'Big data', Hadoop and cloud computing in genomics
TLDR
An overview of cloud computing and big data technologies, and how such expertise can be used to deal with biology's big data sets is discussed, together with an overview of the current usage of Hadoop within the bioinformatics community.About:
This article is published in Journal of Biomedical Informatics.The article was published on 2013-10-01 and is currently open access. It has received 403 citations till now. The article focuses on the topics: Data-intensive computing & Big data.read more
Citations
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Towards Building a Plant Cell Atlas
TL;DR: A Plant Cell Atlas (PCA) that maps molecular machineries to cellular and subcellular domains, follows their dynamic movements, and describes their interactions would accelerate discovery in plant science and help to solve imminent societal problems.
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Connectomics and new approaches for analyzing human brain functional connectivity.
R. Cameron Craddock,R. Cameron Craddock,Rosalia Tungaraza,Michael P. Milham,Michael P. Milham +4 more
TL;DR: This review describes several outstanding problems in brain functional connectomics with the goal of engaging researchers from a broad spectrum of data sciences to help solve these problems.
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Assessing and Exploiting Functional Diversity in Germplasm Pools to Enhance Abiotic Stress Adaptation and Yield in Cereals and Food Legumes
TL;DR: An integrated approach involving multiple stakeholders specializing in management and utilization of genetic resources, crop breeding, molecular biology and genomics, agronomy, stress tolerance, and reproductive/seed biology will help to address the global challenge of ensuring food security in the face of growing resource demands and climate change induced stresses.
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BAMHealthCloud: A biometric authentication and data management system for healthcare data in cloud
TL;DR: In this article, a behavioral biometric signature-based authentication mechanism is proposed to ensure the security of e-medical data access in cloud-based healthcare management system, which achieves high accuracy rate for secure data access and retrieval.
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Real-time business activity monitoring and analysis of process performance on big-data domains
TL;DR: A cloud-based architecture that leverages big-data technology to support performance analysis on any business domain, in a timely manner and regardless of the underlying concerns of the operational systems is introduced.
References
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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna,Matthew Hanna,Eric Banks,Andrey Sivachenko,Kristian Cibulskis,Andrew Kernytsky,Kiran V. Garimella,David Altshuler,Stacey Gabriel,Mark J. Daly,Mark A. DePristo +10 more
TL;DR: The GATK programming framework enables developers and analysts to quickly and easily write efficient and robust NGS tools, many of which have already been incorporated into large-scale sequencing projects like the 1000 Genomes Project and The Cancer Genome Atlas.
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Cramming More Components Onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as mentioned in this paper. But the biggest potential lies in the production of large systems.
Journal Article
Cramming More Components onto Integrated Circuits
TL;DR: Integrated circuits will lead to such wonders as home computers or at least terminals connected to a central computer, automatic controls for automobiles, and personal portable communications equipment as discussed by the authors. But the biggest potential lies in the production of large systems.
Book
Big data: The next frontier for innovation, competition, and productivity
TL;DR: The amount of data in the authors' world has been exploding, and analyzing large data sets will become a key basis of competition, underpinning new waves of productivity growth, innovation, and consumer surplus, according to research by MGI and McKinsey.
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Galaxy: A platform for interactive large-scale genome analysis
Belinda Giardine,Cathy Riemer,Ross C. Hardison,Richard Burhans,Laura Elnitski,Prachi Shah,Prachi Shah,Yi Zhang,Daniel Blankenberg,Istvan Albert,James Taylor,Webb Miller,W. James Kent,Anton Nekrutenko +13 more
TL;DR: An interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results.