Journal ArticleDOI
Bone loss during menopausal transition among southern Chinese women
Elaine Cheung,Shirley Wan-yin Tsang,Cora Bow,Cissy Soong,Shirley S. C. Yeung,Connie Hong Nin Loong,Ching-Lung Cheung,Ching-Lung Cheung,Anita Kan,Sue Lo,Sidney Tam,Grace W.K. Tang,Annie Kung +12 more
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TLDR
Strategies to retard bone loss should be stressed to middle aged women, especially those with lean body built or with early menopause, to prevent osteoporosis later on in life.About:
This article is published in Maturitas.The article was published on 2011-05-01. It has received 47 citations till now. The article focuses on the topics: Bone mineral & Osteoporosis.read more
Citations
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Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis
Ling-Ling Zhu,Harry C. Blair,Harry C. Blair,Jay Cao,Tony Yuen,Rauf Latif,Lida Guo,Irina L. Tourkova,Jianhua Li,Terry F. Davies,Li Sun,Zhuan Bian,Clifford J. Rosen,Alberta Zallone,Maria I. New,Mone Zaidi +15 more
TL;DR: It is shown that the FSH antibody binds FSH specifically and blocks its action on osteoclast formation in vitro and prompts the future development of an FSH-blocking agent as a means of uncoupling bone formation and bone resorption to a therapeutic advantage in humans.
Journal ArticleDOI
Pituitary Diseases and Bone
TL;DR: Treatment of pituitary hormone excess and deficiency generally improves skeletal health, although some patients remain at high risk of fractures, and treatment with bone-active drugs may become mandatory.
Journal ArticleDOI
Age and sex related differences in subcortical brain iron concentrations among healthy adults.
Ninni Persson,Jianlin Wu,Qing Zhang,Ting Liu,Jing Shen,Ruyi Bao,Mingfei Ni,Tian Liu,Yi Wang,Pascal Spincemaille +9 more
TL;DR: This is the first in-vivo report to show lower total subcortical brain iron levels selectively in women from midlife, compared to men and younger women, and encourages further assessment of sex differences in brain iron.
Journal ArticleDOI
Follicle-Stimulating Hormone Increases the Risk of Postmenopausal Osteoporosis by Stimulating Osteoclast Differentiation
TL;DR: The circulating concentration of FSH may play an important role in the acceleration of bone loss in postmenopausal women.
Journal ArticleDOI
Association between vitamin D insufficiency and elevated serum uric acid among middle-aged and elderly Chinese Han women.
TL;DR: Vitamin D insufficiency was significantly associated with elevated uric acid among postmenopausal Chinese Han women and a clinical trial should be conducted to confirm the association of vitamin D Insufficiency with hyperuricemia.
References
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Hip fractures in the elderly: A world-wide projection
TL;DR: In this article, the authors applied available incidence rates for hip fracture from various parts of the world to projected populations in 1990, 2025 and 2050 in order to estimate the numbers of hip fractures which might occur in each of the major continental regions.
Hip fractures in the elderly: a worldwide projection
C Cooper,G. Campion,L. J. Melton +2 more
TL;DR: The results suggest that osteoporosis will truly become a global problem over the next half century, and that preventive strategies will be required in parts of the world where they are not currently felt to be necessary.
Journal ArticleDOI
Bone Quality — The Material and Structural Basis of Bone Strength and Fragility
Ego Seeman,Pierre D. Delmas +1 more
TL;DR: In this article, a review discusses advances in knowledge regarding the composition and structure of bone, the modeling and remodeling of bone and the formation of bone during growth and its reconstruction in adults.
Journal ArticleDOI
Bone Mineral Density Changes during the Menopause Transition in a Multiethnic Cohort of Women
Joel S. Finkelstein,Sarah Brockwell,Vinay Mehta,Gail A. Greendale,MaryFran Sowers,Bruce Ettinger,Joan C. Lo,Janet M. Johnston,Jane A. Cauley,Michelle E. Danielson,Robert M. Neer +10 more
TL;DR: A longitudinal cohort study of 1902 African-American, Caucasian, Chinese, or Japanese women participating in The Study of Women’s Health Across the Nation assessed rates of bone loss at each stage of the transition and examined major factors that modify those rates.
Journal ArticleDOI
Sex steroids and bone mass. A study of changes about the time of menopause.
TL;DR: Multivariate regressions showed estrogen concentrations to be strong independent predictors of the slope of bone mass over time, and when BGP concentrations were added to the models, the significance of estrogen was reduced, suggesting that a portion of the estrogen effect was mediated through effects on rates of bone remodelling.
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Li Sun,Yuanzhen Peng,Allison C. Sharrow,Allison C. Sharrow,Jameel Iqbal,Zhiyuan Zhang,Dionysios J. Papachristou,Dionysios J. Papachristou,Samir Zaidi,Ling-Ling Zhu,Beatrice B. Yaroslavskiy,Beatrice B. Yaroslavskiy,Hang Zhou,Alberta Zallone,M. Ram Sairam,T. Rajendra Kumar,Wei Bo,Jonathan Braun,Luis Cardoso-Landa,Mitchell B. Schaffler,Baljit S. Moonga,Harry C. Blair,Harry C. Blair,Mone Zaidi +23 more