ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: Executive summary and recommendations: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on the management of patients with unstable angina)
Eugene Braunwald,Elliott M. Antman,John W. Beasley,Robert M. Califf,Melvin D. Cheitlin,Judith S. Hochman,Robert H. Jones,Dean J. Kereiakes,Joel Kupersmith,Thomas N. Levin,Carl J. Pepine,John W. Schaeffer,Earl E. Smith,David E Steward,Pierre Theroux,Raymond J. Gibbons,Joseph S. Alpert,David P. Faxon,Valentin Fuster,Gabriel Gregoratos,Loren F. Hiratzka,Alice K. Jacobs,Sidney C. Smith +22 more
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The present guidelines supersede the 1994 guidelines and summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy.Abstract:
The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Practice Guidelines was formed to make recommendations regarding the diagnosis and treatment of patients with known or suspected cardiovascular disease. Coronary artery disease (CAD) is the leading cause of death in the United States. Unstable angina (UA) and the closely related condition non–ST-segment elevation myocardial infarction (NSTEMI) are very common manifestations of this disease. These life-threatening disorders are a major cause of emergency medical care and hospitalizations in the United States. In 1996, the National Center for Health Statistics reported 1 433 000 hospitalizations for UA or NSTEMI. In recognition of the importance of the management of this common entity and of the rapid advances in the management of this condition, the need to revise guidelines published by the Agency for Health Care Policy and Research (AHCPR) and the National Heart, Lung and Blood Institute in 1994 was evident. This Task Force therefore formed the current committee to develop guidelines for the management of UA and NSTEMI. The present guidelines supersede the 1994 guidelines.
The customary ACC/AHA classifications I, II, and III summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy:
Class I: Conditions for which there is evidence and/or general agreement that a given procedure or treatment is useful and effective .
Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
Class IIa: Weight of evidence/opinion is in favor of usefulness/efficacy.
Class IIb: Usefulness/efficacy is less well established by evidence/opinion.
Class III: Conditions for which there is evidence and/or general agreement that the procedure/treatment is not useful/effective and in some cases may be harmful.
The weight of the evidence was ranked highest (A) if the data …read more
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Essential Features of a Surveillance System to Support the Prevention and Management of Heart Disease and Stroke A Scientific Statement From the American Heart Association Councils on Epidemiology and Prevention, Stroke, and Cardiovascular Nursing and the Interdisciplinary Working Groups on Quality of Care and Outcomes Research and Atherosclerotic Peripheral Vascular Disease
David C. Goff,Lawrence F. Brass,Lynne T. Braun,Janet B. Croft,Judd D. Flesch,F.G.R. Fowkes,Yuling Hong,Virginia J. Howard,Sara L. Huston,Stephen F. Jencks,Russell V. Luepker,Teri A. Manolio,Christopher J. O'Donnell,Rose Marie Robertson,Wayne D. Rosamond,John S. Rumsfeld,Stephen Sidney,Zhi Jie Zheng +17 more
TL;DR: In this paper, a review of the existing surveillance system for monitoring progress toward preventing heart disease and stroke in the United States and recommendations for filling important gaps in that system are provided.
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Moderate alcohol consumption induces sustained cardiac protection by activating PKC-ε and Akt
TL;DR: C57BL/6 mice were fed 18% ethanol (vol/vol) in drinking water for 12 wk and Isovolumic hearts were subjected to 20 min of ischemia and 30 min of reperfusion on a Langendorff apparatus.
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Circulating Endothelial Cell Count as a Diagnostic Marker for Non–ST-Elevation Acute Coronary Syndromes
Jacques Quilici,Nathalie Banzet,Philippe Paule,Jean-Baptiste Meynard,Murielle Mutin,Jean-Louis Bonnet,Pierre Ambrosi,José Sampol,Françoise Dignat-George +8 more
TL;DR: CEC count can be used as an early, specific, independent diagnostic marker for non–ST-elevation ACS and a combined strategy using CEC count and troponin I level could provide an effective diagnostic tool.
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Cardiovascular disease in the Eastern Mediterranean region: epidemiology and risk factor burden.
Karam Turk-Adawi,Nizal Sarrafzadegan,Ibtihal Fadhil,Kathryn A. Taubert,Masoumeh Sadeghi,Nanette K. Wenger,Nigel S Tan,Sherry L. Grace,Sherry L. Grace +8 more
TL;DR: In this Review, what is known about CVD burden, risk factors, and treatment strategies for individuals living in the EMR are summarized to aid decision-makers when devising strategies on how to improve CVD prevention and management in this region.
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Guidelines for Acute Decompensated Heart Failure Treatment
Robert J. DiDomenico,Hayley Y. Park,Mary Ross Southworth,Heather M Eyrich,Richard K. Lewis,Jamie M Finley,Glen T. Schumock +6 more
TL;DR: The development of guidelines for the treatment of acute decompensated heart failure in the emergency department/observation unit (ED-OU) setting for hospitals that are part of a group purchasing organization (GPO) is described.
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