with PD to perform walking and balance tasks, but specific activation patterns vary with the demands of the particular task.

TL;DR: BMI, childhood enuresis, and high-impact exercising were found to be the main associated risk factors for urinary incontinence in nulliparous adolescent and middle-aged women.

TL;DR: In women without a history of depression or anxiety, the perimenopause and postmenopausal stages are associated with increased risk of greater symptoms of anxiety and depression relative to premenopause.

TL;DR: Metabolic changes during the menopausal transition include an increase in and the central redistribution of adipose tissue, as well as a decrease in energy expenditure, which increases the risk of type 2 diabetes mellitus and MHT has a favourable effect on glucose metabolism.

TL;DR: VD deficiency in postmenopausal women was associated with a higher prevalence of MetS, hypertriglyceridemia and low HDL than those with adequate levels.

TL;DR: Circulating markers of oxidative stress are increased in sarc Openia and related to CVD risk in sarcopenic obesity, suggesting that redox balance analysis would be a useful part of a multidimensional evaluation in aging.

TL;DR: An adequate intake of calcium is recommended for general bone health and an increased risk for cardiovascular events, urolithiasis and even fractures has been found in association with excessive calcium intake, but this issue remains unresolved.

TL;DR: Clinicians should bear in mind that sexual dysfunctions have multifactorial causes and hypogonadism represents only one of these, and only hypog onadal men are likely to improve their sexual symptoms when treated with TTh.

TL;DR: It appears that protein does not elicit as great a satiating effect in older adults as it does in younger individuals, indicating that there is potential to increase protein intake without impacting on overall energy intake.

TL;DR: A narrative literature review encompassing the epidemiology of cold- and heat-related mortality and morbidity, related physiologic and environmental mechanisms, and municipal responses to hot and cold weather, illustrated by Detroit, Michigan, USA, a financially burdened city in an economically diverse metropolitan area.

TL;DR: Foot problems, particularly foot pain, hallux valgus and lesser toe deformity, are associated with falls in older people and Documentation of foot problems and referral to foot care specialists should be a routine component of falls risk assessment and prevention.

TL;DR: A cross-sectional study of a community-derived sample of adult volunteers suggests that hearing loss is a causative factor for clinically significant depression, anxiety and stress symptoms.

TL;DR: In this paper, a review of the impact of the human microbiome on drug metabolism, toxicity and efficacy is presented, focusing on the effect of those microbiomes or components thereof on the pharmacokinetics of specific chemotherapeutic agents, immunotherapy, anti-inflammatory and antimicrobial drugs.

TL;DR: A comprehensively review the literature and present updated information on targets for blood pressure (BP) and on the management of hypertension in patients with T2DM, as long as they are effective and safe and after taking co-morbidities into account.

TL;DR: PARO may have some effect on motor activity of older people with dementia in long-term care, but not on sleep patterns, as measured by a wearable triaxial accelerometer.

TL;DR: Gout is an increasingly common chronic disorder of urate crystal deposition that manifests as flares of acute inflammatory arthritis that is more common in men than women prior to menopause due to the uricosuric effects of oestrogen, but afterMenopause the incidence of gout rises substantially in women.

TL;DR: Multimorbidity is associated with poor HrQoL at mid-life at the population level, with some evidence of differences in association with age and disease cluster and sparse evidence on sex differences.

TL;DR: A more androgenic profile (higher free testosterone and lower SHBG levels) is associated with a greater increase in LVM in men and women and great increase in M:V ratio in women over the course of 9 years.

TL;DR: Frailty was a significant predictor of 3-year mortality in community-dwelling older adults, with the association being moderated by baseline cognitive status and the moderating effect of cognitive impairment.

TL;DR: Overall, this review found telehealth is an effective method to deliver malnutrition-related interventions to older adults living at home, and is likely to result in clinical improvements compared with usual care or no intervention, however, further research with larger samples and stronger study designs are required to strengthen the body of evidence.

TL;DR: Metabolic changes appear, overall, to be modest, confirming the safety of CSHT, and are partly in line with other studies concerning the impact ofCSHT on hormonal and metabolic parameters in transgender people.

TL;DR: The extent to which social exclusion experienced by adult informal carers of people living with dementia or severe mental health disorders has been identified and described in research literature was examined, synthesised qualitative and quantitative evidence and included the perspectives of carers themselves and of professionals.