N
Nathan Mise
Researcher at Jichi Medical University
Publications - 53
Citations - 2695
Nathan Mise is an academic researcher from Jichi Medical University. The author has contributed to research in topics: XIST & X chromosome. The author has an hindex of 21, co-authored 50 publications receiving 2227 citations. Previous affiliations of Nathan Mise include Salk Institute for Biological Studies & Hokkaido University.
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Journal ArticleDOI
Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits
Keigo Kohara,Michele Pignatelli,Alexander J. Rivest,Hae Yoon Jung,Takashi Kitamura,Junghyup Suh,Dominic D. Frank,Koichiro Kajikawa,Nathan Mise,Yuichi Obata,Ian R. Wickersham,Susumu Tonegawa +11 more
TL;DR: Using highly cell type–specific transgenic mouse lines, optogenetics and patch-clamp recordings, dentate gyrus cells are found to send functional monosynaptic inputs to CA2 pyramidal cells through abundant longitudinal projections, allowing a deeper understanding of the biology of learning and memory.
Journal ArticleDOI
LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation
Jennifer C. Chow,Constance Ciaudo,Melissa Fazzari,Nathan Mise,Nathan Mise,Nicolas Servant,Nicolas Servant,Nicolas Servant,Jacob L. Glass,Matthew Attreed,Philip Avner,Anton Wutz,Emmanuel Barillot,Emmanuel Barillot,Emmanuel Barillot,John M. Greally,Olivier Voinnet,Edith Heard,Edith Heard,Edith Heard +19 more
TL;DR: It is shown that LINEs participate in creating a silent nuclear compartment into which genes become recruited during X chromosome inactivation, and that such LINE expression requires the specific heterochromatic state induced by Xist.
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Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method
Yoshihide Hayashizaki,Hideo Shibata,Shinji Hirotsune,Hidehiko Sugino,Yasushi Okazaki,Nobuya Sasaki,Kenji Hirose,Hirosumi Imoto,Hisato Okuizumi,Masami Muramatsu,H. Komatsubara,Toshihiko Shiroishi,Kazuo Moriwaki,Motoya Katsuki,Naoya Hatano,Hiroyuki Sasaki,Takayuki Ueda,Nathan Mise,Nobuo Takagi,Christoph Plass,Verne M. Chapman +20 more
TL;DR: A new imprinted gene has been discovered in mice using the technique of restriction landmark genomic scanning (RGLS) with methylation sensitive enzymes and the amino–acid sequence deduced showed significant homology to the U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit.
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Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a.
Shunsuke Kuroki,Shogo Matoba,Mika Akiyoshi,Yasuko Matsumura,Hitoshi Miyachi,Nathan Mise,Kuniya Abe,Atsuo Ogura,Dagmar Wilhelm,Peter Koopman,Masami Nozaki,Yoshiakira Kanai,Yoichi Shinkai,Makoto Tachibana +13 more
TL;DR: A pivotal role of histone demethylation in mammalian sex determination is revealed and is observed in mouse male-to-female sex reversal and Jmjd1a directly and positively controls Sry expression by regulating H3K9me2 marks.
Journal ArticleDOI
Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.
Shin Kobayashi,Ayako Isotani,Nathan Mise,Masamichi Yamamoto,Yoshitaka Fujihara,Kazuhiro Kaseda,Tomoko Nakanishi,Masahito Ikawa,Hiroshi Hamada,Kuniya Abe,Masaru Okabe +10 more
TL;DR: Using enhanced green fluorescent protein-tagged X chromosomes to identify the sex of the embryos, gene expression patterns between male and female mouse blastocysts were compared by DNA microarray and indicated sex differences in early epigenetic gene regulation.