Journal ArticleDOI
Au@Pt core/shell nanorods with peroxidase- and ascorbate oxidase-like activities for improved detection of glucose
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TLDR
In this article, the relationship between apparent enzyme kinetic parameters and nanomaterials structure is investigated in order to rationally design the catalytic activity of the Au nanorods.Abstract:
Au nanorods @ Pt nanodots core/shell nanostructures, prepared by the Au nanorods (NRs)-mediated growth, exhibit dual functional enzyme-like (peroxidase and oxidase-like) activities. From the viewpoint of enzyme mimics, the relationship between apparent enzyme kinetic parameters and nanomaterials structure is investigated in order to rationally design the catalytic activity. Using peroxidase-like properties of the Au@Pt NRs, the determination of hydrogen peroxide (H2O2) was demonstrated with a limit of detection (LOD) of 4.5 × 10−5 M and a linear range of 4.5 × 10−5–1 × 10−3 M using o-phenylenediamine (OPD) as chromogenic substrate. Furthermore, in combination with highly specific reactions provided by natural enzymes, selective detections of glucose and lipophilic cholesterol were demonstrated with similar LODs and linear ranges. Additionally, owing to the specific oxidase-like activity of the Au@Pt NRs (ascorbate oxidase), interference of ascorbic acid in the detection of glucose could be eliminated. In conclusion, considering the flexibility in the design of nanomatererials, there is a lot of space to improve their activity and explore their potential applications, especially in relatively harsh conditions.read more
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Mechanisms of Oxidase and Superoxide Dismutation-like Activities of Gold, Silver, Platinum, and Palladium, and Their Alloys: A General Way to the Activation of Molecular Oxygen
Xiaomei Shen,Xiaomei Shen,Wenqi Liu,Xuejiao Gao,Zhang-Hui Lu,Xiaochun Wu,Xingfa Gao,Xingfa Gao +7 more
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MIL‐53(Fe): A Metal–Organic Framework with Intrinsic Peroxidase‐Like Catalytic Activity for Colorimetric Biosensing
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References
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Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Lizeng Gao,Jie Zhuang,Leng Nie,Jinbin Zhang,Yu Zhang,Ning Gu,Taihong Wang,Jing Feng,Dongling Yang,Sarah Perrett,Xiyun Yan +10 more
TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
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Oxidase activity of polymeric coated cerium oxide nanoparticles
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Positively-charged gold nanoparticles as peroxidiase mimic and their application in hydrogen peroxide and glucose detection
Yun Jv,Baoxin Li,Rui Cao +2 more
TL;DR: Positively-charged gold nanoparticles possess intrinsic peroxidase-like activity, and can catalyze oxidation of the per oxidase substrate 3,3,5,5-tetramethylbenzidine by H(2)O( 2) to develop a blue color in aqueous solution, thus providing a simple approach to colorimetric detection of H(1)O (2) and glucose.
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Journal ArticleDOI
Au@Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays.
Weiwei He,Ying Liu,Jinshan Yuan,Jun-Jie Yin,Xiaochun Wu,Xiaona Hu,Ke Zhang,Jianbo Liu,Chunying Chen,Yinglu Ji,Yuting Guo +10 more
TL;DR: Au@Pt nanostructures have advantages of low cost, easy preparation, better stability, and tunable catalytic activity (compared with HRP), which make them a promising enzyme mimetic candidate and may find potential applications in biocatalysis, bioassays, and nano-biomedicine.
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