Journal ArticleDOI
Bioactive Compounds Effective Against Type 2 Diabetes Mellitus: A Systematic Review
Chukwuebuka Egbuna,Chinaza Godswill Awuchi,Garima Kushwaha,Mithun Rudrapal,Kingsley C. Patrick-Iwuanyanwu,Omkar Singh,UE Odoh,Johra Khan,Jaison Jeevanandam,Suresh Kumarasamy,Vincent O. Chukwube,Mathiyazhagan Narayanan,Santwana Palai,Mihnea-Alexandru Găman,Chukwuemelie Zedech Uche,DS Ogaji,Nebechi Jane Ezeofor,Andrew G. Mtewa,Chinyere C. Patrick-Iwuanyanwu,Shyam Sundar Kesh,Chandan Shivamallu,K. Saravanan,Habibu Tijjani,Muhammad Akram,Jonathan C. Ifemeje,Michael Chinedu Olisah,Chukwudi Jude Chikwendu +26 more
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TLDR
In this paper, a systematic review investigated the bioactive compounds reported to possess activities against type 2 diabetes, and found that quercetin, Kaempferol, Rosmarinic acid, Cyanidin, Rutin, Catechin, Luteolin and Ellagic acid were the most cited bio-active compounds which all fall within the class of polyphenolic compounds.Abstract:
BACKGROUND Type 2 diabetes (adult onset diabetes) is the most common type of diabetes, accounting for around 90% of all diabetes cases with insulin resistance and insulin secretion defect. The key goal of anti-diabetic therapy is to increase the development of insulin, immunity and/or decrease the amount of blood glucose. While many synthetic compounds have been produced as antidiabetic agents, due to their side effects and limited effectiveness, their usefulness has been hindered. METHODS This systematic review investigated the bioactive compounds reported to possess activities against type 2 diabetes. Three (3) databases, PubMed, ScienceDirect and Google Scholar were searched for research articles published between January 2010 and October 2020. A total of 6464 articles were identified out of which 84 articles were identified to be elligible for the study. RESULT AND DISCUSSION From the data extracted, it was found that quercetin, Kaempferol, Rosmarinic acid, Cyanidin, Rutin, Catechin, Luteolin and Ellagic acid were the most cited bioactive compounds which all falls within the class of polyphenolic compounds. The major sources of these bioactive compounds includes citrus fruits, grapes, onions, berries, cherries, broccoli, honey, apples, green tea, Ginkgo biloba, St. John's wort, green beans, cucumber, spinach, tea, Rosmarinus officinalis, Aloe vera, Moringa oleifera, tomatoes, potatoes, oregano, lemon balm, thyme, peppermint, Ocimum basilicum, red cabbage, pears, olive oil and walnut.read more
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Environmental arsenic exposure and its contribution to human diseases, toxicity mechanism and management.
Md. Shiblur Rahaman,Md. Shiblur Rahaman,Md. Mostafizur Rahman,Nathan Mise,Md. Tajuddin Sikder,Gaku Ichihara,Md. Khabir Uddin,Masaaki Kurasaki,Sahoko Ichihara +8 more
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Caloric Restriction Mimetics in Nutrition and Clinical Trials.
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Fabrication, characterization, anti-inflammatory, and anti-diabetic activity of silver nanoparticles synthesized from Azadirachta indica kernel aqueous extract.
Nguyen Thuy Lan Chi,Mathiyazhagan Narayanan,Arunachalam Chinnathambi,Chandramohan Govindasamy,Baskar Subramani,Kathirvel Brindhadevi,T. Pimpimon,Surachai Pikulkaew +7 more
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Antioxidant, phytochemical, and therapeutic properties of medicinal plants: a review
TL;DR: A review of the antioxidant potential of some plants with medicinal properties beneficial to people, industries, and health institutions who desire their potential benefits is presented in this article , where a total of two hundred and fifty plants from the following families; Asteraceae, Combretaceae, Euphorbiaceae, Fabaceae, Lamiaceae, Moraceae and Malvaceae were reviewed.