Actin-Based Cell Motility and Cell Locomotion
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This work acknowledges key intellectual contributions from Jody Rosenblatt and Julie Theriot (protrusion, Listeria motility) and attempted to fairly represent different laboratories, systems, and opinions.About:
This article is published in Cell.The article was published on 1996-02-09 and is currently open access. It has received 1574 citations till now.read more
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Wound Healing--Aiming for Perfect Skin Regeneration
TL;DR: Details of how these signals control wound cell activities are beginning to emerge, and studies of healing in embryos have begun to show how the normal adult repair process might be readjusted to make it less like patching up and more like regeneration.
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Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
TL;DR: A coupling between physical adhesion and developmental signaling provides a mechanism to tightly integrate physical aspects of tissue morphogenesis with cell growth and differentiation, a coordination that is essential to achieve the intricate patterns of cells in tissues.
Journal ArticleDOI
Biological materials: Structure and mechanical properties
TL;DR: In this article, the basic building blocks are described, starting with the 20 amino acids and proceeding to polypeptides, polysaccharides, and polyprotein-saccharide.
Journal ArticleDOI
Epidermal growth factor receptor: mechanisms of activation and signalling.
Robert N. Jorissen,Francesca Walker,Francesca Walker,Normand Pouliot,Thomas P. J. Garrett,Thomas P. J. Garrett,Colin W. Ward,Colin W. Ward,Antony W. Burgess,Antony W. Burgess +9 more
TL;DR: The structure and function of the EGFR is reviewed, from ligand binding to the initiation of intracellular signalling pathways that lead to changes in the biochemical state of the cell.
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Molecular Mechanisms Controlling Actin Filament Dynamics in Nonmuscle Cells
TL;DR: How motile cells regulate actin filament assembly at their leading edge is reviewed, including how Arp2/3 complex is incorporated into the network, and new filaments are capped rapidly, so that activated Arp1/2 complex must be supplied continuously to keep the network growing.
References
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Cell Migration: A Physically Integrated Molecular Process
TL;DR: The authors are grateful for financial support from the National Institutes of Health (grants GM23244 and GM53905), and to very helpful comments on the manuscript from Elliot Elson, Vlodya Gelfand, Paul Matsudaira, Julie Theriot, and Sally Zigmond.
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Actin and Actin-Binding Proteins. A Critical Evaluation of Mechanisms and Functions
Thomas D. Pollard,John A. Cooper +1 more
TL;DR: The present study focuses on the development of binding proteins that bind to the sides of ACTIN FILAMENTS and their applications in the context of nanofiltration.
Journal ArticleDOI
Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.
TL;DR: Once inside a host cell, the infecting Listeria and their progeny can spread from cell to cell by remaining intracellular and thus bypass the humoral immune system of the organism.
Journal ArticleDOI
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination
TL;DR: Data are presented demonstrating that integration of a transfected plasmid by homologous recombination occurs in the motile eukaryotic cell Dictyostelium discoideum, providing genetic proof that the intact myosin molecule is required for cytokinesis and not for karyokinesis.
Journal ArticleDOI
Cellular motions and thermal fluctuations: the Brownian ratchet
TL;DR: A model for how chemical reactions generate protrusive forces by rectifying Brownian motion is presented, which drives a number of intracellular processes, including filopodial protrusion, propulsion of the bacterium Listeria, and protein translocation.
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