'Big data', Hadoop and cloud computing in genomics
TLDR
An overview of cloud computing and big data technologies, and how such expertise can be used to deal with biology's big data sets is discussed, together with an overview of the current usage of Hadoop within the bioinformatics community.About:
This article is published in Journal of Biomedical Informatics.The article was published on 2013-10-01 and is currently open access. It has received 403 citations till now. The article focuses on the topics: Data-intensive computing & Big data.read more
Citations
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Big Data using Cloud Computing - Opportunities for Small and Medium-sized Enterprises
TL;DR: The current trends in the area of big data using cloud resources and how SMEs can take advantage of these technological trends are explored to benefit SMEs in identifying and exploring possible opportunities and also understanding the challenges in leveraging big data.
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Secure Data Deduplication With Reliable Key Management for Dynamic Updates in CPSS
TL;DR: This paper proposes a session-key-based convergent key management scheme, named SKC, to secure the dynamic update in the data deduplication and shows that both SKC and CKS can protect the confidentiality of the data and the convergentKey in the case of dynamic updates.
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Energy-efficient hadoop for big data analytics and computing: A systematic review and research insights
TL;DR: This paper reviews the studies on improving energy efficiency of Hadoop clusters and summarizes them in five categories including the energy-aware cluster node management,Energy-aware data management, Energy-aware resource allocation, energy- aware task scheduling and other energy-saving schemes.
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On the protection of consumer genomic data in the internet of living things
Raffaele Pizzolante,Arcangelo Castiglione,Bruno Carpentieri,Alfredo De Santis,Francesco Palmieri,Aniello Castiglione +5 more
TL;DR: In this paper, reversible watermarking techniques explicitly tailored for the characteristics of DNA microarray images are proposed to ensure the protection of such images in terms of authenticity and integrity, besides enabling the binding of those imaging data with other information related to them.
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Auditing Cloud-based Blockchain Accounting Systems
Deniz Appelbaum,Robert A. Nehmer +1 more
TL;DR: In this research, Nakamoto's seminal paper "Bitcoin: A Peer-to-Peer Electronic Cash System" (2008) is referred to to consider his proposed abstracted characteristics and how auditors could look at them.
References
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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna,Matthew Hanna,Eric Banks,Andrey Sivachenko,Kristian Cibulskis,Andrew Kernytsky,Kiran V. Garimella,David Altshuler,Stacey Gabriel,Mark J. Daly,Mark A. DePristo +10 more
TL;DR: The GATK programming framework enables developers and analysts to quickly and easily write efficient and robust NGS tools, many of which have already been incorporated into large-scale sequencing projects like the 1000 Genomes Project and The Cancer Genome Atlas.
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Cramming More Components Onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as mentioned in this paper. But the biggest potential lies in the production of large systems.
Journal Article
Cramming More Components onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as discussed by the authors. But the biggest potential lies in the production of large systems.
Book
Big data: The next frontier for innovation, competition, and productivity
TL;DR: The amount of data in the authors' world has been exploding, and analyzing large data sets will become a key basis of competition, underpinning new waves of productivity growth, innovation, and consumer surplus, according to research by MGI and McKinsey.
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Galaxy: A platform for interactive large-scale genome analysis
Belinda Giardine,Cathy Riemer,Ross C. Hardison,Richard Burhans,Laura Elnitski,Prachi Shah,Prachi Shah,Yi Zhang,Daniel Blankenberg,Istvan Albert,James Taylor,Webb Miller,W. James Kent,Anton Nekrutenko +13 more
TL;DR: An interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results.