Showing papers in "World Allergy Organization Journal in 2011"

TL;DR: The illustrated World Allergy Organization (WAO) Anaphylaxis guidelines focus on the supreme importance of making a prompt clinical diagnosis and on the basic initial treatment that is urgently needed and should be possible even in a low resource environment.

TL;DR: The current knowledge is summarized and the current and future strategies for the modulation of oxidative stress in asthma are discussed.

TL;DR: Promising research suggests that the interleukin-13 pathway may be an important target in the treatment of the different asthma phenotypes.

TL;DR: All H1-antihistamines have anti-inflammatory effects but it requires regular daily dosing rather than dosing 'on-demand' for this effect to be clinically demonstrable.

TL;DR: The ongoing identification of immune effector cells and mediators involved in the allergic cascade indicates that further research is necessary to define the role of antihistamines such as desloratadine in anti-inflammatory therapy.

TL;DR: Results of this survey form a useful framework for developing educational and training needs and for improving access to drug allergy diagnostic and treatment modalities across WAO member societies.

TL;DR: An update on climate change, migration, and allergy is provided and discusses factors for consideration when making recommendations for local allergy service provision, and for assessing an individual patient's environmental exposures.

TL;DR: Routine long-term prophylaxis with either attenuated androgens or C1-esterase inhibitor has been shown to reduce the frequency and severity of HAE attacks.

TL;DR: During the years 1972–1990 I was studying the mechanism of activation of the plasma bradykinin cascade, and it was resolved that there is a high molecular weight kininogen (HK) that is rather selectively cleaved by plasma kallikrein to yield bradykinsin, whereas low molecular weight Kininogen is preferentially Cleaved by tissue kallkalliklein to produce lysylbradykinIn (kallidin).

TL;DR: Not every wheeze is indicative of asthma but prediction of asthma in persistent wheezers is possible and testing for allergy in these infants is worthwhile and can be of significant value in avoidable allergens.

TL;DR: Allergenic composition of the nematode Ascaris lumbricoides and their potential impact on allergy sensitization and asthma pathogenesis and prevalence in populations living in the tropics and naturally exposed to both, mite allergens and helminth infections are discussed.

TL;DR: Profiling circulating miRNA might provide the highest specificity and sensitivity to diagnose asthma; similarly, correcting potential defects in the miRNA regulation network may lead to new therapeutic modalities to treat this disease.

TL;DR: There is an urgent requirement for the implementation of better ways to treat asthma in underserved populations, enhancing the access to preventive medications and educational approaches with modern technological methods.

TL;DR: It is speculated that the effect of intranasal steroids on eye symptoms in allergic rhinitis was related to their inhibition of the nasal-ocular reflex and data previously generated from the laboratory is presented to support this assumption in a nasal challenge model.

TL;DR: A randomly sampled, cross-sectional serology test-based survey was conducted in Lebanon to describe the pattern of food allergy among Lebanese population, and specific IgE to peanut in infants, children, and adults were higher than for sesame, peanut-induced allergic reactions were mild.

TL;DR: smoking prevention and standardized management programs for asthma and COPD are now available but prompt actions are needed to make them more effective in this region and thus avoid an adverse impact on national economic development.

TL;DR: Nasal glucocorticosteroids (NGCS) are helpful in reducing the amount of rebound congestion in patients with perennial allergic rhinitis with RM and may offer a protective benefit from the development of RM.

TL;DR: These observations if corroborated by in vivo data may possibly account for the deleterious effect of long-term therapy with β2-bronchodilators and inhaled glucocorticosteroids on the natural history of asthma.

TL;DR: The increasing knowledge of the mechanisms of immunotherapy has informed both novel approaches and the development of putative biomarkers that might predict the clinical response to immunotherapy, which has resulted from parallel studies performed in the United States.

TL;DR: High aeroallergen sensitization prevalence is found in a pediatric population with recurrent episodes of wheezing examined in the Allergy and Immunology Division of the Eva Perón School Hospital, which is in the southern area of the province of Santa Fe in Argentina.

TL;DR: The FFQ will reliably divide the population into groups with markedly different peanut consumption levels, especially at low levels of peanut consumption, as it was validated against the gold standard, the 7DFDR.

TL;DR: In conclusion, levocetirizine resulted to improve the quality of life and the symptoms related to AR and also to reduce the overall costs of the disease after 6 months treatment.

TL;DR: Allergic and inflammatory responses were induced by both grass pollen grains and their isolated washed and unwashed PCGs, however, on the basis of humoral and cellular responses, differential patterns were observed.

TL;DR: Dloratadine is effective in the treatment of AR in Arab and Asian subjects in the Middle East Gulf region and PNIF measures of nasal congestion were significantly improved after treatment.

TL;DR: It is demonstrated that the drug with better ability to suppress the histamine skin effects in experiments in healthy volunteers (levocetirizine) is also superior in improving the different aspects of control of chronic urticaria (subjective and objective symptoms, quality of life) and that increasing its dose of up to fourfold improves significantly the chances of successful treatment.

TL;DR: Increasing the awareness for allergic symptoms is the key not only for the diagnosis but also for the optimal treatment, therefore, education is an important component of prevention and control of allergic diseases.

TL;DR: Chemical modification is a practical and highly effective approach for achieving hypoallergenicity of recombinant allergens with retained immunogenicity.

TL;DR: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and IgE immunoblotting showed all 13 grasses share a high degree of homology, particularly in terms of group 1 and 5 allergens.

TL;DR: The History of the World Allergy Organization traces the global arc of the allergy field over the past 60 years and invites prominent leaders who are interested in being part of this history project to write about their time with IAACI-WAO.

TL;DR: The GA2LEN 1-day training programs on selected allergic diseases are an effective means to improve levels of knowledge on these diseases in physicians including general practitioners and the use of these training programs should be promoted and increased.