Journal ArticleDOI
Antimicrobial usage in dogs and cats in first opinion veterinary practices in the UK
Reads0
Chats0
TLDR
Data recorded in practice management systems were demonstrated to be a practical source for monitoring antimicrobial usage in pets and to contribute to the development of antimicrobial resistance and loss of efficacy of antimicrobials in veterinary settings.Abstract:
Objectives: To provide baseline data on patterns of antimicrobial usage in dogs and cats through the analysis of data stored in electronic practice management systems.
Methods: Clinical data from 11 first opinion veterinary practices were extracted for the year 2007. Descriptive statistical analysis was performed to assess the usage of antimicrobials.
Results: Widespread usage of systemic broad-spectrum antimicrobials was observed. Antimicrobials most frequently used in both species were potentiated amoxicillin (44·4% and 46.1% in cats and dogs, respectively) and amoxicillin (14·3% and 20·7%). Cephalexin (13·4%) and cefovecin (15·0%) were also commonly used in dogs and cats, respectively. Systemic critically important antimicrobials in human medicine were widely used in dogs (60·5%) and cats (82·7%). Topical antimicrobials used in both species included fusidic acid (48·4% and 54·8%), framycetin (20·4% and 13·4%), polymyxin B (12·6% and 9·3%) and neomycin (6·5% and 6·6%).
Clinical Significance: Inappropriate usage of broad-spectrum antimicrobials may contribute to the development of antimicrobial resistance and loss of efficacy of antimicrobials in veterinary settings. Data recorded in practice management systems were demonstrated to be a practical source for monitoring antimicrobial usage in pets.read more
Citations
More filters
Journal ArticleDOI
Antibiotics used most commonly to treat animals in Europe
TL;DR: Clear ‘preferences’ between countries can be observed between antibiotic classes and the use of national formularies and guidance helps to drive responsible use of antibiotics and can significantly reduce the extent of use of CIAs.
Journal ArticleDOI
Public health risk of antimicrobial resistance transfer from companion animals
Constança Pomba,Merja Rantala,Christina Greko,Keith E. Baptiste,Boudewijn Catry,Engeline van Duijkeren,Ana Mateus,Miguel A. Moreno,Satu Pyörälä,Modestas Ružauskas,Pascal Sanders,Christopher Teale,E. John Threlfall,Zoltan Kunsagi,Jordi Torren-Edo,Helen Jukes,Karolina Törneke +16 more
TL;DR: In the face of the previously recognized microbiological hazards, a risk assessment tool could be applied in applications for marketing authorization for medicinal products for companion animals to allow the approval of new veterinary medicinal antimicrobials for which risk levels are estimated as acceptable for public health.
Journal ArticleDOI
Colistin in Pig Production: Chemistry, Mechanism of Antibacterial Action, Microbial Resistance Emergence, and One Health Perspectives.
TL;DR: The management of colistin resistance at the human-pig-environment interface requires the urgent use of the One Health approach for effective control and prevention.
Journal ArticleDOI
A Shared Population of Epidemic Methicillin-Resistant Staphylococcus aureus 15 Circulates in Humans and Companion Animals
Ewan M. Harrison,Lucy A. Weinert,Matthew T. G. Holden,John J. Welch,Katherine Wilson,Fiona J. E. Morgan,Simon R. Harris,Anette Loeffler,Amanda Boag,Sharon J. Peacock,Sharon J. Peacock,Gavin K. Paterson,Andrew S. Waller,Julian Parkhill,Mark A. Holmes +14 more
TL;DR: A shared population of an important and globally disseminated lineage of MRSA can infect both humans and companion animals without undergoing host adaptation, suggesting that companion animals might act as a reservoir for human infections.
Journal ArticleDOI
Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices
E L Buckland,Dan G. O’Neill,Jennifer F. Summers,Ana Mateus,David B. Church,L Redmond,Dave C. Brodbelt +6 more
TL;DR: A high frequency of AM usage in companion animal practice and for certain agents classified as of critical importance in human medicine is identified and the usefulness of veterinary practice electronic health records for studying AM usage is highlighted.
References
More filters
Journal ArticleDOI
A European study on the relationship between antimicrobial use and antimicrobial resistance.
S L A M Bronzwaer,Otto Cars,U Buchholz,Sigvard Mölstad,Wim Goettsch,Irene K. Veldhuijzen,Jacob L. Kool,Marc J.W. Sprenger,John E. Degener +8 more
TL;DR: It is shown that in Europe antimicrobial resistance is correlated with use of beta-lactam antibiotics and macrolides.
Journal ArticleDOI
Avoparcin used as a growth promoter is associated with the occurrence of vancomycin-resistant Enterococcus faecium on Danish poultry and pig farms
TL;DR: The similar findings in the two studies provide evidence in favour of a causal association between the use of avoparcin and the occurrence of VREF on farms, and suggest that food animals constitute a potential reservoir of infection for VREF in humans.
Journal ArticleDOI
World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies for the Use of Antimicrobials in Food Production Animals
Peter Collignon,John H. Powers,John H. Powers,John H. Powers,Tom Chiller,Awa Aidara-Kane,Frank Møller Aarestrup +6 more
TL;DR: The World Health Organization has developed and applied criteria to rank antimicrobials according to their relative importance in human medicine, and this ranking allows stakeholders to focus risk management efforts on drugs used in food animals that are the most important to human medicine and, thus, need to be addressed most urgently.
Journal ArticleDOI
The effects of antibiotic usage in food animals on the development of antimicrobial resistance of importance for humans in Campylobacter and Escherichia coli.
TL;DR: There is an urgent need to implement strategies for prudent use of antibiotics in food animal production to prevent further increases in the occurrence of antimicrobial resistance in food-borne human pathogenic bacteria such as Campylobacter and E. coli.
Journal ArticleDOI
Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners.
TL;DR: Owners of dogs affected by deep pyoderma often carry multiple antimicrobial-resistant strains of S. intermedius occurring in their dogs, which raises questions concerning the possible transfer of resistance genes from canine S. intermediaryus to human pathogenic staphylococci.