Acute control of fatty acid synthesis by cyclic AMP in the chick liver cell: possible site of inhibition of citrate formation.
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Results implicate a second site of inhibition of fatty acid synthesis by Bt(2)cAMP that involves the utilization, but not the production, of cytoplasmic acetyl-CoA.-Clarke, S. D., P. A. Watkins, and M. Lane.About:
This article is published in Journal of Lipid Research.The article was published on 1979-11-01 and is currently open access. It has received 45 citations till now. The article focuses on the topics: Mitochondrial pyruvate transport & Glycolysis.read more
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Fructose 2,6-bisphosphate 2 Years After its Discovery
TL;DR: Fru-2,6-P2 is not an intermediary metabolite of glycolysis, but its most potent regulator and its potential role in the control of metabolism in various organisms is delineated.
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Fructose 2,6-bisphosphate
TL;DR: Fructose 2,6-biphosphate is an intracellular signal which signifies that glucose is abundant; in this respect, its action is opposed to that of cyclic AMP.
Journal ArticleDOI
Short-term Hormonal Control of Hepatic Lipogenesis
TL;DR: The ability to keep large amounts of triacylglycerols on board would not be useful, however, if it were not possible to quickly and efficiently stop diverting foodstuffs into triacyglycerol formation and to start utilizing these compounds to provide the energy necessary to synthesize ATP as mentioned in this paper.
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Formation and turnover of triglyceride-rich vesicles in the chick liver cell. Effects of cAMP and carnitine on triglyceride mobilization and conversion to ketones.
Robert A. Mooney,M D Lane +1 more
TL;DR: Mechanisms are presented which could account for the effects of cAMP and carnitine on the turnover of vesicle triglyceride both at the level of lipolysis and the utilization of the released fatty acids by mitochondria.
References
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A revision of the Schoenheimer-Sperry method for cholesterol determination
Warren M. Sperry,Merrill Webb +1 more
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Regulation of Hepatic Acetyl Coenzyme A Carboxylase by Phosphorylation and Dephosphorylation
Curtis A. Carlson,Ki-Han Kim +1 more
TL;DR: In this paper, a partially purified CoA carboxylase (EC 6.4.1) was inactivated by ATP in a reaction which was both time and temperature dependent, and the inactivation was independent of adenosine 3′,5′-monophosphate.
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Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate (Short Communication)
TL;DR: It is concluded that a specific carrier is involved in membrane transport of pyruvate and that the plasma-membrane carrier may also be involved in lactate transport.
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Rapid separation of particulate components and soluble cytoplasm of isolated rat-liver cells
P.F. Zuurendonk,Joseph M. Tager +1 more
TL;DR: A method is described for the rapid separation of mitochondria (plus other particulate components) from the soluble cytoplasm of isolated rat-liver cells and found that the pellet contained more than 90% of the total adenylate kinase and glutamate dehydrogenase activities and the supernatant at least 80%" of the lactate dehydration activity.