Journal ArticleDOI
Micro total analysis systems. 2. Analytical standard operations and applications.
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This second part of the review of microfluidic system preparation will cover a number of standard operations as well as some biological applications of micro total analysis systems.Abstract:
After having reviewed some aspects of microfluidic system preparation in the first part (1), in this second part of the review we will cover a number of standard operations (namely: sample preparation, sample injection, sample manipulation, reaction, separation, and detection) as well as some biological applications of micro total analysis systems (namely: cell culture, polymerase chain reaction, DNA separation, DNA sequencing, and clinical diagnostics). As previously, we will include papers issued from different scientific journals as well as useful abstracts from three conference proceedings: MEMS, Transducers, and μTAS. In this second part, we do not include the period covered by the history section (1975-1997) from part 1 but try to cover the relevant examples of the literature published between January 1998 and March 2002. We briefly describe articles that struck us as needing special attention, while more “standard” papers are dutifully reported in groups of interest. An article might be included in more than one section, depending on the ideas developed in it.read more
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Journal ArticleDOI
Microfluidics: Fluid physics at the nanoliter scale
Todd M. Squires,Stephen R. Quake +1 more
TL;DR: A review of the physics of small volumes (nanoliters) of fluids is presented, as parametrized by a series of dimensionless numbers expressing the relative importance of various physical phenomena as mentioned in this paper.
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Engineering flows in small devices
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Femtosecond laser micromachining in transparent materials
Rafael R. Gattass,Eric Mazur +1 more
TL;DR: In this article, the physical mechanisms and the main experimental parameters involved in femtosecond laser micromachining of transparent materials, and important emerging applications of the technology are described.
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A review of micropumps
Daniel J. Laser,Juan G. Santiago +1 more
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Micromixers?a review
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TL;DR: In this paper, the authors report the progress on the recent development of micromixers and present different types and designs of active and passive MCMs, as well as the operation points of the MCMs.
References
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Journal ArticleDOI
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
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Chaotic Mixer for Microchannels
Abraham D. Stroock,Stephan K. W. Dertinger,Armand Ajdari,Igor Mezic,Howard A. Stone,George M. Whitesides +5 more
TL;DR: This work presents a passive method for mixing streams of steady pressure-driven flows in microchannels at low Reynolds number, and uses bas-relief structures on the floor of the channel that are easily fabricated with commonly used methods of planar lithography.
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Micro Total Analysis Systems. 1. Introduction, Theory, and Technology
TL;DR: In this article, the authors present a review of the book.http://www.reviewreviews.com/reviews/book-reviews-of-the-book
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A Group-IV Ferromagnetic Semiconductor: MnxGe1−x
Yun Daniel Park,Aubrey T. Hanbicki,Steven C. Erwin,C. S. Hellberg,James M. Sullivan,J. E. Mattson,T. Ambrose,A. Wilson,George Spanos,Berend T. Jonker +9 more
TL;DR: Calculated spin interactions and percolation theory predict transition temperatures larger than measured, consistent with the observed suppression of magnetically active Mn atoms and hole concentration.
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Functional integration of PCR amplification and capillary electrophoresis in a microfabricated DNA analysis device.
Adam T. Woolley,Dean R. Hadley,Phoebe Landre,Andrew J. deMello,Richard A. Mathies,Northrup Ma +5 more
TL;DR: The feasibility of performing high-speed DNA analyses in microfabricated integrated fluidic systems is established, demonstrating that challenging amplifications of diagnostically interesting targets can also be performed.