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Biodegradable and electrically conducting polymers for biomedical applications

TLDR
Conducting polymers have been widely used in biomedical applications such as biosensors and tissue engineering but their non-degradability still poses a limitation.
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This article is published in Progress in Polymer Science.The article was published on 2013-09-01. It has received 498 citations till now.

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Conductive polymers: towards a smart biomaterial for tissue engineering.

TL;DR: Focusing mainly on polypyrrole, polyaniline and poly(3,4-ethylenedioxythiophene), this work reviews conductive polymers from the perspective of tissue engineering.
Journal ArticleDOI

Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing

TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Journal ArticleDOI

Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.

TL;DR: In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.
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Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing

TL;DR: These adhesive hemostatic antioxidant conductive photothermal antibacterial hydrogels based on hyaluronic acid-graft-dopamine and reduced graphene oxide using a H2 O2 /HPR (horseradish peroxidase) system are prepared for wound dressing and are an excellent wound dressing for full-thickness skin repair.
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Injectable antibacterial conductive nanocomposite cryogels with rapid shape recovery for noncompressible hemorrhage and wound healing.

TL;DR: The authors report on the development of injectable, biocompatible carbon nanotube reinforced quaternized chitosan cryogels with shape memory, conductivity and antibacterial properties for hemostatic control for lethal noncompressible hemorrhage hemostasis and wound healing.
References
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Journal ArticleDOI

Electrochemically synthesised conducting polymeric materials for applications towards technology in electronics, optoelectronics and energy storage devices

TL;DR: The state of the art of novel electronically conducting polymeric materials is presented in this article, where the special emphasis is laid on the electrochemical synthesis of conducting polymers (CPs) including the choice of the monomers and solvents, supporting electrolytes and electrodes and structural aspects of these novel materials and the nature of the dopants which induce electrical conductivity in conjugated organic polymers.
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Polypyrrole-based conducting polymers and interactions with biological tissues.

TL;DR: This paper reviews studies that have considered such PPy based conducting polymers in direct contact with biological tissues and concludes that due to its versatile functional properties, it could contribute to a new generation of biomaterials.
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Evaluation of biocompatibility of polypyrrole in vitro and in vivo.

TL;DR: PPy has a good biocompatibility with rat peripheral nerve tissue and that PPy might be a candidate material for bridging the peripheral nerve gap according to the results of this study.
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Electrochemically controlled drug delivery based on intrinsically conducting polymers.

TL;DR: It is concluded that ICPs hold great promise in drug delivering implants where the dose can be adjusted through application of external stimulus, thus optimising benefit to side effect ratio while simultaneously ensuring patient adherence.
Journal ArticleDOI

Synthesis of a Novel, Biodegradable Electrically Conducting Polymer for Biomedical Applications

TL;DR: A novel biomaterial that possesses the unique properties of being both electrically conducting and biodegradable; and thus capable of electronic interfacing with tissue is reported, which is conductive, degradable, and biocompatible.
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