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Biodegradable and electrically conducting polymers for biomedical applications

TLDR
Conducting polymers have been widely used in biomedical applications such as biosensors and tissue engineering but their non-degradability still poses a limitation.
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This article is published in Progress in Polymer Science.The article was published on 2013-09-01. It has received 498 citations till now.

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Interwoven Aligned Conductive Nanofiber Yarn/Hydrogel Composite Scaffolds for Engineered 3D Cardiac Anisotropy

TL;DR: This work presents a 3D hybrid scaffold based on aligned conductive nanofiber yarns network (NFYs-NET, composition: polycaprolactone, silk fibroin, and carbon nanotubes) within a hydrogel shell for mimicking the native cardiac tissue structure and demonstrates their great potential for engineering 3D cardiac anisotropy for cardiac tissue engineering.
Journal ArticleDOI

Tissue engineering of electrically responsive tissues using polyaniline based polymers: a review.

TL;DR: It is concluded that electroactive PANI and its derivatives show great promise in eliciting favorable responses from various cell lines that respond to electrical stimuli, and are therefore effective biomaterials for the engineering of electrically responsive biological tissues and organs.
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pH-responsive injectable hydrogels with mucosal adhesiveness based on chitosan-grafted-dihydrocaffeic acid and oxidized pullulan for localized drug delivery.

TL;DR: A series of multifunctional injectable mucoadhesive and pH-responsive hydrogels based on chitosan-grafted-dihydrocaffeic acid and oxidized pullulan via a Schiff base reaction are developed, suggesting their potential use in mucosa-localized drug delivery systems.
Journal ArticleDOI

Injectable antibacterial conductive hydrogels with dual response to an electric field and pH for localized “smart” drug release

TL;DR: A series of injectable conductive hydrogels based on chitosan-graft-polyaniline (CP) copolymer and oxidized dextran (OD) with "smart" delivery vehicles with electro-responsiveness and pH-responsive properties for triggered and localized release of drugs are designed.
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Nanofiber Yarn/Hydrogel Core-Shell Scaffolds Mimicking Native Skeletal Muscle Tissue for Guiding 3D Myoblast Alignment, Elongation, and Differentiation.

TL;DR: Data suggest that these core-shell scaffolds combine the aligned NFY core that guides the myoblast alignment and differentiation and the hydrogel shell that provides a suitable 3D environment for nutrition exchange and mechanical protection to perform a great practical application for skeletal muscle regeneration.
References
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Journal ArticleDOI

Chitin and chitosan: Properties and applications

TL;DR: Chitin is the second most important natural polymer in the world as mentioned in this paper, and the main sources of chitin are two marine crustaceans, shrimp and crabs, which are used for food, cosmetics, biomedical and pharmaceutical applications.
Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Scaffolds in tissue engineering bone and cartilage.

TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
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Biodegradable polymers as biomaterials

TL;DR: This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.
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