Journal ArticleDOI
A polydimethylsiloxane (PDMS) deformable diffraction grating for monitoring of local pressure in microfluidic devices
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TLDR
In this article, a deformable diffraction grating is used for measuring local pressure in microfluidic devices using a deformation grating, which consists of 5µm wide, 2 µm deep rectangular grooves arrayed with a period of 10 µm.Abstract:
In this paper, a novel optical method for monitoring of local pressure in microfluidic devices using a deformable diffraction grating is presented. A test device was fabricated with transparent silicone elastomer - polydimethylsiloxane (PDMS) - using the replica moulding technique. The moulded PDMS chip and a flat glass plate have a bonding interface, which defines a 2 mm×2 mm diffraction grating and a 200 µm wide, 20 µm deep microchannel. The grating consists of 5 µm wide, 2 µm deep rectangular grooves arrayed with a period of 10 µm. All the grooves are connected to the microchannel, and deformed by internal pressure. The optical response of the device to pressure ranging from -80 to 100 kPa is presented and compared with the theoretical prediction. It is also demonstrated that the test device can be used for measurement of air flow rates ranging from 0 to 0.3 ml min-1. The major advantages of this method are simple design and inexpensive fabrication. This method is not only desirable for flow characterization of microfluidic devices, but also opens up the possibility of producing new types of fibre-optic pressure sensor and pressure-driven optical modulator.read more
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References
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Journal ArticleDOI
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
Journal ArticleDOI
Three-dimensional micro-channel fabrication in polydimethylsiloxane (PDMS) elastomer
TL;DR: In this article, a fabrication technique for building 3D micro-channels in polydimethylsiloxane (PDMS) elastomer is described, which allows for the stacking of many thin (less than 100-/spl mu/m) patterned PDMS layers to realize complex 3D channel paths.
Journal ArticleDOI
The mechanical properties of the rubber elastic polymer polydimethylsiloxane for sensor applications
TL;DR: Polydimethylsiloxane (PDMS) is a commercially available physically and chemically stable silicone rubber as mentioned in this paper, which has a unique flexibility with a shear elastic modulus due to one of the lowest glass transition temperatures of any polymer.
Journal ArticleDOI
Patterned Delivery of Immunoglobulins to Surfaces Using Microfluidic Networks
Emmanuel Delamarche,André Bernard,André Bernard,Heinz Schmid,Heinz Schmid,Bruno Michel,Bruno Michel,Hans Biebuyck,Hans Biebuyck +8 more
TL;DR: The microfluidic networks used to pattern biomolecules with high resolution on a variety of substrates suggest a practical way to incorporate biological material on technological substrates.