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Journal ArticleDOI

Biological and Chemical Databases for Research into the Composition of Animal Source Foods

TLDR
This review presents examples of freely available databases (without obligatory registration) listing major groups of bioactive components, including nucleic acids, proteins, peptides, carbohydrates, lipids, and low-molecular-weight compounds.
Abstract
Bioinformatics and cheminformatics tools such as databases play an increasingly important role in modern science. They are commonly used in biological and medical sciences and they have many applications in food science. Databases listing biologically active compounds contribute to the design of functional foods and nutraceuticals. Databases of toxic or allergenic compounds are useful for food safety evaluations. This review presents examples of freely available databases (without obligatory registration) listing major groups of bioactive components. The main categories of compounds annotated in online databases include nucleic acids, proteins, peptides, carbohydrates, lipids, and low-molecular-weight compounds. Other categories of database entries are also discussed, including enzymes, allergens and their epitopes, flavor-enhancing compounds, as well as toxic substances. The last section of the review focuses on metabases, which are Web sites that create access to multiple databases.

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Journal ArticleDOI

Chemometrics and cheminformatics in the analysis of biologically active peptides from food sources

TL;DR: An overview of the most popular chemometric/cheminformatic methods used to analyze the food-derived bioactive peptides, including artificial neural networks, principal component analysis, partial least squares and quantitative structure–activity relationship approaches are presented.
Journal ArticleDOI

Angiotensin I-converting enzyme (ACE) inhibitory activity and ACE inhibitory peptides of salmon (Salmo salar) protein hydrolysates obtained by human and porcine gastrointestinal enzymes.

TL;DR: In this paper, a two-step ex vivo and in vitro model digestion was performed to simulate the human digestion process, and it was shown that salmon proteins were degraded more efficiently by porcine enzymes than by human gastrointestinal juices and sarcoplasmic proteins were digested/hydrolyzed more easily than myofibrillar proteins.
Journal ArticleDOI

Understanding the nature of bitter-taste di- and tripeptides derived from food proteins based on chemometric analysis

TL;DR: The bitterness of a peptide resulting from the presence of specific residues in its sequence, which represent different physicochemical properties may contribute to extending the knowledge about their taste-forming role in food systems.
Journal ArticleDOI

Properties of bovine colostrum and the possibilities of use

TL;DR: The interest in questioned substance is rising due to vast scientific and clinical research underlining the significance of colostrum in feeding of human beings and scientists predict that products based on colostrums may play a significant role on the functional products market in the future.
References
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Journal ArticleDOI

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

TL;DR: A new criterion for triggering the extension of word hits, combined with a new heuristic for generating gapped alignments, yields a gapped BLAST program that runs at approximately three times the speed of the original.
Journal ArticleDOI

Identification of common molecular subsequences.

TL;DR: This letter extends the heuristic homology algorithm of Needleman & Wunsch (1970) to find a pair of segments, one from each of two long sequences, such that there is no other Pair of segments with greater similarity (homology).
Journal ArticleDOI

Database resources of the National Center for Biotechnology Information

TL;DR: In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI’s website.
Book ChapterDOI

Protein identification and analysis tools in the ExPASy server

TL;DR: Details are given about protein identification and analysis software that is available through the ExPASy World Wide Web server and the extensive annotation available in the Swiss-Prot database is used.
Journal ArticleDOI

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

TL;DR: The SWISS-MODEL workspace is a web-based integrated service dedicated to protein structure homology modelling that assists and guides the user in building protein homology models at different levels of complexity.
Related Papers (5)
Trending Questions (1)
What are the most commonly used databases for storing and accessing biopeptides of animal origin?

The BIOPEP database is commonly used for storing and accessing biopeptides of animal origin, particularly by food scientists according to the research paper.