'Big data', Hadoop and cloud computing in genomics
TLDR
An overview of cloud computing and big data technologies, and how such expertise can be used to deal with biology's big data sets is discussed, together with an overview of the current usage of Hadoop within the bioinformatics community.About:
This article is published in Journal of Biomedical Informatics.The article was published on 2013-10-01 and is currently open access. It has received 403 citations till now. The article focuses on the topics: Data-intensive computing & Big data.read more
Citations
More filters
Journal ArticleDOI
Emergence of Healthcare 4.0 and Blockchain into Secure Cloud-based Electronic Health Records Systems: Solutions, Challenges, and Future Roadmap
TL;DR: This paper aims to present a systematic study of different blockchain-based solutions for the smart healthcare 4.0 system, the current research gaps, the challenges of implementing the blockchain- based secure healthcare system, and the future roadmap or solutions.
Journal ArticleDOI
Research of Big Data Based on the Views of Technology and Application
TL;DR: The development of technologies in big data analysis and storage is described and the trends and different values in commercial applications, manufacturing, biomedical science and other applications are analyzed.
Journal ArticleDOI
A Knowledge-Driven Geospatially Enabled Framework for Geological Big Data
TL;DR: A knowledge-driven geologic survey information smart-service platform (GSISSP) is established and shows that all the content that has known relationships or semantic associations can be mined with the assistance of multiple ontologies, thereby improving the accuracy and comprehensiveness of geological information discovery.
Proceedings ArticleDOI
A Novel Storage Architecture for Facilitating Efficient Analytics of Health Informatics Big Data in Cloud
TL;DR: A new big data storage architecture consisting of application cluster and a storage cluster to facilitate read/write/update speedup as well as data optimization is proposed.
Journal ArticleDOI
Ad hoc file systems for high-performance computing
André Brinkmann,Kathryn Mohror,Weikuan Yu,Philip Carns,Toni Cortes,Scott Klasky,Alberto Miranda,Franz-Josef Pfreundt,Robert Ross,Marc-André Vef +9 more
TL;DR: This paper presents results from the Dagstuhl Seminar 17202 “Challenges and Opportunities of User-Level File Systems for HPC” and discusses application scenarios as well as design strategies for ad hoc file systems using node-local storage media.
References
More filters
Journal ArticleDOI
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna,Matthew Hanna,Eric Banks,Andrey Sivachenko,Kristian Cibulskis,Andrew Kernytsky,Kiran V. Garimella,David Altshuler,Stacey Gabriel,Mark J. Daly,Mark A. DePristo +10 more
TL;DR: The GATK programming framework enables developers and analysts to quickly and easily write efficient and robust NGS tools, many of which have already been incorporated into large-scale sequencing projects like the 1000 Genomes Project and The Cancer Genome Atlas.
Journal ArticleDOI
Cramming More Components Onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as mentioned in this paper. But the biggest potential lies in the production of large systems.
Journal Article
Cramming More Components onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as discussed by the authors. But the biggest potential lies in the production of large systems.
Book
Big data: The next frontier for innovation, competition, and productivity
TL;DR: The amount of data in the authors' world has been exploding, and analyzing large data sets will become a key basis of competition, underpinning new waves of productivity growth, innovation, and consumer surplus, according to research by MGI and McKinsey.
Journal ArticleDOI
Galaxy: A platform for interactive large-scale genome analysis
Belinda Giardine,Cathy Riemer,Ross C. Hardison,Richard Burhans,Laura Elnitski,Prachi Shah,Prachi Shah,Yi Zhang,Daniel Blankenberg,Istvan Albert,James Taylor,Webb Miller,W. James Kent,Anton Nekrutenko +13 more
TL;DR: An interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results.