Book ChapterDOI
Applications of Hard and Soft Tissue Engineering in Dentistry
Mohammadreza Tahriri,Regine Torres,Emelia Karkazis,Alexander Karkazis,Rizwan Bader,Daryoosh Vashaee,Lobat Tayebi +6 more
- pp 179-193
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TLDR
This book chapter aims to address the advancement of tissue engineering for different dental hard and soft tissues, such as enamel, dentin, bone, periodontium, oral mucosa, and salivary glands.Abstract:
Tissue engineering is a novel and multidisciplinary field that intends to remake functional, sound tissues and organs to supplant unhealthy or dead tissues. The advancement of tissue engineering for dental tissues is promising, and different dental soft and hard tissues have been regenerated effectively in vitro, utilizing stem cells and scaffolds. In almost any tissue engineering application, there are various challenges and unanswered inquiries that should be settled for further advancements. It is expected that in the next few decades, the field of dentistry will be altered remarkably by the accessibility of novel tissue-engineered products in the dental industry. This book chapter aims to address the advancement of tissue engineering for different dental hard and soft tissues, such as enamel, dentin, bone, periodontium, oral mucosa, and salivary glands. Additionally, challenges in the advancement of tissue engineering and future trends have been summarized in this book chapter.read more
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Journal ArticleDOI
Nanotechnology, and scaffold implantation for the effective repair of injured organs: An overview on hard tissue engineering
Parinaz Abdollahiyan,Fatemeh Oroojalian,Maryam Hejazi,Miguel de la Guardia,Ahad Mokhtarzadeh +4 more
TL;DR: In this article, most advanced technical improvements, experiments, and future outlooks of hard tissue engineering are discussed, as well as their relevant additive manufacturing techniques, and a review of 3D bioprinting methods still have some uncertainties.
Journal ArticleDOI
Stem cells and common biomaterials in dentistry: a review study
TL;DR: In this paper , a review study examines three essential elements of tissue engineering in dentistry and clinical practice, including stem cells derived from the intra-and extra-oral sources, growth factors, and scaffolds.
Book ChapterDOI
Biomaterials for Hard Tissue Engineering: Concepts, Methods, and Applications
TL;DR: In this article, the authors provide a brief description of the importance of biomaterials in the field of hard tissue regeneration, recent advances of biommaterials and strategies to fabricate biomaterial-based scaffolds for bone and tooth regeneration, significance of 3D bioprinting in hard tissue engineering, etc.
References
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Journal ArticleDOI
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TL;DR: Differentiation of the osteoprogenitor cell is elicited by local alterations in cell metabolic cycles that are as yet uncharacterized and may transfer collagenolytic activity to the substrate to cause dissolution of the matrix.
Journal ArticleDOI
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Journal ArticleDOI
Challenges in tissue engineering
TL;DR: A brief overview on the current tissue engineering is given, covering the fundamentals and applications, and some critical problems to be resolved for the advances of tissue engineering are addressed from the engineering point of view.
Journal ArticleDOI
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Journal ArticleDOI
Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial.
Myron Nevins,William V. Giannobile,Michael K. McGuire,Richard T. Kao,James T. Mellonig,James E. Hinrichs,Bradley S. McAllister,Kevin S. Murphy,Pamela K. McClain,Marc L. Nevins,David W. Paquette,Thomas J. Han,Michael S. Reddy,Philip T. Lavin,Robert J. Genco,Samuel E. Lynch +15 more
TL;DR: The study demonstrated that the use of rhPDGF-BB was safe and effective in the treatment of periodontal osseous defects and is the largest prospective, randomized, triple-blinded, and controlled pivotal clinical trial reported to date assessing a putativeperiodontal regenerative and wound healing therapy.