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Biodegradable and electrically conducting polymers for biomedical applications

TLDR
Conducting polymers have been widely used in biomedical applications such as biosensors and tissue engineering but their non-degradability still poses a limitation.
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This article is published in Progress in Polymer Science.The article was published on 2013-09-01. It has received 498 citations till now.

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Conductive polymers: towards a smart biomaterial for tissue engineering.

TL;DR: Focusing mainly on polypyrrole, polyaniline and poly(3,4-ethylenedioxythiophene), this work reviews conductive polymers from the perspective of tissue engineering.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing

TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.

TL;DR: In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.
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Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing

TL;DR: These adhesive hemostatic antioxidant conductive photothermal antibacterial hydrogels based on hyaluronic acid-graft-dopamine and reduced graphene oxide using a H2 O2 /HPR (horseradish peroxidase) system are prepared for wound dressing and are an excellent wound dressing for full-thickness skin repair.
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Injectable antibacterial conductive nanocomposite cryogels with rapid shape recovery for noncompressible hemorrhage and wound healing.

TL;DR: The authors report on the development of injectable, biocompatible carbon nanotube reinforced quaternized chitosan cryogels with shape memory, conductivity and antibacterial properties for hemostatic control for lethal noncompressible hemorrhage hemostasis and wound healing.
References
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Journal ArticleDOI

Electroactive Hydrophilic Polylactide Surface by Covalent Modification with Tetraaniline

TL;DR: In this paper, maleic anhydride and acrylic acid were photografted onto a polylactide (PLA) surface with a grafting from method to increase the surface wettability, and the subsequent coupling of conductive aniline oligomer was used to introduce electroactivity to the PLA surface.
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Universal Two-Step Approach to Degradable and Electroactive Block Copolymers and Networks from Combined Ring-Opening Polymerization and Post-Functionalization via Oxidative Coupling Reactions

TL;DR: In this paper, a universal strategy for the facile synthesis of degradable and electroactive block copolymers and organogels (DEBCGs) based on aniline tetramer and poly(e-caprolactone) was presented.
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Enzyme-Catalyzed Ring-Opening Polymerization of Seven-Membered Ring Lactones Leading to Terminal-Functionalized and Triblock Polyesters

TL;DR: In this paper, terminal functionalized polyesters and triblock polyesters were synthesized by lipase-CA-catalyzed ring-opening polymerization of seven-membered ring lactones, in the presence of an appropriate alcohol that acts as an initiator.
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Versatile functionalization of polyester hydrogels with electroactive aniline oligomers

TL;DR: In this article, the authors proposed a method to lower the aniline oligomer content while maintaining the degradability of polyester hydrogels with functionalizing aliphatic polyester.
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Oligoethylene-glycol-functionalized polyoxythiophenes for cell engineering: syntheses, characterizations, and cell compatibilities.

TL;DR: The results indicate that oligoethylene-glycol-functionalized polyoxythiophenes are promising candidates as conducting biomatierals for biomedical and bioengineering applications.
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