Journal ArticleDOI
Adverse Childhood Experiences Among Inpatient Youths with Severe and Early-Onset Psychiatric Disorders: Prevalence and Clinical Correlates.
TLDR
Youths who had been exposed to ACEs did not exhibit a more severe presentation or a poorer response to treatment compared to others, either in the bipolar group or in the catatonic group.Abstract:
This study aimed to determine the prevalence and the clinical correlates of Adverse Childhood Experiences (ACEs) among 158 inpatient youths with two types of severe psychiatric disorders. ACEs were retrospectively collected with the ACEs scale and the List of Threatening Experiences Questionnaire in 77 patients hospitalized for a catatonic syndrome (average age 15.2 years) and 81 for a manic or mixed episode (average age 15.7 years). ACEs were frequent in youths suffering from bipolar disorder type I (BD-I) (58 %) and from catatonia (57 %), with around one quarter exposed to severe abuse (i.e., physical/sexual/emotional abuse or physical/emotional neglect). Youths with BD-I were more likely to be exposed to family violence compared to those with catatonia. Youths who had been exposed to ACEs did not exhibit a more severe presentation or a poorer response to treatment compared to others, either in the bipolar group or in the catatonic group.read more
Citations
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The Course of Subthreshold Bipolar Disorder in Youth: Diagnostic Progression From Bipolar Disorder Not Otherwise Specified
TL;DR: Children and adolescents referred with mood symptoms that meet operationalized criteria for BP-NOS, particularly those with a family history of BP, frequently progress to BP-I or BP-II, and conversion was associated with greater intensity of hypomanic symptoms and with greater exposure to specialized, intensive outpatient psychosocial treatments.
Journal ArticleDOI
The impact of childhood trauma on developing bipolar disorder: current understanding and ensuring continued progress
TL;DR: This review first outlines the most prominent hypotheses linking CT exposure and the onset of BD, followed by a discussion of original studies that investigated the role of CT in young people with early-onset BD, youths at increased risk of developing BD, or youngsters with BD with a focus on subclinical and clinical outcome measures.
Journal ArticleDOI
The Relationship Between ACEs, Trauma-Related Psychopathology and Resilience in Vulnerable Youth: Implications for Screening and Treatment
TL;DR: Regression analysis showed that resilience had a protective influence: as ACE distress increased, those high in resilience reported less somatization or depression, and underscore the importance of assessing resilience in conjunction.
Journal ArticleDOI
Are youths with disruptive mood dysregulation disorder different from youths with major depressive disorder or persistent depressive disorder
Xavier Benarous,Johanne Renaud,Jean Jacques Breton,David Cohen,Réal Labelle,Jean-Marc Guilé,Jean-Marc Guilé +6 more
TL;DR: Youths with DMDD share several clinical features with youths with MDD and PDD, and further studies are required to determine the developmental trajectories and the benefits of expanding pharmacotherapy for DD to D MDD.
References
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Journal ArticleDOI
Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study
Vincent J. Felitti,Robert F. Anda,Dale F. Nordenberg,David F. Williamson,Alison M. Spitz,Valerie J. Edwards,Mary P. Koss,James S. Marks +7 more
TL;DR: For example, this article found a strong relationship between the breadth of exposure to abuse or household dysfunction during childhood and multiple risk factors for several of the leading causes of death in adults.
Journal ArticleDOI
Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
TL;DR: The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria.
Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
TL;DR: The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.
Journal ArticleDOI
Diagnostic Interview for Genetic Studies: Rationale, Unique Features, and Training
John I. Nurnberger,Mary C. Blehar,Charles A. Kaufmann,Carolyn York-Cooler,Sylvia G. Simpson,Jill M. Harkavy-Friedman,Joanne B. Severe,Dolores Malaspina,Theodore Reich +8 more
TL;DR: The DIGS is designed to be employed by interviewers who exercise significant clinical judgment and who summarize information in narrative form as well as in ratings, and should be useful as part of archival data gathering for genetic studies of major affective disorders, schizophrenia, and related conditions.
Journal ArticleDOI
Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication I: Associations With First Onset of DSM-IV Disorders
Jennifer Greif Green,Katie A. McLaughlin,Patricia A. Berglund,Michael J. Gruber,Nancy A. Sampson,Alan M. Zaslavsky,Ronald C. Kessler +6 more
TL;DR: This article examined the joint associations of 12 retrospectively reported CAs with the first onset of DSM-IV disorders in the National Comorbidity Survey Replication using substantively complex multivariate models.