scispace - formally typeset
Journal ArticleDOI

Biotechnology report. Solid state fermentations.

Hesseltine Cw
- 01 Jul 1972 - 
- Vol. 14, Iss: 4, pp 517-532
TLDR
A unique method is described by which large yields of secondary metabolites arc produced on solid substrates using Aspergillus and Penicillium species, which prevents sporulation of the fungus and makes recovery of the product easier than in conventional liquid media.
Abstract
A unique method is described by which large yields of secondary metabolites arc produced on solid substrates. The process involves the use of moist substrates which are continuously agitated in appropriate fermentation equipment. The amount of agitation, aeration, and moisture can be varied. Extremely high yields of secondary metabolites such as ochratoxin and aflatoxin were obtained using Aspergillus and Penicillium species. The process prevents sporulation of the fungus and because of the nature of the solid substrate makes recovery of the product easier than in conventional liquid media. The substrates include rice, corn, wheat, and other cereals.

read more

Citations
More filters
Journal ArticleDOI

Design of solid state fermentor for production of fungal metabolites on large scale.

TL;DR: A large scale solid state fermentor of 150 tray capacity with appropriate control system was designed in this article, which gave better productivity even at higher scale of operation as compared to lab and large scale units of similar type and largely overcomes some operational problems.
Journal ArticleDOI

Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.

TL;DR: Production of luteoskyrin, a hepatotoxin synthesized by Penicillium islandicum Sopp.
Journal ArticleDOI

Influence of ochratoxin B on the ochratoxin A inhibition of phenylalanyl-tRNA formation in vitro and protein synthesis in hepatoma tissue culture cells

TL;DR: The results are not in favor of an antagonistic effect of OTB with respect to OTA action, at least on the level of cellular protein synthesis.
Journal ArticleDOI

Enrichment of wheat bran by rhodotorula gracilis through solid-state fermentation

TL;DR: The potential oil-producing yeast Rhodotorula gracilis was found to produce higher yields of biomass and lipids in a nitrogen-limited and economically cheaper medium and did not produceα-amylase, amyloglucosidase and cellulolytic enzymes for the breakdown of wheat bran.
References
More filters
Journal ArticleDOI

Production of aflatoxin on rice.

TL;DR: A method has been developed for the production of aflatoxin by growing Aspergillus flavus strain NRRL 2999 on the solid substrate rice using chloroform-hexane mixtures.
Journal ArticleDOI

A millennium of fungi, food, and fermentation.

TL;DR: Procedures for the pure culture preparation of some fermented but nonalcoholic foods are outlined, including tempeh, ragi, sufu, shoyu, ang-kak, tea fungus, and miso.
Journal ArticleDOI

Production of aflatoxin on wheat and oats: measurement with a recording densitometer.

TL;DR: A densitometric method for reading thin-layer chromatographic plates is described; this is more objective and more accurate than the visual methods previously used for the determination of all four aflatoxins.
Journal ArticleDOI

Microbiological Production of Carotenoids. I. Zygospores and Carotene Produced by Intraspecific and Interspecific Crosses of Choanephoraceae in Liquid Media

TL;DR: It is reported that plus and minus strains of Choanephora cucurbitarum were capable of forming zygospores when grown together in liquid medium in shaken flasks, and yields of 960 t/g/g of 8-carotene in dry mycelium were found.