Showing papers in "Value in Health in 2009"

TL;DR: The aim of this article is to review the concept of the qualityadjusted life-year (QALY), a widely used measure of health improvement that is used to guide health-care resource allocation decisions and address variations on the conventional QALY.

TL;DR: The theoretical, simulation results and real data example demonstrate that the use of the stabilized weights in the pseudo data preserves the sample size of the original data, produces appropriate estimation of the variance of main effect, and maintains an appropriate type I error rate.

TL;DR: This report of an ISPOR Good Practices Task Force reviews what national guidelines for economic evaluation say about transferability, discusses which elements of data could potentially vary from place to place, and recommends good research practices for dealing with aspects of transferability.

TL;DR: Recommendations regarding the study designs and statistical approaches for assessing measurement equivalence are provided and provide a general framework for decisions regarding the level of evidence needed to support modifications that are made to PRO measures when they are migrated from paper to ePRO devices.

TL;DR: This study establishes the South Korean population-based preference weights for EQ-5D based on values elicited from a representative national sample using the time trade-off (TTO) method and the value set derived here is based on a representative population sample, limiting the interpolation space and possessing better model performance.

TL;DR: Comparative effectiveness research in the form of nonrandomized studies using secondary databases can be designed with rigorous elements and conducted with sophisticated statistical methods to improve causal inference of treatment effects.

TL;DR: The results of an ISPOR task force convened to address good clinical research practices for the use of existing or modified PRO instruments to support medical product labeling claims are presented.

TL;DR: The Adherence to Refills and Medications scale is a valid and reliable medication adherence scale when used in a chronic disease population, with good performance characteristics even among low-literacy patients.

TL;DR: The inherent biases when using secondary data sources for comparative effectiveness analysis are discussed and methodological recommendations are provided to help mitigate these biases.

TL;DR: Valid findings of causal therapeutic benefits can be produced from nonrandomized studies using an array of state-of-the-art analytic techniques.

TL;DR: This report and the decision tools proposed will assist those involved with multinational trials to decide on the translations required for each country and choose the approach to use when the same language is spoken in more than one country.

TL;DR: It is argued that the economic evaluation of devices raises additional challenges that international guidelines frequently overlook.

TL;DR: The spread suggests that coverage decisions using dialysis as the benchmark may need to incorporate percentile values higher than the average to be consistent with the Rawlsian principles of justice of preserving the rights and interests of society's most vulnerable patient groups.

TL;DR: Four issues are addressed in possible valuation perspectives of ex ante health state utilities, including the exist-ence of unwillingness to trade lifetime in elicitations of experi-enced utility, and the discrepancy between aggregateindividual utility of health programs on the one hand and societal valuations that include concerns for fairness.

TL;DR: The significant relationship between clinical and quality of life data provides support for the use of CMCs to increase interpretability of FACT-P scores.

TL;DR: Only parameterizing the uncertainty directly in the model can inform the decision to conduct further research to resolve this source of uncertainty, and the value of research was particularly sensitive to these uncertainties and the methods used to characterize it.

TL;DR: Differences in methods may obscure true differences in values between countries, but population-specific valuation sets for countries engaging in economic evaluation would better reflect cultural differences and are therefore more likely to accurately represent societal attitudes.

TL;DR: FTAP is an effective and cost-saving measure for mitigating pandemic influenza and in combination with school closure as well as prevaccination is the most effective single strategy.

TL;DR: The influential role of cost-utility analysis (CUA) as part of an information toolkit for high-level decisionmaking is unlikely to be radically altered in the next 5 to 10 years.

TL;DR: This study reviews the current understanding of the burden of migraine in the U.S., the history of economic understanding of migraine treatment and identifies emergent trends for future studies evaluating clinical and economic outcomes of migraines.

TL;DR: Earlier versions of the other articles in this Value in Health Special Issue, Moving the QALY Forward: Building a Pragmatic Road (articles 2–6) were presented at an ISPOR Development Workshop held in Philadelphia from November 6–8, 2007.

TL;DR: There is potential to estimate EQ-5D values using responses to the disease-specific EORTC QLQ C-30 measure of quality of life, which implies that in studies that do not include disease- specific measures, it might still be possible to estimate QALYs.

TL;DR: Important variation among cost estimates was evident, even within studies of the same population, and readers should be cautious when comparing estimated coefficients from various studies because methodological issues might explain differences in the results of costs of nonadherence in diabetes.

TL;DR: Women with HSDD showed more HRQOL impairment than healthy population norms but were similar to adults with other chronic conditions such as diabetes and back pain.

TL;DR: MPR and PDC were among the best predictors of any-cause and mental health-related hospitalization, and are recommended as the preferred adherence measures when a single measure is sought for use with administrative claims data for patients not on polypharmacy.

TL;DR: This study provides an Argentine value set that could be used locally or regionally, with meaningful and significant differences with that of the United States.

TL;DR: The SF-8 instrument performs well among those with poor QOL across the continuum of the latent trait and thus can recognize more effectively persons with relatively poorer QOL than those with relatively better QOL.

TL;DR: Evidence on the ability of QLQ-C30 scale scores to validly predict 15D and SF-6D utilities, and to a lesser extent, EQ-5D, has been provided.

TL;DR: Attribute framing can influence willingness to pay and benefit: harm trade-offs from DCEs and Appropriate design and analysis methods should be explored to further characterize the influence and extent of framing in discrete choice studies.

TL;DR: In this article, the authors present a relatively novel method for modeling length-of-stay data and assess the role of covariates, some of which are related to adverse events.