Showing papers in "Natural Product Research in 2012"

TL;DR: The results revealed that basil oil has potent cytotoxicity and may belong to the methyl cinnamate and linalool chemotype.

TL;DR: The results show that bay laurel EO and its EX have potential as natural alternatives to synthetic food preservatives, in order to enhance food safety and increase food shelf life.

TL;DR: The total phenolic content and antioxidant activities of olive leaf extracts were determined and their antioxidant activities were evaluated using the diphenyl picrylhydrazyl method and the β-carotene linoleate model assay.

TL;DR: A comparative study of essential oil composition, polyphenol content and antioxidant activities of Lavandula coronopifolia, Lavandulas multifida and Lav andula stoechas subsp.

TL;DR: This study validated the traditional claim with pharmacological data that anti-inflammatory and antioxidant activity of F. carica leaves could be due to the presence of steroids and flavanoids, respectively, which are reported to be present in the drug.

TL;DR: Bulgaria propolis showed an important antibacterial action, as well as a synergistic effect with antibiotics acting on the ribosome, which points out a possible therapeutic strategy evaluating the use of propolis preparations for the treatment of Salmonella Typhi infection.

TL;DR: The results indicated that the extract of C. drabifolia subsp.

TL;DR: It is suggested that essential oil of C. limon and C. zeylanicum may suppress the growth of Acinetobacter species and could be a source of metabolites with antibacterial modifying activity.

TL;DR: Staphylococcus aureus strains were more susceptible to the tested plant products than E. coli, but all natural products promoted antimicrobial growth inhibition.

TL;DR: Analysis of wounds created in four groups of rat in posterior neck region revealed that the rate of wound healing was significantly accelerated in the wound dressed with A. paniculata extract compared to the blank placebo, and A.paniculata extracts significantly enhanced rate of wounds healing in rats.

TL;DR: The results show that cordymin is a potent anti-inflammatory and analgesic medicine.

TL;DR: The cytotoxic activity indicated a high proliferation inhibition for the birch tree extract but was still comparable with betulinic acid and betulin.

TL;DR: Essential oils from Colombian plants were characterised by GC–MS, and assayed for anti-quorum sensing activity in bacteria sensor strains, finding promising properties as QS modulators.

TL;DR: The ethanolic extract and fixed oil of the seeds exhibited anti-hyperlipedaemic and anti- hyperglycaemic activities and Oral administration of the fixed oil for 10 days resulted in a rise in serum calcium levels in rats.

TL;DR: Essential oil composition of the leaves of Viola odorata L. growing wild in Kashan, central Iran was extracted by hydro distillation–solvent extraction method and analysed using GC–MS technique and several components were identified for the first time in this chemotype of V. odorata.

TL;DR: In this study, lupeol, a phytoconstituent from Solanum xanthocarpum, is shown to suppress the progression of diabetes after 21 days and increased antioxidant levels, with a decrease in the level of thiobarbituric acid-reactive oxygen species.

TL;DR: It was found that the leaf extract had higher antioxidant potential than the flower extract and the antioxidant properties and total phenolic contents of the leaves were higher than those of the flowers.

TL;DR: To study its possible use as a natural herbicide, the essential oil of Cistus ladanifer was tested in vitro against Amaranthus hybridus, Portulaca oleracea, Chenopodium album, Conyza canadensis and Parietaria judaica, completely inhibiting A. hybridus germination, and nearly blocking C. Judaica germination at all concentrations assayed.

TL;DR: Three main naphthoquinones in the leaf extracts of Impatiens balsamina L. (Balsaminaceae) were evaluated by determination of minimal inhibitory concentrations (MICs) and minimal bactericidal or fungicidal concentrations (MBCs or MFCs) using a modified agar dilution method.

TL;DR: Water extract could be more pertinent to human nutrition as it contained a significant amount of catechin, which was comparable to traditional sources like green and black tea, and methanolic extract showed significant ferric reducing ability, moderate metal chelating activity and strong radical scavenging activity.

TL;DR: Eight phenanthrenes, 7-carboxy-2-hydroxy-1-methyl-5-vinyl-phenanthrene, effusol and juncusol, isolated from the aerial part of Juncus effusus showed anxiolytic and sedative activities.

TL;DR: Two fatty acids of Rhodobryum ontariense, 9,12,15-octadecatrien-6-ynoic and α-linolenic acid, have known cardio protective activity, which supports respective claims of traditional herbal use of these mosses.

TL;DR: The aqueous methanolic extracts of Melastoma malabathricum exhibited antib bacterial activity when assayed against seven microorganisms by the agar diffusion method, indicating the role of the free 3-OH for antibacterial activity.

TL;DR: β-sitosterol-β-D-glucoside (1) was found to reduce nitric oxide (NO) production from LPS-induced RAW 264.7 cells the most and may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO.

TL;DR: N-methylasimilobine, a new-found strong acetylcholinesterase (AChE) inhibitor, along with two weakly active aporphine alkaloids, nuciferine and nornuciferines, were separated from Nelumbo nukifera and molecular modelling was performed to explore the binding mode of inhibitor 1 at the active site of AChE.

TL;DR: The antioxidant effects of RA in vitro might be generally considered to be a result of the presence of phenolic compounds (including flavonoids) but not astragalosides and polysaccharides.

TL;DR: Lantana ukambensis and Acacia macrostachya induced a very significant antiproliferative effect against cancer cells and developed a strong antioxidant activity and are therefore potential sources for isolating new antioxidant and anticancer molecules.

TL;DR: In this article, the in-vitro cytotoxicity of the crude alkaloidal fraction (CAF) against the cell lines HeLa, Hep-G2, HEP-2 and HCT116, MCF-7 and HFB4 showed promising activity, with IC50 values of 13.8, 10.1, 8.16, 13.9, 11.4 and 12.2

TL;DR: The unique structure of xanthones, including the catecholic moiety and the completely conjugated system, enables them to be promising antioxidants and good correlation was observed between TPC and DPPH scavenging activity among the extracts.

TL;DR: The inhibitory potential showed by turmerin against enzymes linked to type 2 diabetes, as well as its moderate AO capacity, could rationalise the traditional usage of turmeric rhizome preparations against diabetes.