scispace - formally typeset
Journal ArticleDOI

Association of antiphospholipid antibodies with central nervous system disease in systemic lupus erythematosus

TLDR
It is confirmed that CNS disease in SLE is significantly associated with the presence of aPL antibodies, and the CNS manifestations can occur in about half of SLE patients without any other evidence of lupus activity.
About
This article is published in The American Journal of Medicine.The article was published on 1995-10-01. It has received 185 citations till now. The article focuses on the topics: Lupus erythematosus & Systemic lupus erythematosus.

read more

Citations
More filters
Journal ArticleDOI

The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes

TL;DR: The American College of Rheumatology Nomenclature for NPSLE provides case definitions for 19 neuropsychiatric syndromes seen in SLE, with reporting standards and recommendations for laboratory and imaging tests.
Journal Article

Neuropsychiatric manifestations in systemic lupus erythematosus: prevalence and association with antiphospholipid antibodies.

TL;DR: The new ACR criteria for NPSLE are useful to define NP manifestations in SLE with accuracy and are significantly associated with antiphospholipid antibodies, which are independently associated with CVD, headache, and seizures.
Journal ArticleDOI

Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study.

TL;DR: The most common clinical manifestations were arthritis, malar rash, nephritis, and central nervous system (CNS) disease, and patients with both renal and CNS disease had the highest SLE Disease Activity Index (SLEDAI) scores at diagnosis.
Journal ArticleDOI

Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations

TL;DR: Evidence supports the use of glucocorticoids alone or in combination with immunosuppressive therapy for SLE-related neuropsychiatric disease, and antiplatelet and/or anticoagulation therapy is recommended for NPSLE manifestations related to antiphospholipid antibodies.
References
More filters
Journal ArticleDOI

The 1982 revised criteria for the classification of systemic lupus erythematosus

TL;DR: The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification and showed gains in sensitivity and specificity.
Journal ArticleDOI

Thrombosis, abortion, cerebral disease, and the lupus anticoagulant.

Graham R. V. Hughes
- 15 Oct 1983 - 
TL;DR: Few diabetics register on the Disabled Persons Register, but those with disabling complications may find it advantageous to do so and to seek the advice of their local disablement resettlement officer.
Journal Article

Evaluation of the anti-cardiolipin antibody test: report of an international workshop held 4 April 1986.

TL;DR: This study shows that properly performed ELISA or SRIA assays can be used to provide an accurate, reproducible, and quantitative measure of IgG and IgM aCL concentration in serum samples.
Related Papers (5)