Journal ArticleDOI
Anthrax as a Biological Weapon Medical and Public Health Management
Thomas V. Inglesby,Donald A. Henderson,John G. Bartlett,Michael S. Ascher,Edward M. Eitzen,Arthur M. Friedlander,Jerome Hauer,Joseph E. McDade,Michael T. Osterholm,Gerald W. Parker,Trish M. Perl,Philip K. Russell,Kevin Tonat +12 more
TLDR
A consensus-based recommendation for measures to be taken by medical and public health professionals following the use of anthrax as a biological weapon against a civilian population was developed by a working group of 21 representatives from staff of major academic medical centers and research as mentioned in this paper.Abstract:
Objective To develop consensus-based recommendations for measures to be taken by medical and public health professionals following the use of anthrax as a biological weapon against a civilian population. Participants The working group included 21 representatives from staff of major academic medical centers and research, government, military, public health, and emergency management institutions and agencies. Evidence MEDLINE databases were searched from January 1966 to April 1998, using the Medical Subject Headings anthrax, Bacillus anthracis, biological weapon, biological terrorism, biological warfare, and biowarfare. Review of references identified by this search led to identification of relevant references published prior to 1966. In addition, participants identified other unpublished references and sources. Consensus Process The first draft of the consensus statement was a synthesis of information obtained in the formal evidence-gathering process. Members of the working group provided formal written comments which were incorporated into the second draft of the statement. The working group reviewed the second draft on June 12, 1998. No significant disagreements existed and comments were incorporated into a third draft. The fourth and final statement incorporates all relevant evidence obtained by the literature search in conjunction with final consensus recommendations supported by all working group members. Conclusions Specific consensus recommendations are made regarding the diagnosis of anthrax, indications for vaccination, therapy for those exposed, postexposure prophylaxis, decontamination of the environment, and additional research needs.read more
Citations
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Journal ArticleDOI
2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings.
TL;DR: The ability of hospital ventilation systems to filter Aspergillus and other fungi following a building implosion and the impact of bedside design and furnishing on nosocomial infections are investigated.
Journal ArticleDOI
Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults
John G. Bartlett,Scott F. Dowell,Lionel A. Mandell,Thomas M. File,Daniel M. Musher,Michael J. Fine +5 more
TL;DR: This study highlights the need to understand more fully the role of Epstein-Barr virus in the development of central giant cell granuloma and its role in the immune system.
Journal ArticleDOI
Practice Guidelines for the Diagnosis and Management of Skin and Soft-Tissue Infections
Dennis L. Stevens,Alan L. Bisno,Henry F. Chambers,Henry F. Chambers,E. Dale Everett,Patchen Dellinger,Ellie J. C. Goldstein,Sherwood L. Gorbach,Jan V. Hirschmann,Jan V. Hirschmann,Edward L. Kaplan,Jose G. Montoya,Jose G. Montoya,Jose G. Montoya,James C. Wade +14 more
TL;DR: It is the recommendation of this committee that patients with soft-tissue infection be distinguished by signs and symptoms of systemic toxicity (e.g., fever or hypothermia, tachycardia [heart rate,] and so on).
Journal ArticleDOI
Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America
Dennis L. Stevens,Alan L. Bisno,Henry F. Chambers,E. Patchen Dellinger,Ellie J. C. Goldstein,Sherwood L. Gorbach,Jan V. Hirschmann,Sheldon L. Kaplan,Jose G. Montoya,James C. Wade,R. M. Alden +10 more
TL;DR: This guideline addresses the wide array of SSTIs that occur in this population and emphasizes the importance of clinical skills in promptly diagnosing SSTI, identifying the pathogen, and administering effective treatments in a timely fashion.
Journal ArticleDOI
Botulinum Toxin as a Biological Weapon: Medical and Public Health Management
Stephen S. Arnon,Robert Schechter,Thomas V. Inglesby,Donald A. Henderson,John G. Bartlett,Michael S. Ascher,Edward M. Eitzen,Anne D. Fine,Jerome Hauer,Marcelle Layton,Scott R. Lillibridge,Michael T. Osterholm,Tara O'Toole,Gerald W. Parker,Trish M. Perl,Philip K. Russell,David L. Swerdlow,Kevin Tonat +17 more
TL;DR: People potentially exposed to botulinum toxin should be closely observed, and those with signs of botulism require prompt treatment with antitoxin and supportive care that may include assisted ventilation for weeks or months.
References
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AHFS Drug Information
TL;DR: AHFS (R) Drug Information 2017 is the most comprehensive evidence-based source of drug information complete with therapeutic guidelines and off-label uses and helps protect your patients and your practice.
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The Sverdlovsk anthrax outbreak of 1979
Matthew Meselson,Jeanne Guillemin,Martin Hugh-Jones,Alexander Langmuir,Ilona Popova,Alexis Shelokov,Olga Yampolskaya +6 more
TL;DR: It is concluded that the escape of an aerosol of anthrax pathogen at the military facility caused the outbreak of Sverdlovsk and that most victims worked or lived in a narrow zone extending from a military facility to the southern city limit.
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Clinical Recognition and Management of Patients Exposed to Biological Warfare Agents
Franz Dr,Peter B. Jahrling,Arthur M. Friedlander,McClain Dj,Hoover Dl,Bryne Wr,Julie A. Pavlin,George W. Christopher,Edward M. Eitzen +8 more
TL;DR: An updated primer on 11 classic BW and potential terrorist agents is provided to increase the likelihood of their being considered in a differential diagnosis.
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Biological warfare : A historical perspective
TL;DR: The history of biological warfare is difficult to assess because of a number of confounding factors, including difficulties in verification of alleged or attempted biological attacks, the use of allegations of biological attacks for propaganda purposes, and the incidence of naturally occurring endemic or epidemic diseases during hostilities.
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The Economic Impact of a Bioterrorist Attack: Are Prevention and Postattack Intervention Programs Justifiable?
TL;DR: A model is constructed that compares the impact of three classic agents of biologic warfare when released as aerosols in the suburb of a major city and provides economic justification for preparedness measures.
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Thomas V. Inglesby,David T. Dennis,Donald A. Henderson,John G. Bartlett,Michael S. Ascher,Edward M. Eitzen,Anne D. Fine,Arthur M. Friedlander,Jerome Hauer,John F. Koerner,Marcelle Layton,Joseph E. McDade,Michael T. Osterholm,Tara O'Toole,Gerald W. Parker,Trish M. Perl,Philip K. Russell,Monica Schoch-Spana,Kevin Tonat +18 more