Journal ArticleDOI
A biodegradable "Nano-donut" for magnetic resonance imaging and enhanced chemo/photothermal/chemodynamic therapy through responsive catalysis in tumor microenvironment.
Guan Shaoqi,Xijian Liu,Yang Fu,Chunlin Li,Jinxia Wang,Qixiang Mei,Guoying Deng,Wenrui Zheng,Zhiping Wan,Jie Lu +9 more
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TLDR
In this paper, a biodegradable "Nano-donut" (CMPB-MoS2-PEG) is fabricated for magnetic resonance (MR) imaging and enhanced photothermal therapy (PTT)/ chemodynamic therapy (CDT)/chemotherapy through responsive catalysis in tumor microenvironment (TME).About:
This article is published in Journal of Colloid and Interface Science.The article was published on 2022-02-15. It has received 42 citations till now. The article focuses on the topics: Photothermal therapy & Doxorubicin.read more
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Intracellular Mutual Amplification of Oxidative Stress and Inhibition Multidrug Resistance for Enhanced Sonodynamic/Chemodynamic/Chemo Therapy.
Shaoqi Guan,Xijian Liu,Chunlin Li,Xingyan Wang,Dongmiao Cao,Jinxia Wang,Lizhou Lin,Jie Lu,Guoying Deng,Junqing Hu +9 more
TL;DR: The as-prepared intelligent biodegradable mZMD provides an innovative strategy to enhance SDT/CDT/chemotherapy through promoting oxidative stress and overcoming the multidrug resistance.
Journal ArticleDOI
Copper-doped MOF-Based Nanocomposite for GSH Depleted Chemo/Photothermal/Chemodynamic Combination Therapy
TL;DR: In this paper , a copper-doped ZIF-8-based nanocomposite for cancer combination therapy was constructed, which could deplete over 50% of intracellular glutathione (GSH) to disturb redox homeostasis.
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Multifunctional phototheranostic nanoplatform based on polydopamine-manganese dioxide-IR780 iodide for effective magnetic resonance imaging-guided synergistic photodynamic/photothermal therapy
TL;DR: In this paper , the authors demonstrated the design and development of a multifunctional nanoplatform (PMIDA), referring to polydopamine (PDA)-manganese dioxide (MnO2)-IR780, for imaging-guided phototherapy.
Journal ArticleDOI
Manganese-based hollow nanoplatforms for MR imaging-guided cancer therapies
TL;DR: In this paper , a review summarizes various hollow manganese (Mn)-based nanoplatforms, including hollow MnxOy, hollow matrix-supported MnXOy and hollow Mn-doped nanoparticles.
Journal ArticleDOI
Mutual Promotion of Oxidative Stress Amplification and Calcium Overload by Degradable Spatially Selective Self-Cascade Catalyst for Synergistic Tumor Therapy
Qiang Wang,Chunlin Li,Hansong Jin,Xingyan Wang,Cheng Ding,Dongmiao Cao,Linjing Zhao,Guoying Deng,Jie Lu,Zhiping Wan,Xijian Liu +10 more
TL;DR: In this paper , a degradable space-selective multifunctional nanocatalyst-CMFO reached self-cascade catalysis to mutually promote oxidative stress amplification and calcium overload for synergistic tumor therapy with MRI guide.
References
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Journal ArticleDOI
Chemodynamic Therapy: Tumour Microenvironment‑Mediated Fenton and Fenton‑like Reactions
TL;DR: Various strategies based on the Fenton reaction have been employed to enhance hydroxyl radical generation, including nanomaterials selection, modulation of the reaction environment, and external energy fields stimulation, which are discussed systematically in this Minireview.
Journal ArticleDOI
Copper selenide nanocrystals for photothermal therapy.
Colin M. Hessel,Varun P. Pattani,Michael R. Rasch,Matthew G. Panthani,Bonil Koo,James W. Tunnell,Brian A. Korgel +6 more
TL;DR: In vitro photothermal heating of Cu(2-x)Se nanocrystals in the presence of human colorectal cancer cell (HCT-116) led to cell destruction after 5 min of laser irradiation at 33 W/cm(2), demonstrating the viabilitiy of Cu
Journal ArticleDOI
Self-Assembled Copper-Amino Acid Nanoparticles for in Situ Glutathione "AND" H2O2 Sequentially Triggered Chemodynamic Therapy.
Baojin Ma,Shu Wang,Feng Liu,Shan Zhang,Jiazhi Duan,Zhao Li,Ying Kong,Yuanhua Sang,Hong Liu,Hong Liu,Wenbo Bu,Wenbo Bu,Linlin Li +12 more
TL;DR: Self-assembled copper-amino acid mercaptide nanoparticles (Cu-Cys NPs) for in situ glutathione-activated and H2O2-reinforced chemodynamic therapy for drug-resistant breast cancer efficiently inhibited drug- resistant breast cancer without causing obvious systemic toxicity.
Journal ArticleDOI
A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy.
Min Zhou,Rui Zhang,Miao Huang,Wei Lu,Shaoli Song,Shaoli Song,Marites P. Melancon,Mei Tian,Dong Liang,Chun Li +9 more
TL;DR: The combination of small diameter, strong NIR absorption, and integration of (64)Cu as a structural component makes these CuS NPs ideally suited for multifunctional molecular imaging and therapy.
Journal ArticleDOI
Plasmonic Copper Sulfide Nanocrystals Exhibiting Near-Infrared Photothermal and Photodynamic Therapeutic Effects
Shunhao Wang,Andreas Riedinger,Andreas Riedinger,Hongbo Li,Changhui Fu,Huiyu Liu,Linlin Li,Tianlong Liu,Longfei Tan,Markus J. Barthel,Giammarino Pugliese,Francesco De Donato,Marco Scotto d'Abbusco,Xianwei Meng,Liberato Manna,Huan Meng,Teresa Pellegrino +16 more
TL;DR: Interestingly, it is observed that, besides a high PTT efficacy, these copper sulfide NCs additionally possess intrinsic NIR induced photodynamic activity, whereupon they generate high levels of reactive oxygen species.