Journal ArticleDOI
Antioxidant activity of lipid-soluble phenolic diterpenes from rosemary
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TLDR
A high-performance liquid chromatography method for analyzing the phenolic diterpenes present in rosemary (Rosmarinus officinalis L.) and commercial rosemary extracts is reported in this article.Abstract:
A high-performance liquid chromatography method for analyzing the phenolic diterpenes present in rosemary (Rosmarinus officinalis L.) and commercial rosemary extracts is reported. Carnosic acid was the major phenolic diterpene present in rosemary leaves, with lesser amounts of 12-methoxycarnosic acid and carnosol. Several commercial rosemary extracts also were analyzed by this method, and in addition to these three compounds other phenolic diterpenes, such as 7-methoxyrosmanol, 7-methoxy-epirosmanol, and rosmanol, were found in some samples. These latter three compounds seem to be artifacts, produced from carnosic acid by oxidation and cyclization. The major phenolic diterpenes were isolated, and their relative antioxidatn activities in soybean oil were measured by the Rancimat. The potency of carnosic acid was more than twice that of any other compound. The antioxidant activity of pure carnosic acid was compared to butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), and tertiary butylhydroquinone (TBHQ) and was several times greater than BHT and BHA but less than TBHQ. Nuclear magnetic resonance data for several of the compounds that were incompletely characterized in previous literature are reported.read more
Citations
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Journal ArticleDOI
Absorption, Distribution and Elimination of Carnosic Acid, A Natural Antioxidant from Rosmarinus officinalis, in Rats
TL;DR: It was found that carnosic acid in vivo is present in its free form and that its main elimination route is the fecal route, which is absorbed into the bloodstream after oral administration in rats and is therefore bioavailable.
Journal ArticleDOI
Antioxidant Activity of Organic Extracts from Aqueous Infusions of Sage
Triantafillia Christina Matsingou,Nicolaos Petrakis,Maria Kapsokefalou,Athanasios Salifoglou +3 more
TL;DR: Polyphenolic and nonpolyphenolic substances present in the extracts arise as significant contributors to the observed antioxidant activity of the derived extracts and thus sage itself, and reflect the antioxidant potential of the aqueous infusions of sage toward reactive oxygen species generated through variable mechanisms of iron-promoted oxidative processes.
Journal ArticleDOI
Natural antioxidants in functional foods: from food safety to health benefits
TL;DR: Natural antioxidants such as tocopherols, ascorbic acid, rosemary extracts, lycopene and some flavonoids are now available to be added to foods in replacement of synthetic products.
Journal ArticleDOI
Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae : Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis
Dragana Božić,Dimitra Papaefthimiou,Kathleen Brückner,Ric C. H. de Vos,Constantinos A. Tsoleridis,Dimitra Katsarou,Antigoni Papanikolaou,Irini Pateraki,Fani Chatzopoulou,Eleni Dimitriadou,Stefanos Kostas,David Manzano,Ulschan Scheler,Albert Ferrer,Alain Tissier,Antonios M. Makris,Sotirios C. Kampranis,Angelos K. Kanellis +17 more
TL;DR: Carnosic acid is a phenolic diterpene with anti-tumour, anti-diabetic, antibacterial and neuroprotective properties that is produced by a number of species from several genera of the Lamiaceae family, including Salvia fruticosa and Rosmarinus officinalis.
Journal ArticleDOI
Relevance of phenolic diterpene constituents to antioxidant activity of supercritical CO2 extract from the leaves of rosemary
Chi Huang Chang,Charng Cherng Chyau,Chiu Lan Hsieh,Yen Ying Wu,Yaw Bee Ker,Hau Yang Tsen,Robert Y. Peng +6 more
TL;DR: Results indicate that an ideal extraction process was obtained at 5000 psi and 80°C with an extraction yield of 4.27% (w/w) and rich in phenolic antioxidants CA and CAL as contents of 35.23 and 0.46 mg g−1 in extract, respectively.
References
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Journal ArticleDOI
Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid
TL;DR: Both carnosol and carnosic acid stimulated DNA damage in the bleomycin assay but they scavenged hydroxyl radicals in the deoxyribose assay.
Journal ArticleDOI
Antioxidant Constituents in Sage (Salvia officinalis)
TL;DR: The antioxidant compounds of oleoresin of sage (Salvia officinalis) were separated by column chromatography and high-performance liquid chromatography as discussed by the authors, and the major compounds were identified by IR, MS, and 1 H NMR spectrometry as carnosol, carnosic acid, rosmadial, rosmanol, epirosmanol and methyl carnosate.
MonographDOI
The Maillard reaction in foods and nutrition
TL;DR: In this article, the authors present a review of the sensory properties of almost 450 Maillard reaction products, with an emphasis on mutagen production and food technology aspects, with emphasis on lysine losses.
Journal ArticleDOI
Effects of rosemary extracts and major constituents on lipid oxidation and soybean lipoxygenase activity
TL;DR: In this article, a reverse-phase high-performance liquid chromatography system was used to quantitate the content of carnosol, carnosic acid and ursolic acid in the rosemary extracts.