ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: Executive summary and recommendations: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on the management of patients with unstable angina)
Eugene Braunwald,Elliott M. Antman,John W. Beasley,Robert M. Califf,Melvin D. Cheitlin,Judith S. Hochman,Robert H. Jones,Dean J. Kereiakes,Joel Kupersmith,Thomas N. Levin,Carl J. Pepine,John W. Schaeffer,Earl E. Smith,David E Steward,Pierre Theroux,Raymond J. Gibbons,Joseph S. Alpert,David P. Faxon,Valentin Fuster,Gabriel Gregoratos,Loren F. Hiratzka,Alice K. Jacobs,Sidney C. Smith +22 more
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The present guidelines supersede the 1994 guidelines and summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy.Abstract:
The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Practice Guidelines was formed to make recommendations regarding the diagnosis and treatment of patients with known or suspected cardiovascular disease. Coronary artery disease (CAD) is the leading cause of death in the United States. Unstable angina (UA) and the closely related condition non–ST-segment elevation myocardial infarction (NSTEMI) are very common manifestations of this disease. These life-threatening disorders are a major cause of emergency medical care and hospitalizations in the United States. In 1996, the National Center for Health Statistics reported 1 433 000 hospitalizations for UA or NSTEMI. In recognition of the importance of the management of this common entity and of the rapid advances in the management of this condition, the need to revise guidelines published by the Agency for Health Care Policy and Research (AHCPR) and the National Heart, Lung and Blood Institute in 1994 was evident. This Task Force therefore formed the current committee to develop guidelines for the management of UA and NSTEMI. The present guidelines supersede the 1994 guidelines.
The customary ACC/AHA classifications I, II, and III summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy:
Class I: Conditions for which there is evidence and/or general agreement that a given procedure or treatment is useful and effective .
Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
Class IIa: Weight of evidence/opinion is in favor of usefulness/efficacy.
Class IIb: Usefulness/efficacy is less well established by evidence/opinion.
Class III: Conditions for which there is evidence and/or general agreement that the procedure/treatment is not useful/effective and in some cases may be harmful.
The weight of the evidence was ranked highest (A) if the data …read more
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Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management.
TL;DR: The incidence of cardiotoxicity caused by commonly used chemotherapeutic agents as well as the pathogenesis, diagnosis, management, and prevention of these cardiovascular side effects are reviewed.
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2012 ACCF/AHA focused update of the guideline for the management of patients with unstable angina/non-ST-elevation myocardial infarction (updating the 2007 guideline and replacing the 2011 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.
Hani Jneid,Jeffrey L. Anderson,R. Scott Wright,Cynthia D. Adams,Charles R. Bridges,Donald E. Casey,Steven M. Ettinger,Francis M. Fesmire,Theodore G. Ganiats,A. Michael Lincoff,Eric D. Peterson,George J. Philippides,Pierre Theroux,Nanette K. Wenger,James P. Zidar +14 more
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Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
Marco Valgimigli,Andrea Gagnor,Paolo Calabrò,Enrico Frigoli,Sergio Leonardi,Tiziana Zaro,Paolo Rubartelli,Carlo Briguori,Giuseppe Andò,Alessandra Repetto,Ugo Limbruno,Bernardo Cortese,Paolo Sganzerla,Alessandro Lupi,Mario Galli,Salvatore Colangelo,Salvatore Ierna,Arturo Ausiello,Patrizia Presbitero,Gennaro Sardella,Ferdinando Varbella,Giovanni Esposito,Andrea Santarelli,Simone Tresoldi,Marco Stefano Nazzaro,Antonio Zingarelli,Nicoletta De Cesare,Stefano Rigattieri,Paolo Tosi,Cataldo Palmieri,Salvatore Brugaletta,Sunil V. Rao,Dik Heg,Martina Rothenbühler,Pascal Vranckx,Peter Jüni +35 more
TL;DR: In patients with acute coronary syndrome undergoing invasive management, radial as compared with femoral access reduces net adverse clinical events, through a reduction in major bleeding and all-cause mortality.
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