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Journal ArticleDOI

Analytical and environmental applications of nanoparticles as enzyme mimetics

TLDR
Recently, the intrinsic enzyme-like activity of nanoparticles (NPs) has become a growing area of interest as mentioned in this paper, and these enzymes are stable against denaturing, low in cost, and highly resistant to high concentrations of substrate.
Abstract
Recently, the intrinsic enzyme-like activity of nanoparticles (NPs) has become a growing area of interest. Compared with natural enzymes, these enzyme-like NPs are stable against denaturing, low in cost, and highly resistant to high concentrations of substrate. These advantages make them promising in various applications. In this review, we focus on recent advances in NPs as enzyme mimetics and their analytical and environmental applications. We pay special attention to the enzyme-like activity of magnetic NPs, cerium-oxide NPs, noble-metal NPs, carbon and other nanomaterials.

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Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

TL;DR: This review discusses various nanomaterials that have been explored to mimic different kinds of enzymes and covers their kinetics, mechanisms and applications in numerous fields, from biosensing and immunoassays, to stem cell growth and pollutant removal.
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Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes

TL;DR: Graphene oxide could serve as a modulator to greatly improve the catalytic activity of lysozyme-stabilized gold nanoclusters at neutral pH, which will have great potential for applications in biological systems and the incorporation of modulator into artificial enzymes can offer a facile but highly effective way to improve their overall catalytic performance.
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Nanozymes in bionanotechnology: from sensing to therapeutics and beyond

TL;DR: The diverse applications of nanozymes, which range from sensing, imaging, and therapeutics, to logic gates, pollutant removal, water treatment, etc, are discussed, and the current challenges facing nanozyme research are addressed.

Magnetite-containing spherical silica nanoparticles for biocatalysis and bioseparations (vol 76, pg 1316, 2004)

TL;DR: Experiments have proved that these catalysts have a long-term stability toward temperature and pH change, as compared to free enzyme molecules and a magnetic-separation immunoassay system was developed for the quantitative determination of gentamicin.
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Carbon Nanozymes: Enzymatic Properties, Catalytic Mechanism, and Applications.

TL;DR: Recent progress of CNMs based artificial enzymes, focusing on those with peroxidase-like activity, has been summarized and the enzymatic properties, catalytic mechanisms, and novel applications of CNM nanozymes in sensing, therapy, and environmental engineering are discussed in detail.
References
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Journal ArticleDOI

Chemistry and properties of nanocrystals of different shapes.

TL;DR: The interest in nanoscale materials stems from the fact that new properties are acquired at this length scale and, equally important, that these properties are equally important.
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Magnetic nanoparticles: Synthesis, protection, functionalization, and application

TL;DR: This review focuses on the synthesis, protection, functionalization, and application of magnetic nanoparticles, as well as the magnetic properties of nanostructured systems.
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Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications

TL;DR: Practical Interests of Magnetic NuclearRelaxation for the Characterization of Superparamagnetic Colloid, and Use of Nanoparticles as Contrast Agents forMRI20825.
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Chemically Derived, Ultrasmooth Graphene Nanoribbon Semiconductors

TL;DR: A chemical route to produce graphene nanoribbons with width below 10 nanometers was developed, as well as single ribbons with varying widths along their lengths or containing lattice-defined graphene junctions for potential molecular electronics.
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Intrinsic peroxidase-like activity of ferromagnetic nanoparticles

TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
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