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ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: Executive summary and recommendations: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on the management of patients with unstable angina)

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TLDR
The present guidelines supersede the 1994 guidelines and summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy.
Abstract
The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Practice Guidelines was formed to make recommendations regarding the diagnosis and treatment of patients with known or suspected cardiovascular disease. Coronary artery disease (CAD) is the leading cause of death in the United States. Unstable angina (UA) and the closely related condition non–ST-segment elevation myocardial infarction (NSTEMI) are very common manifestations of this disease. These life-threatening disorders are a major cause of emergency medical care and hospitalizations in the United States. In 1996, the National Center for Health Statistics reported 1 433 000 hospitalizations for UA or NSTEMI. In recognition of the importance of the management of this common entity and of the rapid advances in the management of this condition, the need to revise guidelines published by the Agency for Health Care Policy and Research (AHCPR) and the National Heart, Lung and Blood Institute in 1994 was evident. This Task Force therefore formed the current committee to develop guidelines for the management of UA and NSTEMI. The present guidelines supersede the 1994 guidelines. The customary ACC/AHA classifications I, II, and III summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy: Class I: Conditions for which there is evidence and/or general agreement that a given procedure or treatment is useful and effective . Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment. Class IIa: Weight of evidence/opinion is in favor of usefulness/efficacy. Class IIb: Usefulness/efficacy is less well established by evidence/opinion. Class III: Conditions for which there is evidence and/or general agreement that the procedure/treatment is not useful/effective and in some cases may be harmful. The weight of the evidence was ranked highest (A) if the data …

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Journal ArticleDOI

The TIMI risk score for unstable angina/non–ST-elevation MI: a method for prognostication and therapeutic decision making

TL;DR: Many attempts to estimate a gradient of risk among patients with UA/NSTEMI focus on a single variable, such as presence or absence of electrocardiographic (ECG) changes or elevated serum cardiac markers.
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Usefulness of in-hospital prescription of statin agents after angiographic diagnosis of coronary artery disease in improving continued compliance and reduced mortality

TL;DR: In this article, the authors showed that after angiographic diagnosis of coronary artery disease, prescription of appropriate statin therapy at the time of hospital discharge improves long-term statin compliance and may significantly enhance survival.
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Comparison of the sensitivity and specificity of exercise electrocardiography in biased and unbiased populations of men and women

TL;DR: The accuracy of exercise electrocardiography is lower in women than men irrespective of whether a biased or an unbiased group is used, however, these differences cannot be explained on the basis of sex-related differences in posttest referral bias.
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Prognostic Role of Troponin T Versus Troponin I in Unstable Angina Pectoris for Cardiac Events With Meta-Analysis Comparing Published Studies

TL;DR: Troponin T and I show similar prognostic significance for acute myocardial infarction or death in the same patients with UAP, and this supports a role in risk stratification.
Journal ArticleDOI

Atherosclerosis in aortocoronary bypass grafts. Morphologic study and risk factor analysis 6 to 12 years after surgery.

TL;DR: Segments of aortocoronary vein grafts from a selective group of 42 patients who underwent a second revascularization procedure or came to autopsy 6 to 12 years after coronary bypass surgery were studied, finding atherosclerosis appears to be an important factor in late graft failure.
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