A novel strategy to enhance interfacial adhesion in fiber-reinforced calcium phosphate cement
TLDR
The aim of the present work was to improve the interfacial adhesion between fibers and matrix to obtain tougher biocompatible fiber-reinforced calcium phosphate cements (FRCPCs), which resulted in an increase of the work of fracture (several hundred-fold increase), while the elastic modulus and bending strength were maintained similar to the materials without additives.Abstract:
Calcium phosphate cements (CPCs) are extensively used as synthetic bone grafts, but their poor toughness limits their use to non-load-bearing applications. Reinforcement through introduction of fibers and yarns has been evaluated in various studies but always resulted in a decrease in elastic modulus or bending strength when compared to the CPC matrix. The aim of the present work was to improve the interfacial adhesion between fibers and matrix to obtain tougher biocompatible fiber-reinforced calcium phosphate cements (FRCPCs). This was done by adding a polymer solution to the matrix, with chemical affinity to the reinforcing chitosan fibers, namely trimethyl chitosan (TMC). The improved wettability and chemical affinity of the chitosan fibers with the TMC in the liquid phase led to an enhancement of the interfacial adhesion. This resulted in an increase of the work of fracture (several hundred-fold increase), while the elastic modulus and bending strength were maintained similar to the materials without additives. Additionally the TMC-modified CPCs showed suitable biocompatibility with an osteoblastic cell line.read more
Citations
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References
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Journal ArticleDOI
Fibre-reinforced calcium phosphate cements: a review.
Cristina Canal,Maria-Pau Ginebra +1 more
TL;DR: The present work aims at providing an overview of the different approaches taken and identifying the most significant achievements in the field of fibre-reinforced calcium phosphate cements for clinical applications, with special focus on their mechanical properties.
Journal ArticleDOI
Fiber reinforced calcium phosphate cements -- on the way to degradable load bearing bone substitutes?
Reinhard Krüger,Jürgen Groll +1 more
TL;DR: Future research will have to focus on the selection and tailoring of FRCPC components, fiber-matrix compatibilization, integral composite design and the adjusted degradation behavior of the composite components to ensure successful long term behavior and make the composites strong enough for application in load bearing defects.
Journal ArticleDOI
Reinforcement of a self-setting calcium phosphate cement with different fibers.
TL;DR: Fiber length, fiber volume fraction, and fiber strength were found to be key microstructural parameters that controlled the mechanical properties of CPC composites.
Journal ArticleDOI
Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug.
TL;DR: The strengthening of the structure was related to the reduction of porosity and the lower size of the precipitated crystals, as observed by scanning electron microscopy.
Journal ArticleDOI
Calcium phosphate-based ceramic and composite materials for medicine
TL;DR: The topical problems in chemistry and technology of materials based on calcium phosphates aimed at both the replacement of damaged bone tissue and its regeneration are discussed in this paper, where specific features of the synthesis of nanocrystalline powders and the fabrication of ceramic implants are described.
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